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Categories: Biology: Molecular, Computer Science: General

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Scientists have summarized microbial food production strategies.

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A collaboration unveils a novel strategy for identifying key proteins in organelle communication. This approach advances our ability to pinpoint proteins essential for organelle interactions within specific spatial and temporal contexts.

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The rise of RNA viruses like SARS-CoV-2 highlights the need for new ways to fight them. RNA-targeting tools like CRISPR/Cas13 are powerful but inefficient in the cytoplasm of cells, where many RNA viruses replicate. Scientists have devised a solution: Cas13d-NCS. This new molecular tool allows CRISPR RNA molecules that are located within the nucleus of a cell to move to the cytoplasm, making it highly effective at neutralizing RNA viruses. This advancement opens doors for precision medicine and proactive viral defense strategies.

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A team of computer scientists working on two different problems -- how to quickly detect damaged buildings in crisis zones and how to accurately estimate the size of bird flocks -- recently announced an AI framework that can do both. The framework, called DISCount, blends the speed and massive data-crunching power of artificial intelligence with the reliability of human analysis to quickly deliver reliable estimates that can quickly pinpoint and count specific features from very large collections of images.

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Researchers reveal how DNA gyrase resolves DNA entanglements. The findings not only provide novel insights into this fundamental biological mechanism but also have potential practical applications. Gyrases are biomedical targets for the treatment of bacterial infections and the similar human versions of the enzymes are targets for many anti-cancer drugs. Better understanding of how gyrases work at the molecular level can potentially improve clinical treatments.

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Researchers have discovered the neural circuitry in the spinal cord that allows brain-independent motor learning. The study found two critical groups of spinal cord neurons, one necessary for new adaptive learning, and another for recalling adaptations once they have been learned. The findings could help scientists develop ways to assist motor recovery after spinal cord injury.

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New research suggests that materials commonly overlooked in computer chip design actually play an important role in information processing, a discovery which could lead to faster and more efficient electronics. Using advanced imaging techniques, an international team found that the material that a semiconductor chip device is built on, called the substrate, responds to changes in electricity much like the semiconductor on top of it.

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The full power of next-generation quantum computing could soon be harnessed by millions of individuals and companies, thanks to a breakthrough guaranteeing security and privacy. This advance promises to unlock the transformative potential of cloud-based quantum computing.

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Researchers have identified 14 genes that thale cress -- a plant commonly used in genetic investigations since its genome is well documented -- express more when responding to five specific stressors, as well as eight genes that the plant suppresses.

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A new technique can more effectively perform a safety check on an AI chatbot. Researchers enabled their model to prompt a chatbot to generate toxic responses, which are used to prevent the chatbot from giving hateful or harmful answers when deployed.

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Cells contain various specialized structures -- such as the nucleus, mitochondria or peroxisomes -- known as 'organelles'. Tracing their genesis and determining their structure is fundamental to understanding cell function and the pathologies linked to their dysfunction.

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A new study reveals the detailed protein structure of the TAS2R14, a bitter taste receptor that allows us to perceive bitter taste. In addition to solving the structure of this taste receptor, the researchers were also able to determine where bitter-tasting substances bind to TAS2R14 and how they activate them. The findings may lead to the development of drugs that targeting taste receptors.

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Researchers have developed a novel method of adding polyethylene glycol molecules to engineered groups of messenger RNAs called 'mRNA polyplexes', which enable the cells that receive them to produce specific proteins. This technique allows greater control of the site in the body to which the polyplexes are delivered, significantly advancing the field of therapeutic mRNA technologies, with applications in vaccine development and the treatment of cancer and other diseases.

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Researchers decode repair mechanism during transcription of genetic information.

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When scuba divers need to say 'I'm okay' or 'Shark!' to their dive partners, they use hand signals to communicate visually. But sometimes these movements are difficult to see. Now, researchers have constructed a waterproof 'e-glove' that wirelessly transmits hand gestures made underwater to a computer that translates them into messages. The new technology could someday help divers communicate better with each other and with boat crews on the surface.

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Researchers have made a significant advancement toward understanding how the human genome is organized inside a single cell. This knowledge is crucial for analyzing how DNA structure influences gene expression and disease processes.

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Researchers unveiled BeatProfiler, a groundbreaking new tool -- a comprehensive software that automates the analysis of heart cell function from video data. It's the first system to integrate the analysis of different heart function indicators, such as contractility, calcium handling, and force output into one tool, speeding up the process significantly and reducing the chance for errors. BeatProfiler enabled the researchers to not only distinguish between different diseases and levels of their severity but also to rapidly and objectively test drugs that affect heart function.

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Researchers have discovered that a worm commonly used in the study of biology uses a set of proteins unlike those seen in other studied organisms to protect the ends of its DNA.

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Multidrug-resistant bacterial infections that cannot be treated by any known antibiotics pose a serious global threat. A research team has now introduced a method for the development of novel antibiotics to fight resistant pathogens. The drugs are based on protein building blocks with fluorous lipid chains.

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A new molecular test method helps to prove the authenticity of works of art. The new method could also help to make passwords secure against quantum computers.