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Categories: Biology: Molecular, Computer Science: General
Published Researchers develop solid-state thermal transistor for better heat management



A team of researchers has unveiled a first-of-its-kind stable and fully solid-state thermal transistor that uses an electric field to control a semiconductor device's heat movement. The group's study details how the device works and its potential applications. With top speed and performance, the transistor could open new frontiers in heat management of computer chips through an atomic-level design and molecular engineering. The advance could also further the understanding of how heat is regulated in the human body.
Published Female sex determining gene identified in mice



Researchers have identified a gene which is an early determining factor of ovary development in mice.
Published A known environmental hazard can change the epigenetics of cells



An international team of researchers has discovered that formaldehyde, a widely spread pollutant and common metabolite in our body, interferes in the epigenetic programming of the cell. This finding expands the knowledge of formaldehyde, previously considered only as a DNA mutagen, and helps establishing a further link with cancer.
Published Research connecting gut bacteria and oxytocin provides a new mechanism for microbiome-promoted health benefits



Researchers found that the hormone oxytocin, known to be involved in regulating feeding and social behavior and until now to be produced mostly in the brain, is also produced in the human intestine. Furthermore, gut resident bacteria L. reuteri can affect the production of gut-made oxytocin, providing the first insights into a mechanism by which these bacteria can influence human health.
Published Immunology: Dysfunction of mitochondria drives the exhaustion of T cells



In the immune system's fight against cancer and infections, the T cells often lose their power. Now immunologists may have found a possible explanation for this phenomenon.
Published Learning to forget -- a weapon in the arsenal against harmful AI



With the AI summit well underway, researchers are keen to raise the very real problem associated with the technology -- teaching it how to forget.
Published AI should be better understood and managed -- new research warns



Artificial Intelligence (AI) and algorithms can and are being used to radicalize, polarize, and spread racism and political instability, says an academic. An expert argues that AI and algorithms are not just tools deployed by national security agencies to prevent malicious activity online, but can be contributors to polarization, radicalism and political violence -- posing a threat to national security.
Published New study sheds light on the molecular mechanisms underlying lipid recycling within cells



Our understanding of how cells recycle lipids through autophagy -- a form of cellular degradation -- has grown significantly, thanks to a recent study. Using yeast as a model organism, the researchers explored the molecular mechanisms leading to the degradation of the phospholipid bilayers making up the cell membranes. Their findings improve our understanding of cellular degradation processes and related metabolic disorders.
Published First mice engineered to survive COVID-19 like young, healthy humans



Researchers have genetically engineered the first mice that get a human-like form of COVID-19, according to a new study.
Published New twist on optical tweezers



Optical tweezers use laser light to manipulate small particles. A new method has been advanced using Stampede2 supercomputer simulations that makes optical tweezers safer to use for potential biological applications, such as cancer therapy.
Published Plastic-eating bacteria turn waste into useful starting materials for other products



Mountains of used plastic bottles get thrown away every day, but microbes could potentially tackle this problem. Now, researchers report that they've developed a plastic-eating E. coli that can efficiently turn polyethylene terephthalate (PET) waste into adipic acid, which is used to make nylon materials, drugs and fragrances.
Published New techniques efficiently accelerate sparse tensors for massive AI models



New computational techniques, 'HighLight' and 'Tailors and Swiftiles,' could dramatically boost the speed and performance of high-performance computing applications like graph analytics or generative AI. The work, from MIT and NIVIDIA, aims to accelerate sparse tensors for AI models by introducing more efficient and flexible ways to take advantage of sparsity.
Published Late not great -- imperfect timekeeping places significant limit on quantum computers



Quantum physicists show that imperfect timekeeping places a fundamental limit to quantum computers and their applications. The team claims that even tiny timing errors add up to place a significant impact on any large-scale algorithm, posing another problem that must eventually be solved if quantum computers are to fulfill the lofty aspirations that society has for them.
Published Accelerating AI tasks while preserving data security



SecureLoop is a new search engine that can identify an optimal design for a deep neural network accelerator that preserves data security while improving energy efficiency and boosting performance. This could enable device manufacturers to increase the speed of demanding AI applications, while ensuring sensitive data remain safe from attackers.
Published Scientists create special 'telomouse' with human-like telomeres



Researchers introduce the 'Telomouse'. By making a subtle genetic alteration in standard lab mice, they've made the mouse telomeres, which protect the chromosome ends, more closely resemble those in humans. The Telomouse model, developed by incorporating a genetic variation from a mouse species with naturally shorter telomeres, provides a valuable resource for in-depth aging and cancer research. This discovery promises to reveal new insights into the genetics of aging and may contribute to enhanced longevity and well-being.
Published Intestinal bacteria metabolite promotes capture of antigens by dendritic cells



Dendritic cells are immune cells that capture and present antigens to T cells, activating an immune response. Researchers have discovered that short-chain fatty acids produced by intestinal bacteria regulate a crucial step in this process, the extension of dendritic 'arms.' This breakthrough finding could potentially lead to the development of disease prevention strategies involving beneficial bacteria and new drugs targeting the regulation of dendritic cell function.
Published Controlling organoids with light



Organoids help researchers understand biological processes in health and in disease. It is, however, difficult to influence the way in which they organize themselves into complex tissues. Now a group has found a new way to do so.
Published Novel device promotes efficient, real-time and secure wireless access



Researchers have created new technology for more accessible, real-time wireless connectivity.
Published Protein root discovery seals future of climate-proof plants



Researchers have discovered a protein that seals plant roots to regulate the uptake of nutrients and water from the soil, the discovery could help develop climate proof crops that require less water and chemical fertilizers.
Published Researchers solve protein mystery



Researchers have uncovered that proteins use a common chemical label as a shield to protect them from degradation, which in turn affects motility and aging.