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Categories: Biology: Evolutionary, Chemistry: Biochemistry
Published Researchers teaching artificial intelligence about frustration in protein folding
(via sciencedaily.com) Original source Scientists have found a new way to predict how proteins change their shape when they function, which is important for understanding how they work in living systems. While recent artificial intelligence (AI) technology has made it possible to predict what proteins look like in their resting state, figuring out how they move is still challenging because there is not enough direct data from experiments on protein motions to train the neural networks.
Published 'Masters of shape-shifting': How darkling beetles conquered the world
(via sciencedaily.com) Original source Large-scale genomic analysis of darkling beetles, a hyper-diverse insect group of more than 30,000 species worldwide, rolls back the curtain on a 150-million-year evolutionary tale of one of Earth's most ecologically important yet inconspicuous creatures, according to new research.
Published Explanation found for X-ray radiation from black holes
(via sciencedaily.com) Original source Researchers have succeeded in something that has been pursued since the 1970s: explaining the X-ray radiation from the black hole surroundings. The radiation originates from the combined effect of the chaotic movements of magnetic fields and turbulent plasma gas.
Published 'Molecular compass' points way to reduction of animal testing
(via sciencedaily.com) Original source Machine learning models have become increasingly popular for risk assessment of chemical compounds. However, they are often considered 'black boxes' due to their lack of transparency. To increase confidence in these models, researchers proposed carefully identifying the areas of chemical space where these models are weak. They developed an innovative software tool for this purpose, and the results of this research approach have just been published.
Published A new reaction to enhance aromatic ketone use in chemical synthesis
(via sciencedaily.com) Original source Researchers develop a one pot process to transform aromatic ketones to esters, offering advancements in pharmaceutical synthesis and materials science.
Published Investigating the interplay of folding and aggregation in supramolecular polymer systems
(via sciencedaily.com) Original source Scientists have developed photoresponsive supramolecular polymers that can undergo both intrachain folding and interchain aggregation.
Published Adaptive 3D printing system to pick and place bugs and other organisms
(via sciencedaily.com) Original source A new adaptive 3D printing system can identify the positions of randomly distributed organisms and safely move them to specific locations for assembly.
Published Scientists discover new code governing gene activity
(via sciencedaily.com) Original source A newly discovered code within DNA -- coined 'spatial grammar' -- holds a key to understanding how gene activity is encoded in the human genome. This breakthrough finding revealed a long-postulated hidden spatial grammar embedded in DNA. The research could reshape scientists' understanding of gene regulation and how genetic variations may influence gene expression in development or disease.
Published Scientists harness quantum microprocessor chips for revolutionary molecular spectroscopy simulation
(via sciencedaily.com) Original source Engineering researchers have successfully developed a quantum microprocessor chip for molecular spectroscopy simulation of actual large-structured and complex molecules.
Published Key biofuel-producing microalga believed to be a single species is actually three
(via sciencedaily.com) Original source When a global pandemic forced previous a graduate student out of the lab and onto the computer, he found a world of difference hidden in the long-studied species of Botryoccocus braunii -- and discovered that it isn't one species at all, but three.
Published Wearable, stretchable sensor for quick, continuous, and non-invasive detection of solid-state skin biomarkers
(via sciencedaily.com) Original source Detecting diseases early requires the rapid, continuous and convenient monitoring of vital biomarkers. Researchers have now developed a novel sensor that enables the continuous, and real-time detection of solid-state epidermal biomarkers, a new category of health indicators. The team's wearable, stretchable, hydrogel-based sensor overcomes the limitations of current methods that rely on biofluid samples, such as blood, urine and sweat. This makes it a promising alternative for wearable, continuous, and real-time health monitoring, facilitating the early detection of conditions such as cardiovascular diseases and stroke.
Published Morphable materials: Researchers coax nanoparticles to reconfigure themselves
(via sciencedaily.com) Original source A view into how nanoscale building blocks can rearrange into different organized structures on command is now possible with an approach that combines an electron microscope, a small sample holder with microscopic channels, and computer simulations, according to a new study.
Published Taming Parkinson's disease with intelligent brain pacemakers
(via sciencedaily.com) Original source Two new studies are pointing the way toward round-the-clock personalized care for people with Parkinson's disease through an implanted device that can treat movement problems during the day and insomnia at night.
Published Researchers develop new chemical method to enhance drug discovery
(via sciencedaily.com) Original source Researchers developed a novel reagent that enhances the precision of drug synthesis. This innovative method introduces a new sulfur fluoride exchange (SuFEx) reagent that allows for highly controlled production of crucial sulfur-based molecules, including sulfinamides, sulfonimidamides and sulfoximines.
Published Blind cavefish have extraordinary taste buds
(via sciencedaily.com) Original source A biologist studies blind cavefish, a species of fish that dwell in cave ponds in Mexico. He looked at the timeline for when the cavefish develop additional taste buds on the head and chin, finding the taste bud expansion starts at five months and continues into adulthood.
Published Research provides a roadmap for improving electrochemical performance
(via sciencedaily.com) Original source A study expands understanding on how electrons move through the conductive parts of complex fluids found in electrochemical devices such as batteries. This work can help overcome existing knowledge gaps for engineers seeking to improve the performance of these devices.
Published New technique prints metal oxide thin film circuits at room temperature
(via sciencedaily.com) Original source Researchers have demonstrated a technique for printing thin metal oxide films at room temperature, and have used the technique to create transparent, flexible circuits that are both robust and able to function at high temperatures.
Published New microscope offers faster, high-resolution brain imaging
(via sciencedaily.com) Original source Researchers have developed a new two-photon fluorescence microscope that captures high-speed images of neural activity at cellular resolution. By imaging much faster and with less harm to brain tissue than traditional two-photon microscopy, the new approach could provide a clearer view of how neurons communicate in real time, leading to new insights into brain function and neurological diseases.
Published Quantum pumping in molecular junctions
(via sciencedaily.com) Original source Researchers have developed a new theoretical modelling technique that could potentially be used in the development of switches or amplifiers in molecular electronics.
Published Scientists map DNA of Lyme disease bacteria
(via sciencedaily.com) Original source Researchers have produced a genetic analysis of Lyme disease bacteria that may pave the way for improved diagnosis, treatment, and prevention of the tick-borne ailment.