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Categories: Biology: Molecular, Physics: Optics

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Advances in electrochromic coatings may bring us closer to environmentally friendly ways to keep inside spaces cool. Like eyeglasses that darken to provide sun protection, the optical properties of these transparent films can be tuned with electricity to block out solar heat and light. Now, researchers report demonstrating a new electrochromic film design based on metal-organic frameworks (MOFs) that quickly and reliably switch from transparent to glare-diminishing green to thermal-insulating red.

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A new study may help redefine how scientists map the surface of the Moon, making the process more streamlined and precise than ever before.

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Researchers have managed to generate propagating spin waves at the nanoscale and discovered a novel pathway to modulate and amplify them. Their discovery could pave the way for the development of dissipation free quantum information technologies. As the spin waves do not involve electric currents these chips will be free from associated losses of energy. The rapidly growing popularity of artificial intelligence comes with an increasing desire for fast and energy efficient computing devices and calls for novel ways to store and process information. The electric currents in conventional devices suffer from losses of energy and subsequent heating of the environment.

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Participants following an intermittent fasting and protein-pacing regimen, which involves evenly spaced protein intake throughout the day, saw better gut health, weight loss and metabolic responses. These benefits were notably greater than those seen with simple calorie restriction. The findings could advance our understanding of the relationship between the gut microbiome and metabolism and improve strategies for managing obesity.

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Researchers have demonstrated how B cells infected with the Epstein-Barr virus (EBV) can contribute to a pathogenic, inflammatory phenotype that contributes to multiple sclerosis (MS); the group has also shown how these problematic B cells can be selectively targeted in a way that reduces the damaging autoimmune response of multiple sclerosis.

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Scientists have designed a way to 'cloak' proteins in a generalized technique that could lead to repurposing things like antibodies for biological research and therapeutic applications.

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Researchers found that approximately one in 40 human bone marrow cells carry massive chromosomal alterations without causing any apparent disease or abnormality. Even so-called normal cells carry all sorts of genetic mutations, meaning there are more genetic differences between individual cells in our bodies than between different human beings. The discovery was enabled by a single-cell sequencing technology called Strand-seq, a unique DNA sequencing technique that can reveal subtle details of genomes in single cells that are too difficult to detect with other methods.

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Researchers have developed a new technique to view living mammalian cells. The team used a powerful laser, called a soft X-ray free electron laser, to emit ultrafast pulses of illumination at the speed of femtoseconds, or quadrillionths of a second. With this they could capture images of carbon-based structures in living cells for the first time, before the soft X-ray radiation damaged them.

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Many of today's quantum devices rely on collections of qubits, also called spins. These quantum bits have only two energy levels, the '0' and the '1'. However, spins in real devices also interact with light and vibrations known as bosons, greatly complicating calculations. Researchers now demonstrate a way to describe spin-boson systems and use this to efficiently configure quantum devices in a desired state.

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Researchers have fabricated a device no wider than a human hair that will help physicists investigate the fundamental nature of matter and light. Their findings could also support the development of more efficient lasers, which are used in fields ranging from medicine to manufacturing.

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Researchers introduce a polymer-based material with unique properties. This material allows sunlight to enter, maintains a more comfortable indoor climate without additional energy, and cleans itself like a lotus leaf. The new development could replace glass components in walls and roofs in the future.

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Closing in on the theoretical maximum efficiency, devices for turning heat into electricity are edging closer to being practical for use on the grid, according to new research.

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Biologists have provided new insights on a longstanding puzzle in biology: How complex organisms arise from a single fertilized cell. Producing a new 'gene atlas' with 4-D imaging, the researchers captured unprecedented insights on how embryonic development unfolds.

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Multicellular organisms, like animals and plants, have complex cells with diverse functions. This complexity arises from the need for cells to produce distinct proteins that interact with each other. This interaction is crucial for cells to carry out their specific tasks and to form complex molecular machinery. However, our current understanding of such protein-protein interactions often lacks cellular contexts because they were usually studied in an in vitro system or in cells isolated from their tissue environment. Effective methods to investigate protein-protein interactions in a tissue-specific manner are largely missing.

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Treatment of autoimmune diseases like lupus has long relied on steroids to knock down the immune system, but more targeted therapies are currently undergoing clinical trials. To make sure these therapies get to the patients who will benefit, work is needed to identify the specific mutations behind each patient's disease. Researchers now report several dozen mutations associated with oversensitive toll-like receptors -- a major cause of autoimmune disease -- and linked two mutations to patients.

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Scientists have made discoveries about light particles known as photons that could aid the quest for fusion energy.

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Researchers developed a way to help people with amputation or paralysis regain limb control. Their optogenetic technique could offer more precise control over muscle contraction, along with a dramatic decrease in muscle fatigue.

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Animals and fungi predominantly use two different modes of cell division -- called open and closed mitosis, respectively. A new study has shown that different species of Ichthyosporea -- marine protists that are close relatives of both animals and fungi -- use either open and closed mitosis, closely correlated to whether the species has multinucleate life cycle stages. The study demonstrates the way animals do cell division might have evolved long before animals themselves did and how this is linked to an organism's life cycle.

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Researchers found that adding a newly developed modified sugar, BNAP-AEO, to gapmer antisense oligonucleotides (ASOs) increased their affinity for target RNAs, thus significantly enhancing their gene-silencing effects in vitro and in vivo. The BNAP-AEO modification also decreased gapmer ASO toxicity to the central nervous system (CNS), suggesting that it could improve the clinical application of ASO treatment of CNS disease.

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Researchers describe new microcomb lasers they have developed that overcome previous limitations and feature a simple design that could open the door to a broad range of uses.