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Categories: Biology: Molecular, Energy: Technology

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While we all aspire for a long lifespan, what is most coveted is a long period of vigor and health, or 'healthspan,' that precedes the inevitable decline of advancing age. Researchers have discovered that instruments of death that cells use to commit suicide when things go wrong contribute to making a longer and healthier life by revitalizing the specialized cellular compartments called mitochondria.

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Researchers have mapped on an atomic level what happens in a virus particle when the temperature is raised.

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Researchers show that one of the most promising substances for designing longer lasting lithium batteries form micelle-like structures like they do in soap.

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Researchers have combined over seven synthetic chromosomes that were made in the lab into a single yeast cell, resulting in a strain with more than 50% synthetic DNA that survives and replicates similarly to wild yeast strains. A global consortium is working to develop the first synthetic eukaryote genome from scratch. The team has now synthesized and debugged all sixteen yeast chromosomes.

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Scientists have engineered a chromosome entirely from scratch that will contribute to the production of the world's first synthetic yeast.

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A team of Scientists has completed construction of a synthetic chromosome as part of a major international project to build the world's first synthetic yeast genome. The work represents completion of one of the 16 chromosomes of the yeast genome, which is part of the biggest project ever in synthetic biology; the international synthetic yeast genome collaboration. The collaboration, known as 'Sc2.0' has been a 15-year project involving teams from around the world (UK, US, China, Singapore, UK, France and Australia), working together to make synthetic versions of all of yeast's chromosomes. Alongside this paper, another 9 publications are also released today from other teams describing their synthetic chromosomes. The final completion of the genome project -- the largest synthetic genome ever -- is expected next year.

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The rapid adoption of zero-emission electric vehicles will move the nation close to an 80% or more drop in transportation greenhouse gas emissions by 2050 from the 2019 level according to researchers.

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Researchers have discovered a link between obesity and neurodegenerative disorders like Alzheimer's disease. Using the common fruit fly, the research shows that a high-sugar diet -- a hallmark of obesity -- causes insulin resistance in the brain, which in turn reduces the ability to remove neuronal debris, thus increasing the risk of neurodegeneration.

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Researchers have developed an automated laboratory robot to run complex electrochemical experiments and analyze data. The Electrolab will be used to explore next-generation energy storage materials and chemical reactions that promote alternative and sustainable energy.

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One of the largest studies to date finds the current generation of EV owners drive far fewer miles than owners of gas vehicles, translating to lower emissions savings from EVs.

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Researchers found that meeting greenhouse gas emissions goals for light-duty vehicles, which are passenger vehicles such as cars and trucks, is possible, but not just by increasing electric vehicle sales.  

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Research in mice shows that the anti-inflammatory properties of exercise may arise from immune cells mobilized to counter exercise-induced inflammation. Immune cells prevent muscle damage by lowering levels of interferon, a key driver of chronic inflammation, inflammatory diseases, and aging.

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Using a technique that has shown promise in targeting cancer tumors, a team has found a way to deploy a molecular warhead that can annihilate the bacterium that causes Lyme disease.

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Scientists have published the first successful application of 2-photon intravital microscopy (IVM) to image the dynamics of fungal infections in the kidney of a living host. The study reveals that the opportunistic human fungal pathogen Candida albicans requires the ability to metabolize proline, an amino acid obtained from the host, to mount virulent infections.

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A team of researchers has unveiled a first-of-its-kind stable and fully solid-state thermal transistor that uses an electric field to control a semiconductor device's heat movement.  The group's study details how the device works and its potential applications. With top speed and performance, the transistor could open new frontiers in heat management of computer chips through an atomic-level design and molecular engineering. The advance could also further the understanding of how heat is regulated in the human body.

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Researchers have identified a gene which is an early determining factor of ovary development in mice.

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An international team of researchers has discovered that formaldehyde, a widely spread pollutant and common metabolite in our body, interferes in the epigenetic programming of the cell. This finding expands the knowledge of formaldehyde, previously considered only as a DNA mutagen, and helps establishing a further link with cancer.

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Researchers found that the hormone oxytocin, known to be involved in regulating feeding and social behavior and until now to be produced mostly in the brain, is also produced in the human intestine. Furthermore, gut resident bacteria L. reuteri can affect the production of gut-made oxytocin, providing the first insights into a mechanism by which these bacteria can influence human health.

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In the realm of electric vehicles, powered by stored electric energy, the key lies in rechargeable batteries capable of enduring multiple charge cycles. Lithium-ion batteries have been the poster child for this application. However, due to limitations in energy storage capacity and other associated challenges, the focus has shifted to an intriguing alternative known as dual-ion batteries (DIBs).

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In the immune system's fight against cancer and infections, the T cells often lose their power. Now immunologists may have found a possible explanation for this phenomenon.