Showing 20 articles starting at article 101
< Previous 20 articles Next 20 articles >
Categories: Biology: Molecular, Chemistry: Thermodynamics
Published A new addition to the CRISPR toolbox: Teaching the gene scissors to detect RNA
(via sciencedaily.com) Original source CRISPR-Cas systems, defense systems in bacteria, have become a plentiful source of technologies for molecular diagnostics. Researchers have now expanded this extensive toolbox further. Their novel method, called PUMA, enables the detection of RNA with Cas12 nucleases, which naturally target DNA. PUMA promises a wide range of applications and high accuracy.
Published Unique characteristics of previously unexplored protein discovered
(via sciencedaily.com) Original source Research achieves scientific breakthrough in understanding cell division.
Published Immune system in the spotlight
(via sciencedaily.com) Original source Our immune system is always on alert, detecting and eliminating pathogens and cancer cells. Cellular control mechanisms cause diseased cells to present antigens on their surface like signs for the immune system. For analysis of the necessary complex antigen processing and transport processes in real time, researchers have developed a 'cage' that is opened with light to release trapped antigens at a specific place and time.
Published Capturing carbon with energy-efficient sodium carbonate-nanocarbon hybrid material
(via sciencedaily.com) Original source Carbon capture is a promising approach for mitigating carbon dioxide (CO2) emissions. Different materials have been used to capture CO2 from industrial exhaust gases. Scientists developed hybrid CO2 capture materials containing sodium carbonate and nanocarbon prepared at different temperatures, tested their performance, and identified the optimal calcination temperature condition. They found that the hybrid material exhibits and maintains high CO2 capture capacity for multiple regeneration cycles at a lower temperature, making it cost- and energy-effective.
Published New ways to study spinal cord malformations in embryos
(via sciencedaily.com) Original source Scientists have successfully created mechanical force sensors directly in the developing brains and spinal cords of chicken embryos, which they hope will improve understanding and prevention of birth malformations such as spina bifida.
Published A better way to make RNA drugs
(via sciencedaily.com) Original source RNA drugs are the next frontier of medicine, but manufacturing them requires an expensive and labor-intensive process that limits production and produces metric tons of toxic chemical waste. Researchers report a new, enzyme-based RNA synthesis method that can produce strands of RNA with both natural and modified nucleotides without the environmental hazards.
Published Muscle machine: How water controls the speed of muscle contraction
(via sciencedaily.com) Original source The flow of water within a muscle fiber may dictate how quickly muscle can contract, according to a new study.
Published Nanoplastics and 'forever chemicals' disrupt molecular structures, functionality
(via sciencedaily.com) Original source Researchers have made significant inroads in understanding how nanoplastics and per- and polyfluoroalkyl substances (PFAS) -- commonly known as forever chemicals -- disrupt biomolecular structure and function. The work shows that the compounds can alter proteins found in human breast milk and infant formulas -- potentially causing developmental issues downstream.
Published Hydrogen flight looks ready for take-off with new advances
(via sciencedaily.com) Original source The possibility of hydrogen-powered flight means greater opportunities for fossil-free travel, and the technological advances to make this happen are moving fast. New studies show that almost all air travel within a 750-mile radius (1200 km) could be made with hydrogen-powered aircraft by 2045, and with a novel heat exchanger currently in development, this range could be even further.
Published Opening the right doors: 'Jumping gene' control mechanisms revealed
(via sciencedaily.com) Original source International joint research led by Akihisa Osakabe and Yoshimasa Takizawa of the University of Tokyo has clarified the molecular mechanisms in thale cresses (Arabidopsis thaliana) by which the DDM1 (Decreased in DNA Methylation 1) protein prevents the transcription of 'jumping genes.' DDM1 makes 'jumping genes' more accessible for transcription-suppressing chemical marks to be deposited. Because a variant of this protein exists in humans, the discovery provides insight into genetic conditions caused by such 'jumping gene' mutations.
Published First ever 3D reconstruction of 52,000-year-old woolly mammoth chromosomes thanks to serendipitously freeze-dried skin
(via sciencedaily.com) Original source An international research team has assembled the genome and 3D chromosomal structures of a 52,000-year-old woolly mammoth -- the first time such a feat has been achieved for any ancient DNA sample. The fossilized chromosomes, which are around a million times longer than most ancient DNA fragments, provide insight into how the mammoth's genome was organized within its living cells and which genes were active within the skin tissue from which the DNA was extracted. This unprecedented level of structural detail was retained because the mammoth underwent freeze-drying shortly after it died, which meant that its DNA was preserved in a glass-like state.
Published Atlas of proteins reveals inner workings of cells
(via sciencedaily.com) Original source Researchers discover how proteins behave inside cells using AI, which has the potential to guide drug design.
Published Big gain in battle against harmful bacteria
(via sciencedaily.com) Original source An unexpected find has enabled important progress to be made in the battle against harmful bacteria.
Published Researchers show promising material for solar energy gets its curious boost from entropy
(via sciencedaily.com) Original source Researchers discovered a microscopic mechanism that solves in part the outstanding performance achieved by a new class of organic semiconductors known as non-fullerene acceptors (NFAs).
Published New one-step method to make multiple edits to a cell's genome
(via sciencedaily.com) Original source A team of scientists have developed a new method that enables them to make precise edits in multiple locations within a cell -- all at once. Using molecules called retrons, they created a tool that can efficiently modify DNA in bacteria, yeast, and human cells.
Published New bio-based tool quickly detects concerning coronavirus variants
(via sciencedaily.com) Original source Researchers have developed a bioelectric device that can detect and classify new variants of coronavirus to identify those that are most harmful. It has the potential to do the same with other viruses, as well.
Published GeneMAP discovery platform will help define functions for 'orphan' metabolic proteins
(via sciencedaily.com) Original source Researchers have developed a discovery platform to probe the function of genes involved in metabolism -- the sum of all life-sustaining chemical reactions. The investigators used the new platform, called GeneMAP (Gene-Metabolite Association Prediction), to identify a gene necessary for mitochondrial choline transport.
Published A 2D device for quantum cooling
(via sciencedaily.com) Original source Engineers have created a device that can efficiently convert heat into electrical voltage at temperatures lower than that of outer space. The innovation could help overcome a significant obstacle to the advancement of quantum computing technologies, which require extremely low temperatures to function optimally.
Published Cool roofs are best at beating cities' heat
(via sciencedaily.com) Original source Painting roofs white or covering them with a reflective coating would be more effective at cooling cities like London than vegetation-covered 'green roofs,' street-level vegetation or solar panels, finds a new study led by UCL researchers.
Published Never-before-seen view of gene transcription captured
(via sciencedaily.com) Original source New tech reveals findings that address long-standing theories about how bacteria begin the process of making RNA from DNA.