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Categories: Biology: Molecular, Chemistry: Organic Chemistry
Published First heat map for individual red blood cells



Entropy is often associated with disorder and chaos, but in biology it is related to energy efficiency and is closely linked to metabolism, the set of chemical reactions that sustain life. An international research team has now developed a novel methodology for the measurement of entropy production at the scale of a nanometer, meaning one-billionth of a meter. The new approach enabled the scientists to measure the heat flow, known as the entropy production rate, of single red blood cells.
Published Universal tool for tracking cell-to-cell interactions



An updated method for directly observing physical interactions between cells, could allow scientists to one day map every possible cell interaction.
Published Synthetic gene helps explain the mysteries of transcription across species



'Random DNA' is naturally active in the one-celled fungi yeast, while such DNA is turned off as its natural state in mammalian cells, despite their having a common ancestor a billion years ago and the same basic molecular machinery, a new study finds.
Published Decoding the language of epigenetic modifications



Epigenetic changes play important roles in cancer, metabolic and aging-related diseases, but also during loss of resilience as they cause the genetic material to be incorrectly interpreted in affected cells. A major study now provides important new insights into how complex epigenetic modification signatures regulate the genome. This study will pave the way for new treatments of diseases caused by faulty epigenetic machineries.
Published Deconstructing the structural elements of a lesser-known microbe



Researchers shed light on archaea, intriguing microbes found in extreme environments but also in the human gut microbiome.
Published New type of nanoparticle makes vaccines more powerful



A type of nanoparticle called a metal organic framework (MOF) could be used to deliver vaccines and act as an adjuvant. Researchers find these particles provoke a strong immune response by activating the innate immune system through cell proteins called toll-like receptors.
Published Key advance toward removing common herbicide from groundwater



Chemists are closing in on a new tool for tackling the global problem of weedkiller-tainted groundwater.
Published Aluminum nanoparticles make tunable green catalysts



A nanotechnology pioneer has uncovered a transformative approach to harnessing the catalytic power of aluminum nanoparticles by annealing them in various gas atmospheres at high temperatures.
Published Using light to precisely control single-molecule devices



Researchers flip the switch at the nanoscale by applying light to induce bonding for single-molecule device switching.
Published Researchers closing in on genetic treatments for hereditary lung disease, vision loss



Researchers who work with tiny drug carriers known as lipid nanoparticles have developed a new type of material capable of reaching the lungs and the eyes, an important step toward genetic therapy for hereditary conditions like cystic fibrosis and inherited vision loss.
Published 'Like a lab in your pocket' -- new test strips raise game in gene-based diagnostics



Biosensing technology developed by engineers has made it possible to create gene test strips that rival conventional lab-based tests in quality.
Published Microalgae with unusual cell biology



A globally distributed single-celled organism that occurs in harmful algal blooms has been found to exhibit an unusual organisation of photosynthesis. Researchers have taken a closer look at the unusual cell biology of the species Prorocentrum cordatum from the group of dinoflagellates. The results of their study could help to better understand the role of the species in the environment and the increased occurrence of algal blooms at higher water temperatures.
Published Modeling the origins of life: New evidence for an 'RNA World'



Scientists provide fresh insights on the origins of life, presenting compelling evidence supporting the 'RNA World' hypothesis. The study unveils an RNA enzyme that can make accurate copies of other functional RNA strands, while also allowing new variants of the molecule to emerge over time. These remarkable capabilities suggest the earliest forms of evolution may have occurred on a molecular scale in RNA, and also bring scientists one step closer to re-creating autonomous RNA-based life in the laboratory.
Published Photosynthetic secrets come to light



Secrets of photosynthesis have been discovered at atomic level, shedding important new light on this plant super-power that greened the earth more than a billion years ago.
Published Convergent evolution of algal CO2-fixing organelles



Researchers identified the proteins of a CO2-fixing organelle, namely, 'pyrenoid,' in the marine algal group Chlorarachniophyta and revealed various pyrenoid-associated proteins among algal groups, suggesting the independent evolution of pyrenoids in different algal groups.
Published AI-enabled atomic robotic probe to advance quantum material manufacturing



Scientists have pioneered a new methodology of fabricating carbon-based quantum materials at the atomic scale by integrating scanning probe microscopy techniques and deep neural networks. This breakthrough highlights the potential of implementing artificial intelligence at the sub-angstrom scale for enhanced control over atomic manufacturing, benefiting both fundamental research and future applications.
Published Light into the darkness of photosynthesis



Researchers succeed at generating 3D visualizations of chloroplasts' copying machines.
Published How virus causes cancer: Potential treatment



Researchers have discovered a key mechanism used by Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV8), to induce cancer. The research points to effective new treatment options for KSHV-associated cancers, including Kaposi's sarcoma, primary effusion lymphoma, and HHV8-associated multicentric Castleman disease.
Published New role for bacterial enzyme in gut metabolism revealed



Bile acids long have been known to play a role in human metabolism. Synthesized from cholesterol in the liver, bile acids are involved in digestive processes, particularly in absorbing fat. They also are modified extensively by bacteria, which greatly expand the types of bile acids found in the host. For most of a century, scientists believed that was the end of the bile-acid story. Recent technological advances, however, have led to a greater understanding of the origins of bile acids as well as their chemical relationships to the organisms in the gut microbiome and their host.
Published Scientists identify new 'regulatory' function of learning and memory gene common to all mammalian brain cells



Neuroscientists say they have found a new function for the SYNGAP1 gene, a DNA sequence that controls memory and learning in mammals, including mice and humans.