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Categories: Biology: Molecular, Chemistry: Organic Chemistry
Published Smart skin bacteria are able to secrete and produce molecules to treat acne



An experimental study has shown that a type of skin bacterium can efficiently be engineered to produce a protein to regulate sebum production. This application could treat acne without compromising the homeostasis of the entire skin microbiome.
Published Large-scale mapping of pig genes could pave the way for new human medicines



Researchers have carried out complex genetic analyses of hundreds of pigs and humans to identify differences and similarities. This new knowledge can be used to ensure healthier pigs for farmers and can help the pharmaceutical industry breed better laboratory pigs for testing new medicines.
Published Life span increases in mice when specific brain cells are activated



A new study identifies, in mice, a critical communication pathway connecting the brain and the body's fat tissue in a feedback loop that appears central to energy production throughout the body. The research suggests that the gradual deterioration of this feedback loop contributes to the increasing health problems that are typical of natural aging.
Published Researchers discover molecular 'barcode' used by bacteria to secrete toxins



Researchers have discovered a molecular 'barcode' system used by disease-causing bacteria to distinguish between beneficial and toxic molecules.
Published Important membrane transport mechanism in pathogenic bacteria



Some bacterial membrane transporters work almost like freight elevators to transport substances through the cell membrane into the interior of the cell. The transporter itself spans the bacterial membrane. Like a forklift, a soluble protein outside the bacterium transports the substance to the 'elevator' and unloads its cargo there. The freight elevator transports it to the inside of the cell, in other words to another floor.
Published Revolutionizing stable and efficient catalysts with Turing structures for hydrogen production



Hydrogen energy has emerged as a promising alternative to fossil fuels, offering a clean and sustainable energy source. However, the development of low-cost and efficient catalysts for hydrogen evolution reaction remains a crucial challenge. Scientists have recently developed a novel strategy to engineer stable and efficient ultrathin nanosheet catalysts by forming Turing structures with multiple nanotwin crystals. This innovative discovery paves the way for enhanced catalyst performance for green hydrogen production.
Published Engineers invent octopus-inspired technology that can deceive and signal



With a split-second muscle contraction, the greater blue-ringed octopus can change the size and color of the namesake patterns on its skin for purposes of deception, camouflage and signaling. Researchers have drawn inspiration from this natural wonder to develop a technological platform with similar capabilities for use in a variety of fields, including the military, medicine, robotics and sustainable energy.
Published High-performance stretchable solar cells



Engineers have succeeded in implementing a stretchable organic solar cell by applying a newly developed polymer material that demonstrated the world's highest photovoltaic conversion efficiency (19%) while functioning even when stretched for more than 40% of its original state. This new conductive polymer has high photovoltaic properties that can be stretched like rubber. The newly developed polymer is expected to play a role as a power source for next-generation wearable electronic devices.
Published New roles for autophagy genes in cellular waste management and aging



Autophagy, which declines with age, may hold more mysteries than researchers previously suspected. Scientists have now uncovered possible novel functions for various autophagy genes, which may control different forms of disposal including misfolded proteins -- and ultimately affect aging.
Published The surprisingly resourceful ways bacteria thrive in the human gut



New research shows that some groups of bacteria in the gut are amazingly resourceful, with a large repertoire of genes that help them generate energy for themselves and potentially influence human health as well.
Published Scientists solve mystery of how predatory bacteria recognizes prey



A decades-old mystery of how natural antimicrobial predatory bacteria are able to recognize and kill other bacteria may have been solved, according to new research.
Published Nematode proteins shed light on infertility



Biologists developed a method for illuminating the intricate interactions of the synaptonemal complex in the nematode C. elegans. The authors identified a trio of protein segments that guide chromosomal interactions, and pinpointed the location where they interact with each other. Their novel method uses a technique known as genetic suppressor screening, which can serve as a blueprint for research on large cellular assemblies that resist traditional structural analysis.
Published Study reveals clues to how Eastern equine encephalitis virus invades brain cells



Researchers have determined how Eastern equine encephalitis virus attaches to a receptor it uses to enter and infect cells. The findings laid the groundwork for a receptor decoy molecule that protects mice from encephalitis caused by the virus.
Published Bacteria load their syringes



Many bacterial pathogens use small injection apparatuses to manipulate the cells of their hosts, such as humans, so that they can spread throughout the body. To do this, they need to fill their syringes with the relevant injection agent. A technique that tracks the individual movement of proteins revealed how bacteria accomplish this challenging task.
Published New reasons eating less fat should be one of your resolutions



A new study to motivate your New Year's resolutions: it demonstrates that high-fat diets negatively impact genes linked not only to obesity, colon cancer and irritable bowels, but also to the immune system and brain function.
Published Using electricity, scientists find promising new method of boosting chemical reactions



Chemists found a way to use electricity to boost a type of chemical reaction often used in synthesizing new candidates for pharmaceutical drugs. The research is an advance in the field of electrochemistry and shows a path forward to designing and controlling reactions -- and making them more sustainable.
Published New method illuminates druggable sites on proteins



Scientists develop a new, high-resolution technique for finding potential therapeutic targets on proteins in living cells. The findings could lead to more targeted therapeutics for nearly any human disease.
Published Elusive cytonemes guide neural development, provide signaling 'express route'



Discover the first images of cytonemes during mammalian neural development, serving as express routes to establish morphogen gradients and tissue patterning.
Published Aptamers: lifesavers; ion shields: aptamer guardians



Aptamers, nucleic acids capable of selectively binding to viruses, proteins, ions, small molecules, and various other targets, are garnering attention in drug development as potential antibody substitutes for their thermal and chemical stability as well as ability to inhibit specific enzymes or target proteins through three-dimensional binding. They also hold promise for swift diagnoses of colon cancer and other challenging diseases by targeting elusive biomarkers. Despite their utility, these aptamers are susceptible to easy degradation by multiple enzymes, presenting a significant challenge.
Published First step towards synthetic CO2 fixation in living cells



Three modules forming a new-to-nature CO2 fixation cycle have been successfully implemented in E.coli.