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Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Where did the first sugars come from?      (via sciencedaily.com)     Original source 

Origin-of-life chemists propose that glyoxylate could have been the original source of sugars on the 'prebiotic' Earth

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: Evolutionary Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Biologists determine the evolutionary age of individual cell types providing critical insights for animal development      (via sciencedaily.com)     Original source 

A research team has recently made a significant discovery about the evolutionary age of different type of cells in a small animal called Caenorhabditis elegans (C. elegans). By using single-cell transcriptomic data and refined phylostratigraphy, the team determines the transcriptomic age of individual cells, which means they are able to estimate the evolutionary origin of different cells based on the age of the genes expressed in the cells.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Evolutionary Biology: General Biology: Microbiology Biology: Molecular
Published

Study compares de novo proteins with randomly produced proteins      (via sciencedaily.com)     Original source 

In a series of experiments, a team of researchers have compared de novo proteins with random-sequence proteins, looking at their stability and solubility. The results are set to advance basic research in this new field.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: Genetics Biology: Molecular
Published

Oral barrier is similar in ceramide composition to skin barrier      (via sciencedaily.com)     Original source 

Acylceramides and protein-bound ceramides are vital for the formation of the oral barrier in mice, similar to their role in skin, protecting from infection.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Genes are read faster and more sloppily in old age      (via sciencedaily.com)     Original source 

Scientists have demonstrated the following findings which apply across the animal kingdom: with increasing age, the transcriptional elongation speed of genes increases, whereby the quality of the gene products suffers. With dietary restrictions, these processes could be reversed.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Biology: Zoology
Published

Here's how a worm's embryonic cells changed its development potential      (via sciencedaily.com)     Original source 

Researchers have spotted how specific proteins within the chromosomes of roundworms enable their offspring to produce specialized cells generations later, a startling finding that upends classical thinking that hereditary information for cell differentiation is mostly ingrained within DNA and other genetic factors.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Researchers clear the way for well-rounded view of cellular defects      (via sciencedaily.com)     Original source 

New research investigates how cells divide, particularly in the fibrous environment of living tissue. Cells are typically studied in a flat environment, and the difference between flat and fibrous landscapes opens new windows into the behavior of cells and the diseases that impact them.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Broccoli consumption protects gut lining, reduces disease, in mice      (via sciencedaily.com)     Original source 

Broccoli is known to be beneficial to our health. For example, research has shown that increased consumption of the cruciferous vegetable decreases incidence of cancer and type 2 diabetes. In a recent study, researchers found that broccoli contains certain molecules that bind to a receptor within mice and help to protect the lining of the small intestine, thereby inhibiting the development of disease. The findings lend support to the idea that broccoli truly is a 'superfood.'

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Evolutionary Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Blind dating in bacteria evolution      (via sciencedaily.com)     Original source 

A team of researchers reconstructed long-extinct proteins of a UV protection system of cyanobacteria. The surprising result: the proteins were already compatible with each other when they first met. This discovery expands the knowledge horizon on the rules of evolution.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Offbeat: General Offbeat: Plants and Animals
Published

Researchers create embryo-like structures from monkey embryonic stem cells      (via sciencedaily.com)     Original source 

Human embryo development and early organ formation remain largely unexplored due to ethical issues surrounding the use of embryos for research as well as limited availability of materials to study. Investigators now report on the creation of embryo-like structures from monkey embryonic stem cells. The investigators also transferred these embryo-like structures into the uteruses of female monkeys and determined that the structures were able to implant and elicit a hormonal response similar to pregnancy.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Molecular
Published

Activating adult-born neurons through deep brain stimulation alleviates Alzheimer's symptoms in rodent models      (via sciencedaily.com)     Original source 

People with Alzheimer's disease develop defects in cognitive functions like memory as well as problems with noncognitive functions that can lead to anxiety and depression. Investigators used mice to study a process through which new neurons are generated in adulthood, called adult hippocampus neurogenesis (AHN). The research showed that deep brain stimulation of new neurons helped restore both cognitive and noncognitive functions in mouse models of Alzheimer's disease.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Complex assembly process involved in DNA virus replication      (via sciencedaily.com)     Original source 

In a twist on the question, 'Which came first, the chicken or the egg?', scientists have long faced a similar question about how human adenovirus replicates: 'Which comes first, assembly of the viral particle, or packaging of the viral genome?' Now, in a new study, scientists have answered that question, showing that viral proteins use a process called phase separation to coordinate production of viral progeny.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular Offbeat: General Offbeat: Paleontology and Archeology Offbeat: Plants and Animals Offbeat: Space Space: Astrophysics Space: General Space: The Solar System
Published

How were amino acids, one of the key building blocks of life, formed before the origin of life on Earth?      (via sciencedaily.com)     Original source 

The amino acid abundances of two Ryugu particles were measured and compared with their rocky components. The results demonstrate the important role that water plays in the formation of amino acids on the giant precursors of asteroids like Ryugu. Our solar system formed from a molecular cloud, which was composed of gas and dust that was emitted into the interstellar medium (ISM), a vast space between stars. On collapse of the molecular cloud, the early sun was formed, with a large disk of gas and dust orbiting it. The dusty material collided to produce rocky material that would eventually grow in size to give large bodies called planetesimals.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Microbiology Biology: Molecular Biology: Zoology
Published

Lab-grown fat could give cultured meat real flavor and texture      (via sciencedaily.com)     Original source 

Researchers have successfully bulk-produced fat tissue in the lab that has a similar texture and make-up to naturally occurring fats from animals.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Chemistry: Biochemistry Offbeat: General Offbeat: Plants and Animals
Published

A miniature heart in a petri dish: Organoid emulates development of the human heart      (via sciencedaily.com)     Original source 

A team has induced stem cells to emulate the development of the human heart. The result is a sort of 'mini-heart' known as an organoid. It will permit the study of the earliest development phase of our heart and facilitate research on diseases.

Computer Science: Artificial Intelligence (AI) Computer Science: Encryption Engineering: Robotics Research
Published

New cyber software can verify how much knowledge AI really knows      (via sciencedaily.com)     Original source 

With a growing interest in generative artificial intelligence (AI) systems worldwide, researchers have created software that is able to verify how much information an AI farmed from an organization's digital database.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Study to decode microbe-gut signaling suggests potential new treatment for IBD      (via sciencedaily.com)     Original source 

Fresh insights into how our bodies interact with the microbes living in our guts suggest that a two-drug combination may offer a new way to treat inflammatory bowel diseases such as Crohn's disease and ulcerative colitis.

Biology: Biochemistry Biology: Biotechnology Biology: Botany Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular Ecology: Endangered Species
Published

DELLA proteins could hold key to the next Green Revolution      (via sciencedaily.com)     Original source 

A family of 'promiscuous' proteins found in all land plants is responsible for many different plant functions, despite remaining relatively unchanged for over 450 million years.