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Categories: Biology: Molecular, Energy: Nuclear
Published Cells of the future: A key to reprogramming cell identities
(via sciencedaily.com) Original source The intricate process of duplicating genetic information, referred to as DNA replication, lies at the heart of the transmission of life from one cell to another and from one organism to the next. This happens by not just simply copying the genetic information; a well-orchestrated sequence of molecular events has to happen at the right time. Scientists have recently uncovered a fascinating aspect of this process known as 'replication timing' (RT) and how special this is when life commences.
Published Study unveils a role of mitochondria in dietary fat processing
(via sciencedaily.com) Original source Researchers discover a new mechanism controlling the uptake of lipids from digested food.
Published The evolutionary timeline of diminished boric acid and urea transportation in aquaporin 10
(via sciencedaily.com) Original source Aquaporin (Aqp) 10 water channels in humans allow the free passage of water, glycerol, urea, and boric acid across cells. However, Aqp10.2b in pufferfishes allows only the passage of water and glycerol and not urea and boric acid. Researchers sought to understand the evolutionary timeline that resulted in the variable substrate selection mechanisms among Aqp10s. Their results indicate that Aqp10.2 in ray-finned fishes may have reduced or lost urea and boric acid permeabilities through evolution.
Published New study examines the relationship between the rate of wound healing, the circadian rhythm, and 'hair' on cells
(via sciencedaily.com) Original source Nearly every organism on Earth follows a natural circadian rhythm that is coded by your cell's clock genes, which do exactly as you suspect from the name: regulate your body's rhythm on a 24-hour basis. Most cells in mammalian bodies have cilia of some sort, which are hair-like structures that perform a variety of functions such as movement for motile cilia and aiding in structure in function for non-motile, or primary, cilia. The primary cilia also act as a sensory organ for the cell, a function which has illuminated the primary cilia's potential role in the healing process and how bodies heal at a different rate according to our circadian rhythm. In this research, the role of the primary cilia, biological clock and wound healing is explored.
Published Protein allows poison dart frogs to accumulate toxins safely
(via sciencedaily.com) Original source A newly identified protein helps poison dart frogs accumulate and store a potent toxin in their skin which they use for self-defence against predators.
Published Single-celled protists in the guts of animals thrive without the 'powerhouse of the cell'
(via sciencedaily.com) Original source Almost all eukaryotic organisms, from plants and animals to fungi, can't survive without mitochondria -- the 'powerhouses of the cell,' which generate chemical energy using oxygen. However, a new study finds that multiple members of the oxymonads, a group of single-celled protists that live inside the guts of termites and other animals, have evolved to live quite happily without them.
Published Machine learning boosts search for new materials
(via sciencedaily.com) Original source During X-ray diffraction experiments, bright lasers shine on a sample, producing diffracted images that contain important information about the material's structure and properties. But conventional methods of analyzing these images can be contentious, time-consuming, and often ineffective, so scientists are developing deep learning models to better leverage the data.
Published Algae as a surprising meat alternative and source of environmentally friendly protein
(via sciencedaily.com) Original source A new study has demonstrate that the ingestion of two of the most commercially available algal species are rich in protein which supports muscle remodeling in young healthy adults. Their findings suggest that algae may be an interesting and sustainable alternative to animal-derived protein with respect to maintaining and building muscle.
Published New method Ebola virus uses to infect cells
(via sciencedaily.com) Original source Scientists recently published findings indicating that Ebola virus creates and uses intercellular tunnels to move from cell to cell and evade treatments.
Published Genetic atlas detailing early stages of zebrafish development
(via sciencedaily.com) Original source Researchers have published an atlas of zebrafish development, detailing the gene expression programs that are activated within nearly every cell type during the first five days of development, a period in which embryos mature from a single cell into distinct cell types.
Published Acid sensor and calcium store discovered in plants
(via sciencedaily.com) Original source Using optogenetics, researchers have detected a new acid sensor in plant cells that is addressing a cell-internal calcium store.
Published Opportunities to improve future HIV vaccine candidates
(via sciencedaily.com) Original source An effective HIV vaccine may need to prompt strong responses from immune cells called CD8+ T cells to protect people from acquiring HIV, according to a new study. The study findings draw comparisons between the immune system activity of past HIV vaccine study participants and people with HIV who naturally keep the virus from replicating even in the absence of antiretroviral therapy (ART). The latter individuals are often called 'long-term non-progressors' or 'elite controllers' (LTNPs/ECs).
Published Newly developed material gulps down hydrogen, spits it out, protects fusion reactor walls
(via sciencedaily.com) Original source A recent advance could enable more efficient compact fusion reactors that are easier to repair and maintain.
Published How the immune system fights to keep herpes at bay
(via sciencedaily.com) Original source In a study of lab-engineered cells, researchers identify how the immune system neutralizes the herpesvirus. The research maps, for the first time, the maneuvers used by virus and host in the cell nucleus, a poorly understood terrain of host-pathogen interaction. The findings could inform the design of new treatments for herpes and other viruses that replicate in the same way.
Published New understanding of ancient genetic parasite may spur medical breakthroughs
(via sciencedaily.com) Original source Researchers have determined the structure of the most common material in our genomes. New treatments for autoimmune diseases, cancer and neurodegeneration may follow.
Published Enzymes can't tell artificial DNA from the real thing
(via sciencedaily.com) Original source Researchers have come one step closer to unlocking the potential of synthetic DNA, which could help scientists develop never-before-seen proteins in the lab.
Published Scientists unveil complete cell map of a whole mammalian brain
(via sciencedaily.com) Original source Researchers have created a complete cell atlas of a whole mammalian brain. This atlas serves as a map for the mouse brain, describing the type, location, and molecular information of more than 32 million cells and providing information on connectivity between these cells.
Published Cells move in groups differently than they do when alone
(via sciencedaily.com) Original source A protein that helps generate the force needed for single cells to move works differently in cells moving in groups, a new study shows.
Published Extracting uranium from seawater as another source of nuclear fuel
(via sciencedaily.com) Original source Oceans cover most of Earth's surface and support a staggering number of lifeforms, but they're also home to a dilute population of uranium ions. And -- if we can get these particular ions out of the water -- they could be a sustainable fuel source to generate nuclear power. Researchers have now developed a material to use with electrochemical extraction that attracts hard-to-get uranium ions from seawater more efficiently than existing methods.
Published Mice possess natural gene therapy system
(via sciencedaily.com) Original source A previously mysterious small RNA molecule in mice is found to play a crucial role in gene expression, and may be the first identified member of a new class of regulatory RNAs.