Showing 20 articles starting at article 1121

< Previous 20 articles        Next 20 articles >

Categories: Biology: Molecular, Computer Science: General

Return to the site home page

     (via sciencedaily.com)     Original source 

An AI strategy proven adept at board games like Chess and Go, reinforcement learning, has now been adapted for a powerful protein design program. The results show that reinforcement learning can do more than master board games. When trained to solve long-standing puzzles in protein science, the software excelled at creating useful molecules. In one experiment, proteins made with the new approach were found to be more effective at generating useful antibodies in mice than were previous methods. If this method is applied to the right research problems, it likely could accelerate progress in a variety of scientific fields.

     (via sciencedaily.com)     Original source 

A new machine-learning system can generate protein designs with certain structural features, and which do not exist in nature. These proteins could be utilized to make materials that have similar mechanical properties to existing materials, like polymers, but which would have a much smaller carbon footprint.

     (via sciencedaily.com)     Original source 

Investigators are developing a novel way to treat amyotrophic lateral sclerosis (ALS) and retinitis pigmentosa using engineered stem cells that may eventually lead to personalized treatments.

     (via sciencedaily.com)     Original source 

Recently quantum computers started to work with more than just the zeros and ones we know from classical computers. Now a team demonstrates a way to efficiently create entanglement of such high-dimensional systems to enable more powerful calculations.

     (via sciencedaily.com)     Original source 

There are high expectations that quantum computers may deliver revolutionary new possibilities for simulating chemical processes. This could have a major impact on everything from the development of new pharmaceuticals to new materials. Researchers have now used a quantum computer to undertake calculations within a real-life case in chemistry.

     (via sciencedaily.com)     Original source 

5G signals known as millimeter-wave carry enormous amounts of information but are very easy to block. A new device helps these signals get around obstacles posed by walls, furniture and people.

     (via sciencedaily.com)     Original source 

What if, by adding a couple of cell layers inside a corn kernel, the grain could become significantly richer in essential nutrients like iron, zinc, and protein? Such an improvement could benefit people who rely on corn for a large portion of their diet, as in many parts of the global south.

     (via sciencedaily.com)     Original source 

Certain stem cells have a unique ability to move between growth compartments in hair follicles, but get stuck as people age and so lose their ability to mature and maintain hair color, a new study shows.

     (via sciencedaily.com)     Original source 

Two protein complexes carry the major responsibility for the spatial organization of chromosomes in our cell nuclei. DNA tension plays a surprising role in this. Nanoscientists now publish how they have visualized this.

     (via sciencedaily.com)     Original source 

A hitherto unknown mechanism for DNA folding is described in a new study. The findings provide new insights into chromosomal processes that are vital to both normal development and to prevent disease.

     (via sciencedaily.com)     Original source 

Small interfering RNAs (siRNAs) are novel therapeutics that can be used to treat a wide range of diseases. This has led to a growing demand for selective, efficient, and safe ways of delivering siRNA in cells. Now, in a cooperation between the Universities of Amsterdam and Leiden, researchers have developed dedicated molecular nanocages for siRNA delivery. In a paper just out in the Journal Chem they present nanocages that are easy to prepare and display tuneable siRNA delivery characteristics.

     (via sciencedaily.com)     Original source 

A team has shown in the laboratory the unique and practical function of newly created materials, which they called quantum composites, that may advance electrical, optical, and computer technologies.

     (via sciencedaily.com)     Original source 

Scientists can now use light to activate protein functions both inside and outside of living cells. The new method, called light-activated SpyLigation, can turn on proteins that are normally off to allow researchers to study and control them in more detail. This technology has potential uses in tissue engineering, regenerative medicine, and understanding how the body works. The scientists applied their new method to control the glow of a green fluorescent protein derived from Japanese eel muscle.

     (via sciencedaily.com)     Original source 

A species of ordinary gut bacteria that we all carry flourishes when the intestinal flora is knocked out by a course of antibiotics. Since the bacteria is naturally resistant to many antibiotics, it causes problems, particularly in healthcare settings. A study now shows how two molecular mechanisms can work together make the bacterium extra resistant.

     (via sciencedaily.com)     Original source 

Research has traced the evolutionary adaptations of octopus and squid sensing capabilities. The researchers describe for the first time the structure of an octopus chemotactile receptor, which octopus arms use for taste-by-touch exploration of the seafloor.

     (via sciencedaily.com)     Original source 

Researchers describe how the Epstein-Barr virus exploits genomic weaknesses to cause cancer while reducing the body's ability to suppress it.

     (via sciencedaily.com)     Original source 

Origin-of-life chemists propose that glyoxylate could have been the original source of sugars on the 'prebiotic' Earth

     (via sciencedaily.com)     Original source 

A research team has recently made a significant discovery about the evolutionary age of different type of cells in a small animal called Caenorhabditis elegans (C. elegans). By using single-cell transcriptomic data and refined phylostratigraphy, the team determines the transcriptomic age of individual cells, which means they are able to estimate the evolutionary origin of different cells based on the age of the genes expressed in the cells.

     (via sciencedaily.com)     Original source 

In a series of experiments, a team of researchers have compared de novo proteins with random-sequence proteins, looking at their stability and solubility. The results are set to advance basic research in this new field.

     (via sciencedaily.com)     Original source 

Acylceramides and protein-bound ceramides are vital for the formation of the oral barrier in mice, similar to their role in skin, protecting from infection.