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Categories: Biology: Molecular, Chemistry: Organic Chemistry
Published Groundbreaking discovery enables cost-effective and eco-friendly green hydrogen production
(via sciencedaily.com) Original source A research team has developed a novel catalyst for the high-efficiency and stable production of high-purity green hydrogen.
Published Single-celled kamikazes spearhead bacterial infection
(via sciencedaily.com) Original source You suddenly feel sick -- pathogenic bacteria have managed to colonize and spread in your body! The weapons they use for their invasion are harmful toxins that target the host's defense mechanisms and vital cell functions. Before these deadly toxins can attack host cells, bacteria must first export them from their production site -- the cytoplasm -- using dedicated secretion systems.
Published Physical processes can have hidden neural network-like abilities
(via sciencedaily.com) Original source A new study shows that the physics principle of 'nucleation' can perform complex calculations that rival a simple neural network. The work may suggest avenues for new ways to think about computation using the principles of physics.
Published Machine learning method speeds up discovery of green energy materials
(via sciencedaily.com) Original source Researchers have developed a framework that uses machine learning to accelerate the search for new proton-conducting materials, that could potentially improve the efficiency of hydrogen fuel cells.
Published Chemical synthesis: New strategy for skeletal editing on pyridines
(via sciencedaily.com) Original source A team has introduced a strategy for converting carbon-nitrogen atom pairs in a frequently used ring-shaped compound into carbon-carbon atom pairs. The method has potential in the quest for active ingredients for new drugs, for example.
Published DNA construction led to unexpected discovery of important cell function
(via sciencedaily.com) Original source Researchers have used DNA origami, the art of folding DNA into desired structures, to show how an important cell receptor can be activated in a previously unknown way. The result opens new avenues for understanding how the Notch signalling pathway works and how it is involved in several serious diseases.
Published Lighting the path: Exploring exciton binding energies in organic semiconductors
(via sciencedaily.com) Original source Organic semiconductors are materials that find applications in various electronic devices. Exciton binding energy is an important attribute that influences the behavior of these materials. Now, researchers have employed advanced spectroscopic techniques to accurately determine these energies for various organic semiconductor materials, with a high precision of 0.1 electron volts. Their study reveals unexpected correlations that are poised to shape the future of organic optoelectronics, influence design principles, and find potential applications in bio-related materials.
Published New technique visualizes mechanical structure of the cell nucleus
(via sciencedaily.com) Original source The cell nucleus is considered to be the control center of vital cellular processes, but its material properties continue to puzzle scientists. An international research team has now developed a new technique that provides a previously unattainable view of the mechanical properties inside this control center. For the first time, it has been possible to visualize over time its peculiar dynamic structural features in living cells, which appear to be crucial for cell function.
Published Next-generation batteries could go organic, cobalt-free for long-lasting power
(via sciencedaily.com) Original source In the switch to 'greener' energy sources, the demand for rechargeable lithium-ion batteries is surging. However, their cathodes typically contain cobalt -- a metal whose extraction has high environmental and societal costs. Now, researchers in report evaluating an earth-abundant, carbon-based cathode material that could replace cobalt and other scarce and toxic metals without sacrificing lithium-ion battery performance.
Published Cobalt-free batteries could power cars of the future
(via sciencedaily.com) Original source A new battery material could offer a more sustainable way to power electric cars. The lithium-ion battery includes a cathode based on organic materials, instead of cobalt or nickel.
Published Nearly dead plants brought back to life: Keys to aging hidden in the leaves
(via sciencedaily.com) Original source Scientists have known about a particular organelle in plant cells for over a century. However, scientists have only now discovered that organelle's key role in aging.
Published Study throws our understanding of gene regulation for a loop
(via sciencedaily.com) Original source To function properly, the genetic material is highly organized into loop structures that often bring together widely separated sections of the genome critical to the regulation of gene activity. Scientists now address how these loops can help repress or silence gene activity, with potentially far-reaching effects on human health.
Published Machine learning reveals sources of heterogeneity among cells in our bodies
(via sciencedaily.com) Original source A team of scientists discovered the secrets of cell variability in our bodies. The findings of this research are expected to have far-reaching effects, such as improvement in the efficacy of chemotherapy treatments, or set a new paradigm in the study of antibiotic-resistant bacteria.
Published Glowing COVID-19 diagnostic test prototype produces results in one minute
(via sciencedaily.com) Original source Cold, flu and COVID-19 season brings that now-familiar ritual: swab, wait, look at the result. But what if, instead of taking 15 minutes or more, a test could quickly determine whether you have COVID-19 with a glowing chemical? In a new study, researchers describe a potential COVID-19 test inspired by bioluminescence. Using a molecule found in crustaceans, they have developed a rapid approach that detects SARS-CoV-2 protein comparably to one used in vaccine research.
Published Study reveals a reaction at the heart of many renewable energy technologies
(via sciencedaily.com) Original source Chemists have mapped how proton-coupled electron transfers happen at the surface of an electrode. Their results could help researchers design more efficient fuel cells, batteries, or other energy technologies.
Published Unraveling the role of supersulfides in regulating mitochondrial function and longevity
(via sciencedaily.com) Original source Supersulfides, many of which are produced by cysteinyl-tRNA synthetase (CARS), are essential compounds across many different lifeforms. However, the precise physiological roles of CARS-produced supersulfide are unclear. Now, using a strategically engineered yeast mutant with a deficient CARS gene, researchers from Japan have shown that supersulfides control cell longevity by mediating mitochondrial energy metabolism and regulating protein quality.
Published Cryo-microscopy reveals nano-sized copy machine implicated in origin of life
(via sciencedaily.com) Original source RNA is thought to have sparked the origin of life by self-copying. Researchers have now revealed the atomic structure of an 'RNA copy machine' through cryo-EM. This breakthrough sheds light on a primordial RNA world and fuels advancements in RNA nanotechnology and medicine.
Published The power of pause: Controlled deposition for effective and long-lasting organic devices
(via sciencedaily.com) Original source In organic optoelectronic devices, the control of molecular deposition on thin films is important for optimal surface arrangement and device performance. In a recent study, researchers developed a new method for achieving stable deposition on thin films effectively. They also developed a tool to track real-time potential changes on the surface. These findings are expected to aid the improvement of organic devices, such as organic light-emitting diodes, in terms of efficacy and durability.
Published Bioinformatics: Researchers develop a new machine learning approach
(via sciencedaily.com) Original source To combat viruses, bacteria and other pathogens, synthetic biology offers new technological approaches whose performance is being validated in experiments. Researchers applied data integration and artificial intelligence (AI) to develop a machine learning approach that can predict the efficacy of CRISPR technologies more accurately than before.
Published A novel pathway regulating lipid biosynthesis by fatty acids
(via sciencedaily.com) Original source Sterol regulatory element-binding proteins (SREBPs) play a crucial role in lipid biosynthesis. In a recent study, researchers identified a novel cleavage enzyme of SREBP-1c, a key player in fatty acid biosynthesis. Moreover, the team unveiled, for the first time, that the biosynthesis process of fatty acid in the liver is activated by saturated fatty acids and inhibited by polyunsaturated fatty acids, providing new insights into the intricate workings of this cleavage system.