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Categories: Biology: Molecular, Engineering: Graphene
Published Membrane transporter ensures mobility of sperm cells
(via sciencedaily.com) Original source Special proteins -- known as membrane transporters -- are key to the mobility of sperm cells. A research team has, with the aid of cryo-electron microscopy, succeeded in decoding the structure of such a transporter and its mechanism. These findings will enable a better understanding of the molecular foundations of reproductive capacity and could, in the long term, contribute to developing new approaches to treating fertility disorders and new methods of specific contraception.
Published Defect in fruit fly respiratory system may provide insights into human aortic aneurysms
(via sciencedaily.com) Original source A team of researchers has gained new insights into the respiratory system of fruit flies -- the so-called tracheal system -- which could be important for future research into aneurysms. Scientists carried out genetic, cell biological and biochemical studies on Drosophila embryos. They found that the cells in the fruit fly's tracheal system are connected to the extracellular matrix by the proteins Dumpy and Piopio.
Published How eggs of the Zika-carrying mosquito survive desiccation
(via sciencedaily.com) Original source Eggs of the mosquito that carries Zika virus can tolerate extended desiccation by altering their metabolism, according to a new study. The finding offers potential new ways to control the spread of this mosquito.
Published Discovery finds ferns produce crop-saving insecticide
(via sciencedaily.com) Original source Researchers have solved the structure of a novel insecticidal protein that is effective in protecting major crop plants like corn and soybean from pests and is naturally produced by ferns.
Published Plants transformed into detectors of dangerous chemicals
(via sciencedaily.com) Original source What if your house plant could tell you your water isn't safe? Scientists are closer to realizing this vision, having successfully engineered a plant to turn beet red in the presence of a banned, toxic pesticide.
Published Moving muscle fibers with magnets 'programs' how they align within tissue
(via sciencedaily.com) Original source Stimulating muscle fibers with magnets causes them to grow in the same direction, aligning muscle cells within tissue. The findings offer a simpler, less time-consuming way for medical researchers to program muscle cell alignment, which is strongly tied to healthy muscle function.
Published How cord-like aggregates of bacteria lead to tuberculosis infections
(via sciencedaily.com) Original source The ability of Mycobacterium tuberculosis (MTB), a serious respiratory infection, to form snake-like cords was first noted nearly 80 years ago. Investigators report the biophysical mechanisms by which these cords form and demonstrate how several generations of dividing bacteria hang together to create these structures that enable resistance to antibiotics.
Published Researchers demonstrate a high-speed electrical readout method for graphene nanodevices
(via sciencedaily.com) Original source Graphene is often referred to as a wonder material for its advantageous qualities. But its application in quantum computers, while promising, is stymied by the challenge of getting accurate measurements of quantum bit states with existing techniques. Now, researchers have developed design guidelines that enable radio-frequency reflectometry to achieve high-speed electrical readouts of graphene nanodevices.
Published Generating clean electricity with chicken feathers
(via sciencedaily.com) Original source Turning unused waste from food production into clean energy: Researchers are using chicken feathers to make fuel cells more cost-effective and sustainable.
Published Physical theory improves protein folding prediction
(via sciencedaily.com) Original source Proteins are important molecules that perform a variety of functions essential to life. To function properly, many proteins must fold into specific structures. However, the way proteins fold into specific structures is still largely unknown. Researchers have developed a novel physical theory that can accurately predict how proteins fold. Their model can predict things previous models cannot. Improved knowledge of protein folding could offer huge benefits to medical research, as well as to various industrial processes.
Published Restoring the function of a human cell surface protein in yeast cells
(via sciencedaily.com) Original source Yeast cells are widely used to study G protein-coupled receptors (GPCRs), a large group of cell surface proteins in humans. However, several of these proteins lose their function when introduced into yeast cells. To tackle this issue, researchers developed an innovative strategy to restore GPCR function in yeast cells by inducing random mutations. Their findings can help understand GPCRs better and could pave the way to therapeutic breakthroughs for many diseases.
Published Soft optical fibers block pain while moving and stretching with the body
(via sciencedaily.com) Original source New soft, implantable fibers can deliver light to major nerves through the body. They are an experimental tool for scientists to explore the causes and potential treatments for peripheral nerve disorders in animal models.
Published Scientists uncover new way viruses fight back against bacteria
(via sciencedaily.com) Original source A microscopic discovery will not only enable scientists to understand the microbial world around us but could also provide a new way to control CRISPR-Cas biotechnologies.
Published From a five-layer graphene sandwich, a rare electronic state emerges
(via sciencedaily.com) Original source When stacked in five layers in a rhombohedral pattern, graphene takes on a rare 'multiferroic' state, exhibiting both unconventional magnetism and an exotic electronic behavior known as ferro-valleytricity.
Published Unlocking the secrets of cell behavior on soft substrates: A paradigm shift in mechanobiology
(via sciencedaily.com) Original source A research group has developed a new method for studying how cancer cells function in softer and stiffer tissue environments. This insight challenges the existing paradigm, opening up new possibilities for research in cancer biology and tissue engineering.
Published Unlocking secrets of immune system proteins: A potential path to new treatments
(via sciencedaily.com) Original source Using cryo-electron microscopy (cryo-EM), researchers captured unprecedented images of key immune system receptors interacting with messenger proteins, elucidating how the receptors change shape upon activation and transmit signals within the cell. The findings suggest new pathways for developing therapeutic molecules for diseases such as COVID-19, rheumatoid arthritis, neurodegenerative diseases and cancer.
Published Boosting weak immune system: Scientists find an unusual weapon against virus
(via sciencedaily.com) Original source Infections with cytomegalovirus (CMV) are extremely common and often pose no major threat to the vast majority of people. They can however be deadly for people whose immune system is weakened, e.g., after bone marrow transplantation. Current treatments against CMV infections are very limited and can have severe side effects. Researchers now propose a new way to protect against CMV. Instead of targeting the virus, their approach boosts the weak immune system and lets it fight the virus on its own.
Published Scientists discover the possible triggers for bacterial pathogens, opening the door for new treatment strategies
(via sciencedaily.com) Original source The legendary Alexander Fleming, who famously discovered penicillin, once said 'never to neglect an extraordinary appearance or happening.' And the path of science often leads to just that. New research is turning the page in our understanding of harmful bacteria and how they turn on certain genes, causing disease in our bodies.
Published Fungal infection in the brain produces changes like those seen in Alzheimer's disease
(via sciencedaily.com) Original source Researchers have discovered how the fungus Candida albicans enters the brain, activates two separate mechanisms in brain cells that promote its clearance, and, important for the understanding of Alzheimer's disease development, generates amyloid beta (Ab)-like peptides, toxic protein fragments from the amyloid precursor protein that are considered to be at the center of the development of Alzheimer's disease.
Published Can't stop binging on fries and BBQ?
(via sciencedaily.com) Original source People overeat and become overweight for a variety of reasons. The fact that flavorful high-calorie food is often available nearly everywhere at any time doesn't help. Researchers have determined for the first time why certain chemicals in cooked or processed foods, called advanced glycation end products, or AGEs, increase hunger and test our willpower or ability to make healthy choices when it comes to food.