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Categories: Biology: Molecular, Computer Science: General
Published The enemy within: How pathogens spread unrecognized in the body
(via sciencedaily.com) Original source Some pathogens hide inside human cells to enhance their survival. Researchers have uncovered a unique tactic certain bacteria use to spread in the body without being detected by the immune system. In their study, they reveal the crucial role of a bacterial nanomachine in this infection process.
Published Breakthrough rice bran nanoparticles show promise as affordable and targeted anticancer agent
(via sciencedaily.com) Original source Plant-derived nanoparticles have demonstrated significant anticancer effects. Researchers recently developed rice bran-derived nanoparticles (rbNPs) that efficiently suppressed cell proliferation and induced programmed cell death of only cancer cells. Furthermore, rbNPs successfully suppressed the growth of tumors in mice having aggressive adenocarcinoma in their peritoneal cavity, without any adverse effects. Given their low production costs and high efficacy, rbNPs hold great promise for developing affordable and safe anticancer agents.
Published Key protein regulates immune response to viruses in mammal cells
(via sciencedaily.com) Original source Researchers have revealed the regulatory mechanism of a specific protein, TRBP, that plays a key role in balancing the immune response triggered by viral infections in mammal cells. These findings could help drive the development of antiviral therapies and nucleic acid medicines to treat genetic disorders.
Published Accelerating the discovery of new materials via the ion-exchange method
(via sciencedaily.com) Original source Researchers have unveiled a new means of predicting how to synthesize new materials via the ion-exchange. Based on computer simulations, the method significantly reduces the time and energy required to explore for inorganic materials.
Published Light show in living cells
(via sciencedaily.com) Original source Observing proteins precisely within cells is extremely important for many branches of research but has been a significant technical challenge -- especially in living cells, as the required fluorescent labeling had to be individually attached to each protein. The research group has now overcome this hurdle: With a method called 'vpCells,' it is possible to label many proteins simultaneously, using five different fluorescent colors.
Published Why can zebrafish regenerate damaged heart tissue, while other fish species cannot?
(via sciencedaily.com) Original source A heart attack will leave a permanent scar on a human heart, yet other animals, including zebrafish, can clear cardiac scar tissue and regrow damaged muscle as adults. Biologists sheds new light on how zebrafish heal heart tissue by comparing how this species responds to heart injury with medaka, a fish species that cannot regenerate cardiac tissue.
Published Teaching a computer to type like a human
(via sciencedaily.com) Original source A new typing model simulates the typing process instead of just predicting words.
Published Skyrmions move at record speeds: A step towards the computing of the future
(via sciencedaily.com) Original source Scientists have discovered that the magnetic nanobubbles known as skyrmions can be moved by electrical currents, attaining record speeds up to 900 m/s. Anticipated as future bits in computer memory, these nanobubbles offer enhanced avenues for information processing in electronic devices. Their tiny size provides great computing and information storage capacity, as well as low energy consumption. Until now, these nanobubbles moved no faster than 100 m/s, which is too slow for computing applications. However, thanks to the use of an antiferromagnetic material as medium, the scientists successfully had the skyrmions move 10 times faster than previously observed. These results offer new prospects for developing higher-performance and less energy-intensive computing devices.
Published RNA's hidden potential: New study unveils its role in early life and future bioengineering
(via sciencedaily.com) Original source The origin of life continues to remain a matter of debate. The ribonucleic acid (RNA) world hypothesis proposes that 'ribozymes' which store genetic information and possess catalytic functions may have supported the activities of early life forms. Now, researchers explore how RNA elongation is regulated allosterically, shedding light on its impact on early life processes and offering insights into the fabrication of arbitrary RNA nanostructures with various modern applications.
Published How 3D printers can give robots a soft touch
(via sciencedaily.com) Original source Soft skin coverings and touch sensors have emerged as a promising feature for robots that are both safer and more intuitive for human interaction, but they are expensive and difficult to make. A recent study demonstrates that soft skin pads doubling as sensors made from thermoplastic urethane can be efficiently manufactured using 3D printers.
Published Solving a mini mystery of cell division
(via sciencedaily.com) Original source Trying to hit a target size before dividing seems like the best strategy for maintaining a precise cell size, but bacteria don't do that. Now we know why.
Published Plant sensors could act as an early warning system for farmers
(via sciencedaily.com) Original source Using a pair of sensors made from carbon nanotubes, researchers discovered signals that help plants respond to stresses such as heat, light, or attack from insects or bacteria. Farmers could use these sensors to monitor threats to their crops, allowing them to intervene before the crops are lost.
Published Tracking a protein's fleeting shape changes
(via sciencedaily.com) Original source Researchers have developed a powerful, new technique to generate 'movies' of changing protein structures and speeds of up to 50 frames per second.
Published Researchers uncover human DNA repair by nuclear metamorphosis
(via sciencedaily.com) Original source Researchers have discovered a DNA repair mechanism that advances understanding of how human cells stay healthy, and which could lead to new treatments for cancer and premature aging.
Published How blue-green algae manipulate microorganisms
(via sciencedaily.com) Original source A research team discovers previously unknown gene that indirectly promotes photosynthesis Protein regulator NirP1 influences the coordination of the nitrogen and carbohydrate metabolism 'Such protein regulators could in future be deployed in 'green' and 'blue' biotechnology for targeted control of the metabolism,' says geneticist.
Published Unlocking the 'chain of worms'
(via sciencedaily.com) Original source An international team of scientists has published a single-cell atlas for Pristina leidyi (Pristina), the water nymph worm, a segmented annelid with extraordinary regenerative abilities that has fascinated biologists for more than a century.
Published Millions of gamers advance biomedical research
(via sciencedaily.com) Original source 4.5 million gamers around the world have advanced medical science by helping to reconstruct microbial evolutionary histories using a minigame included inside the critically and commercially successful video game, Borderlands 3. Their playing has led to a significantly refined estimate of the relationships of microbes in the human gut. The results of this collaboration will both substantially advance our knowledge of the microbiome and improve on the AI programs that will be used to carry out this work in future.
Published Starving cells hijack protein transport stations
(via sciencedaily.com) Original source Study details how nutrient-starved cells divert protein transport stations to cellular recycling centers to be broken down, highlighting a novel approach cells use to deal with stressful conditions.
Published Cell's 'garbage disposal' may have another role: Helping neurons near skin sense the environment
(via sciencedaily.com) Original source The typical job of the proteasome, the garbage disposal of the cell, is to grind down proteins into smaller bits and recycle some of those bits and parts. That's still the case, for the most part, but researchers, studying nerve cells grown in the lab and mice, say that the proteasome's role may go well beyond that.
Published How seaweed became multicellular
(via sciencedaily.com) Original source A deep dive into macroalgae genetics has uncovered the genetic underpinnings that enabled macroalgae, or 'seaweed,' to evolve multicellularity. Three lineages of macroalgae developed multicellularity independently and during very different time periods by acquiring genes that enable cell adhesion, extracellular matrix formation, and cell differentiation, researchers report. Surprisingly, many of these multicellular-enabling genes had viral origins. The study, which increased the total number of sequenced macroalgal genomes from 14 to 124, is the first to investigate macroalgal evolution through the lens of genomics.