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Categories: Biology: Molecular, Chemistry: Thermodynamics
Published Do genes-in-pieces code for proteins that fold in pieces?



A new study offers new insights into the evolution of foldable proteins.
Published Researchers uncover key mechanisms in chromosome structure development



Researchers are making strides in understanding how chromosome structures change throughout the cell's life cycle.
Published A new breakthrough in understanding regeneration in a marine worm



The sea worm Platynereis dumerilii is only a few centimeters long but has a remarkable ability: in just a few days, it can regenerate entire parts of its body after an injury or amputation. By focusing more specifically on the mechanisms at play in the regeneration of this worm's tail, a research team has observed that gut cells play a role in the regeneration of the intestine as well as other tissues such as muscle and epidermis.
Published Research shows how RNA 'junk' controls our genes



Researchers have made a significant advance in understanding how genes are controlled in living organisms. The new study focuses on critical snippets of RNA in the tiny, transparent roundworm Caenorhabditis elegans (C. elegans). The study provides a detailed map of the 3'UTR regions of RNA in C. elegans. 3'UTRs (untranslated regions) are segments of RNA involved in gene regulation.
Published Proteins and fats can drive insulin production for some, paving way for tailored nutrition



When it comes to managing blood sugar levels, most people think about counting carbs. But new research shows that, for some, it may be just as important to consider the proteins and fats in their diet. The study is the first large-scale comparison of how different people produce insulin in response to each of the three macronutrients: carbohydrates (glucose), proteins (amino acids) and fats (fatty acids). The findings reveal that production of the blood sugar-regulating hormone is much more dynamic and individualized than previously thought, while showing for the first time a subset of the population who are hyper-responsive to fatty foods.
Published Degradation of cell wall key in the spread of antibiotic resistance



A study provides new clues in the understanding of how antibiotic resistance spreads. The study shows how an enzyme breaks down the bacteria's protective outer layer, the cell wall, and thus facilitates the transfer of genes for resistance to antibiotics.
Published Researchers thwart resistant bacteria's strategy



Bacteria are experts at evolving resistance to antibiotics. One resistance strategy is to cover their cell walls in sticky and gooey biofilm that antibiotics cannot penetrate. A new discovery could put a stop to this strategy.
Published Scientists probe chilling behavior of promising solid-state cooling material



A research team has bridged a knowledge gap in atomic-scale heat motion. This new understanding holds promise for enhancing materials to advance an emerging technology called solid-state cooling.
Published New deep-learning model outperforms Google AI system in predicting peptide structures



Researchers have developed a deep-learning model, called PepFlow, that can predict all possible shapes of peptides -- chains of amino acids that are shorter than proteins, but perform similar biological functions. Peptides are known to be highly flexible, taking on a wide range of folding patterns, and are thus involved in many biological processes of interest to researchers in the development of therapeutics.
Published Common plastics could passively cool and heat buildings with the seasons



By restricting radiant heat flows between buildings and their environment to specific wavelengths, coatings engineered from common materials can achieve energy savings and thermal comfort that goes beyond what traditional building envelopes can achieve.
Published Characterization of the extraordinary thermoelectric properties of cadmium arsenide thin films



If there's one thing we humans are good at, it's producing heat. Significant amounts, and in many cases most of the energy we generate and put into our systems we lose as heat, whether it be our appliances, our transportation, our factories, even our electrical grid.
Published A promising weapon against measles



What happens when measles virus meets a human cell? The viral machinery unfolds in just the right way to reveal key pieces that let it fuse itself into the host cell membrane.
Published Potent therapy candidate for fatal prion diseases



Scientists have developed a gene-silencing tool that shows promise as a therapy against fatal prion diseases. The tool, a streamlined epigenetic editor, paves the way for a new class of genetic approaches to treat certain diseases.
Published New, holistic way to teach synthetic biology



Synthetic biology combines principles from science, engineering and social science, creating emerging technologies such as alternative meats and mRNA vaccines; Deconstructing synthetic biology across scales gives rise to new approach to uniting traditional disciplines; Case studies offer a modular, accessible approach to teaching at different institutions.
Published From takeoff to flight, the wiring of a fly's nervous system is mapped



Although a fly's motor neurons are few, it performs remarkable aerial and terrestrial feats. A wiring diagram recently created of the motor circuits in the central nervous system of the fruit fly is providing detailed information on how the nerve coordination of leg movements differs from that controlling the wings. Such studies reveal the unexpected complexity of the fly's tiny motor system. They also advance the understanding of how the central nervous system in animals coordinates individual muscles to carry out a variety of behaviors.
Published Cell division: Before commitment, a very long engagement



Before a cell commits fully to the process of dividing itself into two new cells, it may ensure the appropriateness of its commitment by staying for many hours -- sometimes more than a day -- in a reversible intermediate state, according to a new discovery. Their revelation of this fundamental feature of biology includes details of its mechanisms and dynamics, which may inform the development of future therapies targeting cancers and other diseases.
Published Unlocking the world of bacteria



Bacteria possess unique traits with great potential for benefiting society. However, current genetic engineering methods to harness these advantages are limited to a small fraction of bacterial species. A team has now introduced a novel approach that can make many more bacteria amenable to genetic engineering. Their method, called IMPRINT, uses cell-free systems to enhance DNA transformation across various bacterial strains.
Published The on-and-off affair in DNA



Researchers have discovered that in thale cresses histone H3 lysine-9 (H3K9) methylation, conventionally thought to be a mark of turning off gene transcription, can also turn on gene expression via the interactions of two other proteins and histone marks. The molecular mechanisms demonstrate that rather than functioning as a simple 'off switch,' H3K9 methylation is more like a 'dimmer switch' that fine-tunes DNA transcription. The discovery suggests there might be similar mechanisms in other organisms, too.
Published Slipping a note to a neighbor: The cellular way



Study reveals how drug molecules bind in channels between neighboring cells, changing intercellular communication.
Published Small, adsorbent 'fins' collect humidity rather than swim through water



Clean, safe water is a limited resource and access to it depends on local bodies of water. But even dry regions have some water vapor in the air. To harvest small amounts of humidity, researchers developed a compact device with absorbent-coated fins that first trap moisture and then generate potable water when heated. They say the prototype could help meet growing demands for water, especially in arid locations.