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Categories: Biology: Molecular, Engineering: Nanotechnology

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Animals and fungi predominantly use two different modes of cell division -- called open and closed mitosis, respectively. A new study has shown that different species of Ichthyosporea -- marine protists that are close relatives of both animals and fungi -- use either open and closed mitosis, closely correlated to whether the species has multinucleate life cycle stages. The study demonstrates the way animals do cell division might have evolved long before animals themselves did and how this is linked to an organism's life cycle.

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Researchers found that adding a newly developed modified sugar, BNAP-AEO, to gapmer antisense oligonucleotides (ASOs) increased their affinity for target RNAs, thus significantly enhancing their gene-silencing effects in vitro and in vivo. The BNAP-AEO modification also decreased gapmer ASO toxicity to the central nervous system (CNS), suggesting that it could improve the clinical application of ASO treatment of CNS disease.

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Scientists have discovered that when metal is struck by an object moving at a super high velocity, the heat makes the metal stronger. The finding could lead to new approaches to designing materials for extreme environments, such as shields that protect spacecraft or equipment for high-speed manufacturing.

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Researchers have engineered string-like resonators capable of vibrating longer at ambient temperature than any previously known solid-state object -- approaching what is currently only achievable near absolute zero temperatures. Their study pushes the edge of nanotechnology and machine learning to make some of the world's most sensitive mechanical sensors.

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Scientists report a family of tin-based catalysts that efficiently converts CO2 into ethanol, acetic acid and formic acid. These liquid hydrocarbons are among the most produced chemicals in the U.S and are found in many commercial products.

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Two new studies detail the changes seen at the single-cell level in pig organs and recipient human bodies before, during, and just after the xenotransplantation surgeries in the decedents.

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Although periodontitis is an extremely prevalent disorder, it is challenging to conduct detailed and comprehensive analyses of its progression at the cellular level. Recently, researchers developed an improved periodontitis mouse model that simplifies the collection and analysis of multiple periodontal tissue types. Using this model, they clarified the role of an important signaling pathway in the inflammatory response of periodontal tissue, paving the way for better diagnostic and therapeutic strategies for periodontitis.

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Carbon nanotube (CNT) yarns are promising for flexible and fabric-type wearable materials that can convert waste heat into thermoelectricity. To improve the thermoelectric properties of CNT yarns, researchers dispersed CNT filaments in a highly viscous glycerol, enabling the production of CNT yarn with highly aligned bundles together with surfactants that prevent increased thermal conductivity. This innovative approach can significantly improve carbon nanotube-based thermoelectric materials, making it possible to power wearable devices using just body heat.

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Researchers experimentally investigate the impact of introducing high-density calcium on the superconductivity of calcium-intercalated bilayer graphene.

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Scientists have taken a step closer to replicating nature's processes of self-assembly. The study describes the synthetic construction of a tiny, self-assembled crystal known as a 'pyrochlore,' which bears unique optical properties. The advance provides a steppingstone to the eventual construction of sophisticated, self-assembling devices at the nanoscale -- roughly the size of a single virus.

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We are living in a world surrounded by liquid and flow, and understanding the principles that govern its movement is vital in our high-tech world. Through mathematical modeling and experimentation, researchers have expanded on Tanner's Law -- a law in fluid dynamics that describes how non-volatile liquids move across surfaces -- to cover a wider range of volatile liquids. These findings have the potential to play a role in various liquid-based industries such as electronics cooling.

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Scientists have discovered that a protein responsible for the synthesis of a key plant material evolved much earlier than suspected. This new research explored the origin and evolution of the biochemical machinery that builds lignin, a structural component of plant cell walls with significant impacts on the clean energy industry.

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Two-dimensional materials such as graphene promise to form the basis of incredibly small and fast technologies, but this requires a detailed understanding of their electronic properties. New research demonstrates that fast electronic processes can be probed by irradiating the materials with ions first.

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The sweet-taste receptor might be the first stop in a metabolic surveillance system for sugar. The receptor is also expressed in certain intestinal cells, where it may facilitate glucose absorption and assimilation, as part of this system. A team found that stimulation and inhibition of the sweet receptor helps regulate glucose metabolism in humans and may have implications for managing such metabolic disorders as diabetes.

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A paper describes how the moving parts of a particular plant protein control whether plants can grow and make energy-intensive products such as oil -- or instead put in place a series of steps to conserve precious resources. The study focuses specifically on how the molecular machinery is regulated by a molecule that rises and falls with the level of sugar -- plants' main energy source.

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Using DNA origami, researchers have built a diamond lattice with a periodicity of hundreds of nanometers -- a new approach for manufacturing semiconductors for visible light.

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Plants have special corrective molecules at their disposal that can make retrospective modifications to copies of genes. However, it would appear that these 'Tipp-Ex proteins' do not have permission to work in all areas of the cell, only being used in chloroplasts and mitochondria. A study has now explained why this is the case. It suggests that the correction mechanism would otherwise modify copies that have nothing wrong with them, with fatal consequences for the cell.

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If fruit fly wings do not develop into the right shape, the flies will die. Researchers have learned how fly embryo cells develop as they need to, opening a window into human development and possible treatments for birth defects.

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A molecular biologist may have found a new 'rule of biology.' The rule challenges long-held notions that most living organisms prefer stability over instability because stability requires less energy and fewer resources.

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A new sensor is giving researchers the best look yet at ATP levels inside living cells, enabling scientists to study in greater detail than ever before how fluctuations in this cellular currency affect the cell and contribute to disease.