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Categories: Biology: Molecular, Energy: Nuclear
Published Humans vs. Bacteria: Differences in ribosome decoding revealed
(via sciencedaily.com) Original source Scientists have found that human ribosomes decode mRNA slower than bacteria, with implications for drug development.
Published Complex assembly process involved in DNA virus replication
(via sciencedaily.com) Original source In a twist on the question, 'Which came first, the chicken or the egg?', scientists have long faced a similar question about how human adenovirus replicates: 'Which comes first, assembly of the viral particle, or packaging of the viral genome?' Now, in a new study, scientists have answered that question, showing that viral proteins use a process called phase separation to coordinate production of viral progeny.
Published How were amino acids, one of the key building blocks of life, formed before the origin of life on Earth?
(via sciencedaily.com) Original source The amino acid abundances of two Ryugu particles were measured and compared with their rocky components. The results demonstrate the important role that water plays in the formation of amino acids on the giant precursors of asteroids like Ryugu. Our solar system formed from a molecular cloud, which was composed of gas and dust that was emitted into the interstellar medium (ISM), a vast space between stars. On collapse of the molecular cloud, the early sun was formed, with a large disk of gas and dust orbiting it. The dusty material collided to produce rocky material that would eventually grow in size to give large bodies called planetesimals.
Published Lab-grown fat could give cultured meat real flavor and texture
(via sciencedaily.com) Original source Researchers have successfully bulk-produced fat tissue in the lab that has a similar texture and make-up to naturally occurring fats from animals.
Published A miniature heart in a petri dish: Organoid emulates development of the human heart
(via sciencedaily.com) Original source A team has induced stem cells to emulate the development of the human heart. The result is a sort of 'mini-heart' known as an organoid. It will permit the study of the earliest development phase of our heart and facilitate research on diseases.
Published Study to decode microbe-gut signaling suggests potential new treatment for IBD
(via sciencedaily.com) Original source Fresh insights into how our bodies interact with the microbes living in our guts suggest that a two-drug combination may offer a new way to treat inflammatory bowel diseases such as Crohn's disease and ulcerative colitis.
Published DELLA proteins could hold key to the next Green Revolution
(via sciencedaily.com) Original source A family of 'promiscuous' proteins found in all land plants is responsible for many different plant functions, despite remaining relatively unchanged for over 450 million years.
Published Cells refine palm fat into olive oil
(via sciencedaily.com) Original source For more than 50 years, it has been suspected that fat cells constantly remodel the lipids they store. Researchers have now demonstrated this process directly for the first time using culture cells. Among other things, the study shows that the cells quickly eliminate harmful fatty acids. They refine others into molecules that can be used more effectively. In the long term, this turns the components of palm fat into the building blocks of high-quality olive oil, for example.
Published Cold is beneficial for healthy aging, at least in animals
(via sciencedaily.com) Original source A lower body temperature is one of the most effective mechanisms to prolong the lifespan of animals. New research has now described precisely how this works. The scientists show that cold can prevent the pathological aggregation of proteins typical for two aging-associated neurodegenerative diseases.
Published Microrobot technology: Externally connecting in vivo neural networks
(via sciencedaily.com) Researchers have developed a technology for delivering a microrobot to a target point of a hippocampus in an in-vitro environment, connecting neural networks, and measuring neural signals. The findings are expected to contribute to neural network research and the verification and analysis of cell therapy products.
Published Form is (mal)function: Protein's shape lets bacteria disarm it
(via sciencedaily.com) Shigella bacteria can infect humans but not mice. A team can now explain why. Their findings may explain the multifariousness of a key weapon of our immune system.
Published Boosting the body's anti-viral immune response may eliminate aging cells
(via sciencedaily.com) Original source Aging cells express a protein that is produced by human cytomegalovirus and is targeted by certain immune cells in the body. Harnessing the immune response to this protein could have multiple health benefits during aging.
Published New details of SARS-COV-2 structure
(via sciencedaily.com) Researchers used computational modeling to reveal finer details surrounding the outer shell of the COVID-19 virus. The work expands the scientific community's understanding of SARS-COV-2, and could lead to more refined antiviral therapies and better vaccines.
Published Scientists see anti-aging potential in an invasive weed
(via sciencedaily.com) Original source The fruit of the cocklebur plant, which grows worldwide and is often considered a noxious weed, has antioxidant and anti-inflammatory components that could make it useful as a skin protectant, according to new research.
Published Cooking up plasmas with microwaves
(via sciencedaily.com) Original source Scientists have created plasmas with fusion-suitable densities, using microwave power with low frequency. The research team has identified three important steps in the plasma production: lightning-like gas breakdown, preliminary plasma production, and steady-state plasma. Blasting the microwaves without alignment of Heliotron J's magnetic field created a discharge that ripped electrons from their atoms and produced an especially dense plasma.
Published How whale shark rhodopsin evolved to see, in the deep blue sea
(via sciencedaily.com) A group of researchers discovered that the rhodopsin -- a protein in the eye that detects light -- of whale sharks has changed to efficiently detect blue light, which penetrates deep-sea water easily. The amino acid substitutions -- one of which is counterintuitively associated with congenital stationary night blindness in humans -- aid in detecting the low levels of light in the deep-sea. Although these changes make the whale shark rhodopsin less thermally stable the deep-sea temperature, allows their rhodopsin to keep working. This suggests that the unique adaptation evolved to function in the low-light low-temperature environment where whale sharks live.
Published Components of cytoskeleton strengthen effect of sex hormones
(via sciencedaily.com) Researchers discover that actin acts in the cell nucleus and is partly responsible for the expression of male sexual characteristics.
Published The powerhouse of the future: Artificial cells
(via sciencedaily.com) Researchers identify the most promising advancements and greatest challenges of artificial mitochondria and chloroplasts. The team describes the components required to construct synthetic mitochondria and chloroplasts and identifies proteins as the most important aspects for molecular rotary machinery, proton transport, and ATP production. The authors believe it is important to create artificial cells with biologically realistic energy-generation methods that mimic natural processes; replicating the entire cell could lead to future biomaterials.
Published Team designs molecule to disrupt SARS-CoV-2 infection
(via sciencedaily.com) A team of scientists designed a molecule that disrupts the infection mechanism of the SARS-CoV-2 coronavirus and could be used to develop new treatments for COVID-19 and other viral diseases.
Published HIV genomes that hide in white blood cells offer new target to eliminate infections
(via sciencedaily.com) To develop treatments that may one day entirely rid the body of HIV infection, scientists have long sought to identify all of the places that the virus can hide its genetic code. Now, in a study using blood samples from men and women with HIV on long-term suppressive therapy, a team of scientists reports new evidence that one such stable reservoir of HIV genomes can be found in circulating white blood cells called monocytes.