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Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular
Published

Starving cells hijack protein transport stations      (via sciencedaily.com)     Original source 

Study details how nutrient-starved cells divert protein transport stations to cellular recycling centers to be broken down, highlighting a novel approach cells use to deal with stressful conditions.

Biology: Biochemistry Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Molecular
Published

Cell's 'garbage disposal' may have another role: Helping neurons near skin sense the environment      (via sciencedaily.com)     Original source 

The typical job of the proteasome, the garbage disposal of the cell, is to grind down proteins into smaller bits and recycle some of those bits and parts. That's still the case, for the most part, but researchers, studying nerve cells grown in the lab and mice, say that the proteasome's role may go well beyond that.

Biology: Biochemistry Biology: Cell Biology Biology: Developmental Biology: Evolutionary Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Ecology: Animals Ecology: Sea Life Environmental: Ecosystems
Published

How seaweed became multicellular      (via sciencedaily.com)     Original source 

A deep dive into macroalgae genetics has uncovered the genetic underpinnings that enabled macroalgae, or 'seaweed,' to evolve multicellularity. Three lineages of macroalgae developed multicellularity independently and during very different time periods by acquiring genes that enable cell adhesion, extracellular matrix formation, and cell differentiation, researchers report. Surprisingly, many of these multicellular-enabling genes had viral origins. The study, which increased the total number of sequenced macroalgal genomes from 14 to 124, is the first to investigate macroalgal evolution through the lens of genomics.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Molecular
Published

Decoding the language of cells: Unveiling the proteins behind cellular organelle communication      (via sciencedaily.com)     Original source 

A collaboration unveils a novel strategy for identifying key proteins in organelle communication. This approach advances our ability to pinpoint proteins essential for organelle interactions within specific spatial and temporal contexts.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Chemistry: Biochemistry Chemistry: Organic Chemistry
Published

Innovative antiviral defense with new CRISPR tool      (via sciencedaily.com)     Original source 

The rise of RNA viruses like SARS-CoV-2 highlights the need for new ways to fight them. RNA-targeting tools like CRISPR/Cas13 are powerful but inefficient in the cytoplasm of cells, where many RNA viruses replicate. Scientists have devised a solution: Cas13d-NCS. This new molecular tool allows CRISPR RNA molecules that are located within the nucleus of a cell to move to the cytoplasm, making it highly effective at neutralizing RNA viruses. This advancement opens doors for precision medicine and proactive viral defense strategies.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

First step to untangle DNA: Supercoiled DNA captures gyrase like a lasso ropes cattle      (via sciencedaily.com)     Original source 

Researchers reveal how DNA gyrase resolves DNA entanglements. The findings not only provide novel insights into this fundamental biological mechanism but also have potential practical applications. Gyrases are biomedical targets for the treatment of bacterial infections and the similar human versions of the enzymes are targets for many anti-cancer drugs. Better understanding of how gyrases work at the molecular level can potentially improve clinical treatments.

Biology: Molecular
Published

Brainless memory makes the spinal cord smarter than previously thought      (via sciencedaily.com)     Original source 

Researchers have discovered the neural circuitry in the spinal cord that allows brain-independent motor learning. The study found two critical groups of spinal cord neurons, one necessary for new adaptive learning, and another for recalling adaptations once they have been learned. The findings could help scientists develop ways to assist motor recovery after spinal cord injury.

Energy: Nuclear Energy: Technology Physics: General
Published

With inspiration from 'Tetris,' researchers develop a better radiation detector      (via sciencedaily.com)     Original source 

A new detector system based on the game 'Tetris' could enable inexpensive, accurate radiation detectors for monitoring nuclear sites.

Biology: Biochemistry Biology: Biotechnology Biology: Botany Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Ecology: Endangered Species
Published

Genetic underpinnings of environmental stress identified in model plant      (via sciencedaily.com)     Original source 

Researchers have identified 14 genes that thale cress -- a plant commonly used in genetic investigations since its genome is well documented -- express more when responding to five specific stressors, as well as eight genes that the plant suppresses.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular
Published

The genesis of our cellular skeleton, image by image      (via sciencedaily.com)     Original source 

Cells contain various specialized structures -- such as the nucleus, mitochondria or peroxisomes -- known as 'organelles'. Tracing their genesis and determining their structure is fundamental to understanding cell function and the pathologies linked to their dysfunction.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular
Published

Researchers discover how we perceive bitter taste      (via sciencedaily.com)     Original source 

A new study reveals the detailed protein structure of the TAS2R14, a bitter taste receptor that allows us to perceive bitter taste. In addition to solving the structure of this taste receptor, the researchers were also able to determine where bitter-tasting substances bind to TAS2R14 and how they activate them. The findings may lead to the development of drugs that targeting taste receptors.

Biology: Biotechnology Biology: Molecular Chemistry: Biochemistry
Published

A new coating method in mRNA engineering points the way to advanced therapies      (via sciencedaily.com)     Original source 

Researchers have developed a novel method of adding polyethylene glycol molecules to engineered groups of messenger RNAs called 'mRNA polyplexes', which enable the cells that receive them to produce specific proteins. This technique allows greater control of the site in the body to which the polyplexes are delivered, significantly advancing the field of therapeutic mRNA technologies, with applications in vaccine development and the treatment of cancer and other diseases.

Chemistry: Biochemistry Chemistry: General Chemistry: Thermodynamics Energy: Technology Environmental: General Geoscience: Geochemistry
Published

New device gathers, stores electricity in remote settings      (via sciencedaily.com)     Original source 

Wirelessly connected devices perform an expanding array of applications, such as monitoring the condition of machinery and remote sensing in agricultural settings. These applications hold much potential for improving the efficiency, but how do you power these devices where reliable electrical sources are not available? Research points to a possible solution in the form of a novel type of battery.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Machine learning method reveals chromosome locations in individual cell nucleus      (via sciencedaily.com)     Original source 

Researchers have made a significant advancement toward understanding how the human genome is organized inside a single cell. This knowledge is crucial for analyzing how DNA structure influences gene expression and disease processes.

Energy: Batteries Energy: Technology
Published

BESSY II: How pulsed charging enhances the service time of batteries      (via sciencedaily.com)     Original source 

An improved charging protocol might help lithium-ion batteries to last much longer. Charging with a high-frequency pulsed current reduces aging effects, an international team demonstrated.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Different means to the same end: How a worm protects its chromosomes      (via sciencedaily.com)     Original source 

Researchers have discovered that a worm commonly used in the study of biology uses a set of proteins unlike those seen in other studied organisms to protect the ends of its DNA.

Biology: Biochemistry Biology: Cell Biology Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Bringing multidrug-resistant pathogens to their knees      (via sciencedaily.com)     Original source 

Multidrug-resistant bacterial infections that cannot be treated by any known antibiotics pose a serious global threat. A research team has now introduced a method for the development of novel antibiotics to fight resistant pathogens. The drugs are based on protein building blocks with fluorous lipid chains.

Energy: Alternative Fuels Energy: Technology Environmental: General Geoscience: Environmental Issues Physics: Optics
Published

New four-terminal tandem organic solar cell achieves 16.94% power conversion efficiency      (via sciencedaily.com)     Original source 

Researchers have fabricated a new four-terminal organic solar cell with a tandem configuration with a 16.94% power conversion efficiency (PCE). The new device is composed by a highly transparent front cell that incorporates a transparent ultrathin silver (Ag) electrode of only 7nm, which ensures its efficient operation.