Showing 20 articles starting at article 421

< Previous 20 articles        Next 20 articles >

Categories: Biology: Molecular, Engineering: Graphene

Return to the site home page

     (via sciencedaily.com)     Original source 

Supersulfides, many of which are produced by cysteinyl-tRNA synthetase (CARS), are essential compounds across many different lifeforms. However, the precise physiological roles of CARS-produced supersulfide are unclear. Now, using a strategically engineered yeast mutant with a deficient CARS gene, researchers from Japan have shown that supersulfides control cell longevity by mediating mitochondrial energy metabolism and regulating protein quality.

     (via sciencedaily.com)     Original source 

A new study presents an innovative graphene-based neurotechnology with the potential for a transformative impact in neuroscience and medical applications.

     (via sciencedaily.com)     Original source 

To combat viruses, bacteria and other pathogens, synthetic biology offers new technological approaches whose performance is being validated in experiments. Researchers applied data integration and artificial intelligence (AI) to develop a machine learning approach that can predict the efficacy of CRISPR technologies more accurately than before.

     (via sciencedaily.com)     Original source 

Sterol regulatory element-binding proteins (SREBPs) play a crucial role in lipid biosynthesis. In a recent study, researchers identified a novel cleavage enzyme of SREBP-1c, a key player in fatty acid biosynthesis. Moreover, the team unveiled, for the first time, that the biosynthesis process of fatty acid in the liver is activated by saturated fatty acids and inhibited by polyunsaturated fatty acids, providing new insights into the intricate workings of this cleavage system.

     (via sciencedaily.com)     Original source 

In a new study, researchers have discovered how a system of proteins, called TamAB, helps Salmonella survive under the harsh conditions inside macrophages.

     (via sciencedaily.com)     Original source 

A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease, researchers report.

     (via sciencedaily.com)     Original source 

Researchers have engineered one of the world's first yeast cells able to harness energy from light, expanding our understanding of the evolution of this trait -- and paving the way for advancements in biofuel production and cellular aging.

     (via sciencedaily.com)     Original source 

Researchers are using crystallography to gain a better understanding of how proteins shapeshift. The knowledge can provide valuable insight into stopping and treating diseases.

     (via sciencedaily.com)     Original source 

A research team investigated how the emergence of the first living systems from inert geological materials happened on the Earth, more than 3.5 billion years ago. Scientists found that by mixing hydrogen, bicarbonate, and iron-rich magnetite under conditions mimicking relatively mild hydrothermal vent results in the formation of a spectrum of organic molecules, most notably including fatty acids stretching up to 18 carbon atoms in length.

     (via sciencedaily.com)     Original source 

The sun has just set on a quiet mudflat in Australia's Northern Territory; it'll set again in another 19 hours. A young moon looms large over the desolate landscape. No animals scurry in the waning light. No leaves rustle in the breeze. No lichens encrust the exposed rock. The only hint of life is some scum in a few puddles and ponds. And among it lives a diverse microbial community of our ancient ancestors.

     (via sciencedaily.com)     Original source 

With human retinas grown in a petri dish, researchers discovered how an offshoot of vitamin A generates the specialized cells that enable people to see millions of colors, an ability that dogs, cats, and other mammals do not possess. The findings increase understanding of color blindness, age-related vision loss, and other diseases linked to photoreceptor cells. They also demonstrate how genes instruct the human retina to make specific color-sensing cells, a process scientists thought was controlled by thyroid hormones.

     (via sciencedaily.com)     Original source 

The repair of damage to genetic material (DNA) in the human body is carried out by highly efficient mechanisms that have not yet been fully researched. A scientific team has now discovered a previously unrecognized control point for these processes. This could lead to a new approach for the development of cancer therapies aimed at inhibiting the repair of damaged cancer cells.

     (via sciencedaily.com)     Original source 

Researchers have developed a neural implant that provides information about activity deep inside the brain while sitting on its surface. The implant is made up of a thin, transparent and flexible polymer strip that is packed with a dense array of graphene electrodes. The technology, tested in transgenic mice, brings the researchers a step closer to building a minimally invasive brain-computer interface (BCI) that provides high-resolution data about deep neural activity by using recordings from the brain surface.

     (via sciencedaily.com)     Original source 

Scientists have succeeded in the stabilization and direct imaging of small clusters of noble gas atoms at room temperature. This achievement opens up exciting possibilities for fundamental research in condensed matter physics and applications in quantum information technology. The key to this breakthrough was the confinement of noble gas atoms between two layers of graphene.

     (via sciencedaily.com)     Original source 

Water samples from 20 sites were tested using a panel of immortalized human cell lines corresponding to the liver, kidney and brain to measure cytotoxicity. Results show that each control toxin induced a consistent pattern of cytotoxicity in the panel of human cell lines assayed. Known toxins were seen only during blooms. Because cell toxicity was seen in the absence of blooms, it suggests that there might be either emergent toxins or a combination of toxins present at those times. Findings suggest that other toxins with the potential to be harmful to human health may be present in the lagoon.

     (via sciencedaily.com)     Original source 

Phosphorus is essential for undisturbed plant growth and development. However, in many soils, phosphorus is only poorly available. One mechanism used by plants to increase phosphorus availability is the release of malate, an organic acid, which can form complexes with iron or aluminium in the soil, thereby liberating sorbed phosphate. However, this response can also result in iron overaccumulation, which can inhibit root growth.

     (via sciencedaily.com)     Original source 

An experimental study has shown that a type of skin bacterium can efficiently be engineered to produce a protein to regulate sebum production. This application could treat acne without compromising the homeostasis of the entire skin microbiome.

     (via sciencedaily.com)     Original source 

Researchers have carried out complex genetic analyses of hundreds of pigs and humans to identify differences and similarities. This new knowledge can be used to ensure healthier pigs for farmers and can help the pharmaceutical industry breed better laboratory pigs for testing new medicines.

     (via sciencedaily.com)     Original source 

A new study identifies, in mice, a critical communication pathway connecting the brain and the body's fat tissue in a feedback loop that appears central to energy production throughout the body. The research suggests that the gradual deterioration of this feedback loop contributes to the increasing health problems that are typical of natural aging.

     (via sciencedaily.com)     Original source 

Researchers have discovered a molecular 'barcode' system used by disease-causing bacteria to distinguish between beneficial and toxic molecules.