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Categories: Biology: Molecular, Computer Science: Artificial Intelligence (AI)
Published Creativity in the age of generative AI: A new era of creative partnerships



Generative AI (e.g., ChatGPT) has propelled AI into the mainstream, raising concerns about job displacement and creative work. Experts now emphasize a need to focus on 'co-creativity,' the human-AI interaction instead. Extensive research is needed for comprehending co-creativity which is crucial for the future development of AI.
Published AI system self-organizes to develop features of brains of complex organisms



Scientists have shown that placing physical constraints on an artificially-intelligent system -- in much the same way that the human brain has to develop and operate within physical and biological constraints -- allows it to develop features of the brains of complex organisms in order to solve tasks.
Published AI: Researchers develop automatic text recognition for ancient cuneiform tablets



A new artificial intelligence (AI) software is now able to decipher difficult-to-read texts on cuneiform tablets. Instead of photos, the AI system uses 3D models of the tablets, delivering significantly more reliable results than previous methods. This makes it possible to search through the contents of multiple tablets to compare them with each other. It also paves the way for entirely new research questions.
Published Heart repair via neuroimmune crosstalk



Unlike humans, zebrafish can completely regenerate their hearts after injury. They owe this ability to the interaction between their nervous and immune systems, as researchers now report.
Published New method to help with analysis of single cell data



CITE-seq (cellular indexing of transcriptomes and epitopes) is an RNA sequencing-based method that simultaneously quantifies cell surface protein and transcriptomic data within a single cell readout. The ability to study cells concurrently offers unprecedented insights into new cell types, disease states or other conditions. While CITE-seq solves the problem of detecting a limited number of proteins while using single-cell sequencing in an unbiased way, one of its limitations is the high levels of background noise that can hinder analysis.
Published Genomic tug of war could boost cancer therapy



Researchers have discovered a 'genomic tug of war' in animal studies that could influence how well certain patients -- or certain cancers -- respond to decitabine, a drug used to treat myelodysplastic syndromes that is plagued by drug resistance issues. For the first time, researchers show that decitabine causes coding and non-coding regions of DNA to engage in a tug of war for a gene activator, called H2A.Z. Typically, deticabine draws this gene activator away from coding DNA, causing gene expression to grind to a halt and cells to die. However, many types of cancer have very high levels of H2A.Z, which may help them overcome this decitabine-induced tug of war, allowing the cancer to grow.
Published How cell identity is preserved when cells divide



A new theoretical model helps explain how epigenetic memories, encoded in chemical modifications of chromatin, are passed from generation to generation. Within each cell's nucleus, researchers suggest, the 3D folding patterns of its genome determines which parts of the genome will be marked by these chemical modifications.
Published Much more than waste: Tiny vesicles exchange genetic information between cells in the sea



Researchers take a look at data that has so far been mostly discarded as contamination, revealing the previously underestimated role of extracellular vesicles (EVs). These are important for the exchange of genetic information between cells and thus for the microbial community in the sea.
Published The mind's eye of a neural network system



A new tool, based on topology, makes finding the areas where neural networks are confused as simple as spotting mountaintops from an airplane. The ability to spot and address those areas of confusion should enable more confident application of neural networks in high-stakes decision scenarios or image prediction tasks like healthcare and research.
Published Hormones have the potential to treat liver fibrosis



Researchers have discovered previously unknown changes in a specific type of liver cells, potentially opening avenues for a new treatment for liver fibrosis, a potentially life-threatening condition. Currently, there are no drugs available to treat liver fibrosis.
Published Realistic talking faces created from only an audio clip and a person's photo



A team of researchers has developed a computer program that creates realistic videos that reflect the facial expressions and head movements of the person speaking, only requiring an audio clip and a face photo. DIverse yet Realistic Facial Animations, or DIRFA, is an artificial intelligence-based program that takes audio and a photo and produces a 3D video showing the person demonstrating realistic and consistent facial animations synchronised with the spoken audio (see videos).
Published Use it or lose it: New robotic system assesses mobility after stroke



Stroke is a leading cause of long-term disability worldwide. Each year more than 15 million people worldwide have strokes, and three-quarters of stroke survivors will experience impairment, weakness and paralysis in their arms and hands. Many stroke survivors rely on their stronger arm to complete daily tasks, from carrying groceries to combing their hair, even when the weaker arm has the potential to improve.
Published How bacteria recognize viral invasion and activate immune defenses



Bacteria have an array of strategies to counter viral invasion, but how they first spot a stranger in their midst has long been a mystery.
Published Colliding ribosomes activate RNA repair



Researchers discover how ribosomes contribute to the recognition and removal of RNA crosslinking damage.
Published Novel C. diff structures are required for infection, offer new therapeutic targets



Newly discovered iron storage 'ferrosomes' inside the bacterium C. diff -- the leading cause of hospital-acquired infections -- are important for infection in an animal model and could offer new targets for antibacterial drugs. They also represent a rare demonstration of a membrane-bound structure inside a pathogenic bacterium, upsetting the biological dogma that bacteria do not contain organelles.
Published This 3D printer can watch itself fabricate objects



Engineers have developed a high-throughput, multimaterial 3D inkjet printer that uses computer vision to rapidly and automatically control the amount of material being deposited during the printing process in real time. This enables the use of a wide range of materials for fabrication.
Published Individual back training machine developed



18 percent of reported sick leave relates to musculoskeletal ailments, in particular back-related disorders. The GyroTrainer is an intelligent training device that resembles a balance board. It uses artificial intelligence to adjust the difficulty level to the individual patient's current ability.
Published A tale of two proteins: Fundamental research could make growing better crops like clockwork



Rhomboid-like protein 10, or RBL10, is thought to be an enzyme that degrades other proteins in the chloroplast membrane, but its function is largely unknown. Researchers are studying how RBL10 affects photosynthetic membrane lipid metabolism, an essential process in photosynthesis.
Published New discovery on how green algae count cell divisions illuminates key step needed for the evolution of multicellular life



An international research team has made an unexpected discovery of a biased counting mechanism used by the single-celled green alga Chlamydomonas to control cell division.
Published How marine bristle worms use a special protein to distinguish between sunlight and moonlight



A research team has presented its findings on the functioning of an atypical cryptochrome protein (Cry). These proteins are found in a variety of organisms, and they are often involved in light-controlled biological processes. The marine bristle worm Platynereis dumerilii, for example, employs a special Cry protein designated L-Cry to distinguish between sunlight and moonlight as well as between different moon phases. This is essential for the worms to synchronize their reproduction to the full moon phase via an inner monthly calendar, also called circalunar clock.