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Categories: Biology: Molecular, Chemistry: Organic Chemistry
Published Solar-powered device produces clean water and clean fuel at the same time



A floating, solar-powered device that can turn contaminated water or seawater into clean hydrogen fuel and purified water, anywhere in the world, has been developed by researchers.
Published The mystery of phosphite -- a scientific detective story



Biologists have discovered a phosphorus-based bacterial metabolism that is both new and ancient. In a special role: a calculation from the 1980s, a sewage plant, a new bacterial organism, and a remnant from around 2.5 billion years ago.
Published Yeast cells can produce drugs for treatment of psychotic disorders



An international team of researchers has demonstrated that genetically engineered yeast cells can produce the natural plant product alstonine, which has shown positive effects in treating schizophrenia.
Published How to use AI for discovery -- without leading science astray



In the same way that chatbots sometimes 'hallucinate,' or make things up, machine learning models designed for scientific applications can sometimes present misleading or downright false results. Researchers now present a new statistical technique for safely using AI predictions to test scientific hypotheses.
Published Team creates synthetic enzymes to unravel molecular mysteries



A bioengineer has developed synthetic enzymes that can control the behavior of the signaling protein Vg1, which plays a key role in the development of muscle, bone and blood in vertebrate embryos. The team of researchers is using a new approach, called the Synthetic Processing (SynPro) system, in zebrafish to study how Vg1 is formed. By learning the molecular rules of signal formation in a developing animal, researchers aim to engineer mechanisms -- such as giving cells new instructions -- that could play a role in treating or preventing disease.
Published Chemists image basic blocks of synthetic polymers



Researchers have developed a new method to image polymerization catalysis reactions one monomer at a time.
Published Scientists use quantum biology, AI to sharpen genome editing tool



Scientists used their expertise in quantum biology, artificial intelligence and bioengineering to improve how CRISPR Cas9 genome editing tools work on organisms like microbes that can be modified to produce renewable fuels and chemicals.
Published First live birth of a chimeric monkey using embryonic stem cell lines



A team of researchers has reported for the first time the live birth of a monkey that contains a high proportion of cells derived from a monkey stem cell line. This 'chimeric' monkey is composed of cells that originate from two genetically distinct embryos of the same species of monkey. This has previously been demonstrated in rats and mice but, until now, has not been possible in other species, including non-human primates.
Published Liquid metals shake up century-old chemical engineering processes



Liquid metals could be the long-awaited solution to 'greening' the chemical industry, according to researchers who tested a new technique they hope can replace energy-intensive chemical engineering processes harking back to the early 20th century.
Published Zen and the art of mitochondrial maintenance: The machinery of death makes a healthier life



While we all aspire for a long lifespan, what is most coveted is a long period of vigor and health, or 'healthspan,' that precedes the inevitable decline of advancing age. Researchers have discovered that instruments of death that cells use to commit suicide when things go wrong contribute to making a longer and healthier life by revitalizing the specialized cellular compartments called mitochondria.
Published Temperature increase triggers viral infection



Researchers have mapped on an atomic level what happens in a virus particle when the temperature is raised.
Published Yeast with an over half synthetic genome is created in the lab



Researchers have combined over seven synthetic chromosomes that were made in the lab into a single yeast cell, resulting in a strain with more than 50% synthetic DNA that survives and replicates similarly to wild yeast strains. A global consortium is working to develop the first synthetic eukaryote genome from scratch. The team has now synthesized and debugged all sixteen yeast chromosomes.
Published Scientists one step closer to re-writing world's first synthetic yeast genome, unravelling the fundamental building blocks of life



Scientists have engineered a chromosome entirely from scratch that will contribute to the production of the world's first synthetic yeast.
Published Scientists take major step towards completing the world's first synthetic yeast



A team of Scientists has completed construction of a synthetic chromosome as part of a major international project to build the world's first synthetic yeast genome. The work represents completion of one of the 16 chromosomes of the yeast genome, which is part of the biggest project ever in synthetic biology; the international synthetic yeast genome collaboration. The collaboration, known as 'Sc2.0' has been a 15-year project involving teams from around the world (UK, US, China, Singapore, UK, France and Australia), working together to make synthetic versions of all of yeast's chromosomes. Alongside this paper, another 9 publications are also released today from other teams describing their synthetic chromosomes. The final completion of the genome project -- the largest synthetic genome ever -- is expected next year.
Published Obesity linked to neurodegeneration through insulin resistance



Researchers have discovered a link between obesity and neurodegenerative disorders like Alzheimer's disease. Using the common fruit fly, the research shows that a high-sugar diet -- a hallmark of obesity -- causes insulin resistance in the brain, which in turn reduces the ability to remove neuronal debris, thus increasing the risk of neurodegeneration.
Published Some benefits of exercise stem from the immune system



Research in mice shows that the anti-inflammatory properties of exercise may arise from immune cells mobilized to counter exercise-induced inflammation. Immune cells prevent muscle damage by lowering levels of interferon, a key driver of chronic inflammation, inflammatory diseases, and aging.
Published Photo battery achieves competitive voltage



Researchers have developed a monolithically integrated photo battery using organic materials. The photo battery achieves an unprecedented high discharge potential of 3.6 volts. The system is capable of powering miniature devices.
Published Charged 'molecular beasts' the basis for new compounds



Mass spectrometers are high-tech machines that play an important role in our society. They are highly sensitive analytical instruments that are indispensable in areas such as medical diagnostics, food quality control and the detection of hazardous chemical substances. A research group is working to modify mass spectrometers so that they can be used for a completely different purpose: the chemical synthesis of new molecules.
Published New antibiotic approach proves promising against lyme bacterium



Using a technique that has shown promise in targeting cancer tumors, a team has found a way to deploy a molecular warhead that can annihilate the bacterium that causes Lyme disease.
Published Visualizing fungal infections deep in living host tissue reveals proline metabolism facilitates virulence



Scientists have published the first successful application of 2-photon intravital microscopy (IVM) to image the dynamics of fungal infections in the kidney of a living host. The study reveals that the opportunistic human fungal pathogen Candida albicans requires the ability to metabolize proline, an amino acid obtained from the host, to mount virulent infections.