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Categories: Biology: Developmental, Biology: Evolutionary

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Researchers have spotted how specific proteins within the chromosomes of roundworms enable their offspring to produce specialized cells generations later, a startling finding that upends classical thinking that hereditary information for cell differentiation is mostly ingrained within DNA and other genetic factors.

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A new look at decades of data from museum collections and surveys of leaf-litter ants in Florida reveals a steady decline in native ants and simultaneous increase in nonnative ants -- even in protected natural areas of the state, researchers report.

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A team of researchers compared the genomes of woolly mammoths with modern day elephants to find out what made woolly mammoths unique, both as individuals and as a species. The investigators report that many of the woolly mammoth's trademark features -- including their woolly coats and large fat deposits -- were already genetically encoded in the earliest woolly mammoths, but these and other traits became more defined over the species' 700,000+ year existence. They also identified a gene with several mutations that may have been responsible for the woolly mammoth's miniscule ears.

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A team has developed an ingenious device, using layers of hydrogels in a cube-like structure, that allows researchers to construct complex 3D organoids without using elaborate techniques. The group also recently demonstrated the ability to use the device to build organoids that faithfully reproduce the asymmetric genetic expression that characterizes the actual development of organisms.

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New research investigates how cells divide, particularly in the fibrous environment of living tissue. Cells are typically studied in a flat environment, and the difference between flat and fibrous landscapes opens new windows into the behavior of cells and the diseases that impact them.

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A team of researchers reconstructed long-extinct proteins of a UV protection system of cyanobacteria. The surprising result: the proteins were already compatible with each other when they first met. This discovery expands the knowledge horizon on the rules of evolution.

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Human embryo development and early organ formation remain largely unexplored due to ethical issues surrounding the use of embryos for research as well as limited availability of materials to study. Investigators now report on the creation of embryo-like structures from monkey embryonic stem cells. The investigators also transferred these embryo-like structures into the uteruses of female monkeys and determined that the structures were able to implant and elicit a hormonal response similar to pregnancy.

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Biologists have explored the genetic mechanisms underlying the transition from freezing Antarctic waters to more temperature waters by Antarctic Notothenioid fish.

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What defines the habitat -- the ecological niche -- of a microorganism? It is a combination of environmental factors such as temperature, moisture, and nutrient content. But the exact contribution of each of these factors is difficult to predict. A research team has redefined microbial niches by determining which microorganisms live together.

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A team has induced stem cells to emulate the development of the human heart. The result is a sort of 'mini-heart' known as an organoid. It will permit the study of the earliest development phase of our heart and facilitate research on diseases.

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Human culture and language may be the result of 'self-domestication': an evolutionary process that leads to less aggressive and more prosocial individuals. A research team argues that elephants -- like humans and bonobos -- may also be self-domesticated. Elephants show many traits associated with self-domestication, such as prosocial behavior, playfulness and complex communication skills. This makes elephants an interesting new animal model for the evolution of prosociality.

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Fresh insights into how our bodies interact with the microbes living in our guts suggest that a two-drug combination may offer a new way to treat inflammatory bowel diseases such as Crohn's disease and ulcerative colitis.

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While pollinator populations of many species have plummeted worldwide, one bee species is blowing up the map with its rapid population expansion. The key to this insect's success? Its passion for pumpkins, zucchinis, and other squashes, and the massive increase in cultivation of these crops across North America over the last 1,000 years. A new study found that the squash bee (Eucera pruinosa) has evolved in response to intensifying agriculture -- namely squashes in the genus Curcurbita. The research has demonstrated the role of agriculture as an evolutionary force acting on a wild insect pollinator and may have implications for food security.

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Today, ants are pretty much everywhere. To learn more about how these insects conquered the world, scientists used a combination of fossils, DNA, and data on the habitat preferences of modern species to piece together how ants and plants have been evolving together over the past 60 million years. They found that when flowering plants spread out from forests, the ants followed, kicking off the evolution of the thousands of ant species alive today.

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Researchers have developed a technology for delivering a microrobot to a target point of a hippocampus in an in-vitro environment, connecting neural networks, and measuring neural signals. The findings are expected to contribute to neural network research and the verification and analysis of cell therapy products.

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Aging cells express a protein that is produced by human cytomegalovirus and is targeted by certain immune cells in the body. Harnessing the immune response to this protein could have multiple health benefits during aging.

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New research has discovered a cold 'coping' mechanism that is under the control of the plant biological clock and could offer solutions to breeding more resilience into crops less suited to cold climates.

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Acetylcholine regulates blood flow, but the source of blood acetylcholine has been unclear. Now, researchers have discovered that certain T cells in human blood can produce acetylcholine, which may help regulate blood pressure and inflammation. The study also demonstrates a possible association between these immune cells in seriously ill patients and the risk of death.

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The Indo-West Pacific is the largest marine ecosystem on Earth, but scientists who study its diversity have to contend with a problem so well-known it was remarked upon by Charles Darwin: related species in the IWP have similar appearances, making it difficult to assess just how many there are. A new study reveals that nearly identical crab species have one consistently distinguishing feature, which only evolves when their ranges overlap.

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Researchers discover that actin acts in the cell nucleus and is partly responsible for the expression of male sexual characteristics.