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Categories: Biology: Evolutionary, Chemistry: Biochemistry

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Researchers found a way to screen cancer-linked gene mutations much more easily and quickly than existing approaches, using a variant of CRISPR genome-editing known as prime editing.

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Giraffes, with their bizarre body plan, have always held a special place in the minds of evolutionary biologists and non-experts alike. In a new study whole-genome sequencing data was used to investigate the evolutionary processes occurring within giraffes. In particular, the authors were interested in establishing whether different populations of giraffes really have been isolated from each other for extended periods of time, which is normally a requirement before new species can arise.

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A newly developed 'GPS nanoparticle' injected intravenously can home in on cancer cells to deliver a genetic punch to the protein implicated in tumor growth and spread, according to researchers. They tested their approach in human cell lines and in mice to effectively knock down a cancer-causing gene, reporting that the technique may potentially offer a more precise and effective treatment for notoriously hard-to-treat basal-like breast cancers.

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In the quest to develop quantum computers and networks, there are many components that are fundamentally different than those used today. Like a modern computer, each of these components has different constraints. However, it is currently unclear what materials can be used to construct those components for the transmission and storage of quantum information.

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A team develops an ultrasensitive broadband transparent ultrasound transducer.

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Artificial intelligence (AI) is known for its high energy consumption, especially in data-intensive tasks like health monitoring. To address this, researchers have developed a flexible paper-based sensor composed of nanocellulose and zinc oxide (ZnO) nanoparticles that operates like the human eyes and brain. The sensor is energy-efficient, responds to optical input in real-time, and is both flexible and easy to dispose of, making it ideal for health monitoring applications.

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Scientists reveal new lineages of giant sea anemones in Japan and their surprising associations with anemonefish.

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Monitoring daily activity patterns using a wrist-worn device may detect early warning signs of Alzheimer's disease, according to a new study.

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Researchers have painstakingly taken computed topography (CT) scans of more than 13,000 individual specimens to create 3D images of more than half of all the world's animal groups, including mammals, fishes, amphibians and reptiles.

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Researchers have used tip-scan high-speed atomic force microscopy combined with an optical microscope to observe light-induced deformation of azo-polymer films. The process could be followed in real time, and the film patterns were found to change with the polarization of the light source. The observations will contribute to the use of azo-polymers in applications such as optical data storage, and the approach is expected to be useful across materials science and physical chemistry.

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Researchers have discovered a mechanism steering the evolution of multicellular life. They identified how altered protein folding drives multicellular evolution.

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Biologists present groundbreaking research shedding new light on the evolution of social bonds and cooperation among group-living animals.

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The combination of OLEDs and acoustic antennas creates a light source that could be used for minimally invasive treatment methods.

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For the first time, scientists have developed artificial nucleotides, the building blocks of DNA, with several additional properties in the laboratory.

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When you teach a child how to solve puzzles, you can either let them figure it out through trial and error, or you can guide them with some basic rules and tips. Similarly, incorporating rules and tips into AI training -- such as the laws of physics --could make them more efficient and more reflective of the real world. However, helping the AI assess the value of different rules can be a tricky task.

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A new field promises to usher in a new era of using machine learning and computer vision to tackle small and large-scale questions about the biology of organisms around the globe.

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All modern Plasmodium falciparum, the deadliest malaria parasite in humans, are descendants of one initial infection and so are very closely related, with relatively limited genetic differences. A long-standing mystery in the field has revolved around a very few locations in the P. falciparum genome where there are 'spikes' of mutations -- far more than anywhere else. Researchers have identified two genes in which these unusual mutation spikes result from DNA being copied and pasted from one gene to another.

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Early experiences in an animal's life can have a significant impact on its capacity to thrive, even years or decades later, and DNA methylation may help record their effects. In a study of 256 wild baboons, researchers found that resource limitation during early life was associated with many differences in DNA methylation, a small chemical mark on the DNA sequence that can affect gene activity.

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New research has found that rubisco -- the enzyme that fuels all life on Earth -- is not stuck in an evolutionary rut after all. The largest analysis of rubisco ever has found that it is improving all the time -- just very, very slowly. These insights could potentially open up new routes to strengthen food security.

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Researchers have discovered that nanoscale devices harnessing the hydroelectric effect can harvest electricity from the evaporation of fluids with higher ion concentrations than purified water, revealing a vast untapped energy potential.