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Categories: Biology: Molecular, Engineering: Nanotechnology

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A team has found a way to make the bacterial enzyme histidine kinase water-soluble, which could make it possible to rapidly screen potential antibiotics that might interfere with its functions.

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Why does Hepatitis E become chronic in some patients, and why do medications not work? To find out, an international research team led by scientists from Bochum observed a patient with chronic Hepatitis E infection over a year. Repeated sequencing of the virus RNA showed that the virus incorporated various parts of the host's messenger RNA into its genome. This resulted in a replication advantage, which may have contributed to the infection becoming chronic.

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Academics are often accused of 'splitting hairs', but a team has now devised a machine to do just that. We all have a bad hair day from time to time, and split ends are a common problem. However, the science behind this kind of hair damage is poorly understood, which is why scientists are investigating this knotty problem.

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While smell plays a considerable role in the social interactions of humans -- for instance, signaling fear or generating closeness -- for ants, it is vitally important. Researchers have found that a key protein named Orco, essential for the function of olfactory cells, is also critical for the cells' survival in ants.

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By studying mutations in yeast and human cells, scientists say they have found that biochemical bonds between fats and proteins in the mitochondrion, the cell's powerhouse, play a crucial role in how our cells produce energy.

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Biomedical engineers have developed a silk-based, ultrathin membrane that can be used in organ-on-a-chip models to better mimic the natural environment of cells and tissues within the body. When used in a kidney organ-on-a-chip platform, the membrane helped tissues grow to recreate the functionality of both healthy and diseased kidneys.

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What species live in this coral reef, and are they healthy? Chemical clues emitted by marine organisms might hold that information. But in underwater environments, invisible compounds create a complex 'soup' that is hard for scientists to decipher. Now, researchers have demonstrated a way to extract and identify these indicator compounds in seawater. They found metabolites previously undetected on reefs, including three that may represent different reef organisms.

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Little is yet known about the health effects of nanoparticles on pregnancy. An interdisciplinary team is currently analyzing the risks for babies in the womb. Using a lab model, the researchers were able to determine that certain nanoparticles impair the release of chemical messengers in the placenta and thus the formation of blood vessels.

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Advanced technologies enable the controlled release of medicine to specific cells in the body. Scientists argue these same technologies must be applied to agriculture if growers are to meet increasing global food demands.

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Researchers have been investigating the molecular mechanisms responsible for determining sex in ants. Although the vast majority of an ant colony consists of female workers, males are essential to the continuing survival of the species. In order to uncover the mechanisms involved, the researchers decided to focus on diploid males, which occasionally occur in the Argentine ant.

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Researchers provide the first insight into the mode of action of the lipopeptide serrawettin W2-FL10, derived from Serratia marcescens. This lipopeptide targets the cell membrane of S. aureus, causing lesions which result in the leakage of intracellular components and ultimately cell death.

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Engineers have created a patent-pending method that creates layered perovskite nanowires with exceptionally well-defined and flexible cavities that exhibit a wide range of unusual optical properties beyond conventional perovskites.

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The swirl of milk and espresso -- a small storm in your mug -- doesn't impact the dynamics of the milk proteins, according to research. Researchers took a molecular view of how milk proteins and caffeine molecules interact in water and in a coffee drink. The results suggest that the structures of milk proteins remain intact, meaning they retain their original mouthfeel and taste in your morning brew.

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Researchers invented a technique that allows them to observe which genes and enhancers are active in a cell at the same time. This could help them determine which enhancers control which genes and may reveal potential new drug targets for genetic disorders.

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A recent study provides new insights into how fathers' diets and overweight can affect their children's health even before conception. The findings of the study can help develop preventive health measures for men wishing to become fathers: The healthier the father's diet, the lower the risk for their children to develop obesity or diseases such as diabetes later in life.

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Maternal obesity impacts the eating behaviors of offspring via long-term overexpression of the microRNA miR-505-5p, according to a new study.

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Nanoscale electron transfer (ET) in solids is fundamental to the development of multifunctional materials. However, ET in solids is not yet clearly understood. Now, researchers achieved a direct observation of solid-state ET through X-ray crystal analysis by fabricating a novel double-walled non-covalent crystalline nanotube, which can absorb electron donor molecules and maintain its crystalline structure during ET. This innovative approach can lead to the design of novel functional materials soon.

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Polarized light waves spin clockwise or counterclockwise as they travel, with one direction behaving differently than the other as it interacts with molecules. This directionality, called chirality or handedness, could provide a way to identify and sort specific molecules for use in biomedicine applications, but researchers have had limited control over the direction of the waves -- until now.

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A team of researchers has created a new way to visualize crystals by peering inside their structures, akin to having X-ray vision. Their new technique -- which they aptly named 'Crystal Clear' -- combines the use of transparent particles and microscopes with lasers that allow scientists to see each unit that makes up the crystal and to create dynamic three-dimensional models.

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Team develops a flexible and stretchable device capable of omnidirectional color wavelength control.