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Categories: Biology: Molecular, Physics: Optics

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A viral defense mechanism can be used to accelerate the creation of female stem cell lines in mice. The findings can boost efforts in medical research, drug testing, and regenerative therapies, particularly for women and individuals with two X chromosomes.

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In nematodes and humans, mitochondrial stress in the nervous system initiates a whole-body response that is most pronounced in the gut. A recent study showed that in nematodes, the odor of a pathogen triggers the nervous system to broadcast this response to the rest of the organism, prepping mitochondria in intestinal cells to fight a bacterial infection. Humans, too, may be able to sense pathogenic odors that prepare the gut for an infection.

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Researchers have discovered two proteins that work in tandem to control an important response to cell stress.

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Researchers found that how well light-converting molecules stack together in a solid is important for how well they convert light into electric current. A rigid molecule that stacked well showed excellent electricity generation in an organic solar cell and photocatalyst, easily outperforming a similar flexible molecule that did not stack well. This new way of improving the design of molecules could be used to pioneer the next generation of light-converting devices.

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Using state of the art techniques, researchers use vibrations from traffic to measure underground soil moisture.

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Researchers have discovered a new population of macrophages, important innate immune cells that populate the lungs after injury caused by respiratory viruses. These macrophages are instrumental in repairing the pulmonary alveoli. This groundbreaking discovery promises to revolutionize our understanding of the post-infectious immune response and opens the door to new regenerative therapies.

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Scientists found that decreasing folate intake can support healthier metabolisms in aging animal models, challenging the conventional belief that high folate consumption universally benefits health.

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The process by which phages -- viruses that infect and replicate within bacteria -- enter cells has been studied for over 50 years. In a new study, researchers have used cutting-edge techniques to look at this process at the level of a single cell.

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The origins of life remain a major mystery. How were complex molecules able to form and remain intact for prolonged periods without disintegrating? A team has demonstrated a mechanism that could have enabled the first RNA molecules to stabilize in the primordial soup. When two RNA strands combine, their stability and lifespan increase significantly.

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Wild boars and red junglefowl gave rise to common pigs and chickens. These animals' genes evolved to express themselves differently, leading to signatures of domestication -- such as weaker bones and better viral resistance -- in pigs and chickens, according to a research team.

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Researchers have developed new real-time microscopy technology and successfully observed the behavior of 'motor proteins', which may hold the key to unraveling the efficient material transport strategy of cells.

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Scientists have hypothesized that moir excitons -- electron-hole pairs confined in moir interference fringes which overlap with slightly offset patterns -- may function as qubits in next-generation nano-semiconductors. However, due to diffraction limits, it has not been possible to focus light enough in measurements, causing optical interference from many moir excitons. To solve this, researchers have developed a new method of reducing these moir excitons to measure the quantum coherence time and realize quantum functionality.

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Scientists uncover a pivotal enzyme, XccOpgD, and its critical role in synthesizing C G16, a key compound used by Xanthomonas pathogens to enhance their virulence against plants. This breakthrough opens new avenues for developing targeted pesticides that combat plant diseases without harming beneficial organisms. Insights into XccOpgD's enzymatic mechanism and optimal conditions offer promising prospects for sustainable agriculture, bolstering crop resilience and global food security while minimizing environmental impact.

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Researchers transferred genes from simple organisms capable of regenerating their bodies into common fruit flies, more complex animals that cannot. They found the transferred gene suppressed an age-related intestinal issue in the flies. Their results suggest studying genes specific to animals with high regenerative capability may uncover new mechanisms for rejuvenating stem cell function and extending the healthy lifespan of unrelated organisms.

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An international research team has succeeded in developing a new version of RNA building blocks with higher chemical reactivity and photosensitivity. This can significantly reduce the production time of RNA chips used in biotechnological and medical research. The chemical synthesis of these chips is now twice as fast and seven times more efficient.

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Researchers have succeeded in identifying and synthesizing a group of molecules that can act against the cause of tuberculosis in a new way. They describe that the so-called callyaerins act against the infectious disease by employing a fundamentally different mechanism compared to antibiotic agents used to date.

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A coating of solar cells with special organic molecules could pave the way for a new generation of solar panels. This coating can increase the efficiency of monolithic tandem cells made of silicon and perovskite while lowering their cost -- because they are produced from industrial, microstructured, standard silicon wafers.

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Physicists have experimentally demonstrates a novel physical effect that was predicted 45 years ago. The effect will result in a new chemical analysis technique, to simultaneously identify molecular bonds and their 3D arrangement in space. This new technique will find applications in pharmaceutical science, security, forensics, environmental science, art conservation, and medicine.

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Hydrogen can be produced via the electrolytic splitting of water. One option here is the use of photoelectrodes that convert sunlight into voltage for electrolysis in so called photoelectrochemical cells (PEC cells). A research team has now shown that the efficiency of PEC cells can be significantly increased under pressure.

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Using powerful new visualization technologies, researchers have captured the first 3-D images of the structure of a key muscle receptor, providing new insights on how muscles develop across the animal kingdom and setting the stage for possible future treatments for muscular disorders.