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Categories: Biology: Molecular, Computer Science: General

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Researchers developed a foundational language model to decode mRNA sequences and optimize those sequences for vaccine development. The tool shows broader promise as a means for studying molecular biology.

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Biophysicists have demonstrated how heat flows through rock fissures could have created the conditions for the emergence of life.

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In a bid to restore privacy, researchers have created a new approach to designing cameras that process and scramble visual information before it is digitized so that it becomes obscured to the point of anonymity.

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Researchers have discovered how certain proteins can attach to special structures in RNA, called G-quadruplexes. Additionally, they have developed computational tools capable of predicting these protein-RNA interactions. The newfound ability to predict these interactions can help future work in understanding molecular pathways in the cell and pave the way for developing drugs targeting these RNA G-quadruplex binding proteins, that are found to be involved in disease such as cancer.

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A new study finds that UCYN-A, a species of nitrogen-fixing cyanobacteria, may be evolving organelle-like characteristics.

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The development of AI models is an overlooked climate culprit. Computer scientists have created a recipe book for designing AI models that use much less energy without compromising performance. They argue that a model's energy consumption and carbon footprint should be a fixed criterion when designing and training AI models.

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A recent breakthrough sheds light on how the malaria parasite, Plasmodium falciparum, invades human red blood cells. The study reveals the role of a sugar called sialic acid in this invasion process. The findings have major implications for malaria vaccine and drug development.

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A genomic study of human and selected nonhuman primate centromeres has revealed their unimaginable diversity and speed of evolutionary change. Although centromeres are vital to proper cell replication by assuring faithful transmision of genetic materials when cells divide, the complexity of their genomic organization had been almost impossible to study. The lack of centromere sequences hindered exploration of how these regions help maintain genetic integrity. Now, advanced technologies have shown scientists how greatly centromeres differ in size and structure.

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Researchers have taken a big step towards securing information against hacking. They have succeeded in using quantum encryption to securely transfer information 100 kilometers via fiber optic cable -- roughly equivalent to the distance between Oxford and London.

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Using a blink-and-you'll-miss-it experiment, researchers have discovered that individuals differ widely in the rate at which they perceive visual signals. Some people perceive a rapidly changing visual cue at frequencies that others cannot, which means some access more visual information per timeframe than others. This discovery suggests some people have an innate advantage in certain settings where response time is crucial, such as in ball sports, or in competitive gaming.

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Researchers have identified how the tick-borne Crimean-Congo haemorrhagic fever virus enters our cells. The results are an important step in the development of drugs against the deadly disease.

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Barley is one of the most important cereal crops on a global scale. Many barley cultivars produce a toxic alkaloid called gramine that affects the suitability of barley as fodder, but also helps to protect barley from pathogens. So far, the potential of manipulating gramine levels has not been harnessed for plant breeding, because the genetic basis of gramine production has been unresolved. Research groups now disclose the complete biosynthetic pathway of gramine and demonstrate how gramine biosynthesis can be introduced into model organisms or removed from barley.

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Biologists have uncovered a quality control timing mechanism tied to cell division. The 'stopwatch' function keeps track of mitosis and acts as a protective measure when the process takes too long, preventing the formation of cancerous cells.

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Branching patterns are prevalent in our natural environment and the human body, such as in the lungs and kidneys. For example, specific genes that express growth factor proteins are known to influence the development of the lungs' complex branches. Researchers have unveiled a regulatory system linking signal, force, and shape in mouse lung structure development. The team recognized that the signal protein ERK plays an active role in causing growing lung tissue to curve.

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A research team has addressed the long-standing challenge of creating artificial olfactory sensors with arrays of diverse high-performance gas sensors. Their newly developed biomimetic olfactory chips (BOC) are able to integrate nanotube sensor arrays on nanoporous substrates with up to 10,000 individually addressable gas sensors per chip, a configuration that is similar to how olfaction works for humans and other animals.

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New multidisciplinary research could lead to more efficient televisions, computer screens and lighting.

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Umwelt is a new a system that enables blind and low-vision users to author accessible, interactive charts representing data in three modalities: visualization, textual description, and sonification.

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Understanding the structure of proteins is critical for demystifying their functions and developing drugs that target them. To that end, a team of researchers has developed a way of using machine learning to rapidly predict multiple protein configurations to advance understanding of protein dynamics and functions.

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Tardigrade proteins are potential candidates in technologies centered on slowing the aging process and in long-term storage of human cells.

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Scientists have uncovered a unique mechanism that regulates the opening of stomata in plants. Phosphorylation of the amino acid Thr881 on the plasma membrane proton pump plays a key role in this process. The study paves the way for the targeted manipulation of plant physiology, with potential applications in agriculture and environmental sustainability.