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Categories: Biology: Molecular, Computer Science: Quantum Computers
Published How cells are ahead of the curve
(via sciencedaily.com) Original source The curvature of a surface determines the migration behavior of biological cells. They preferentially move along valleys or grooves while avoiding ridges. These findings gave rise to a model predicting cellular behavior. Such universal principles now allow a better understanding of the migration of immune and cancer cells, paving the way for new treatment options.
Published Engineers measure pH in cell condensates
(via sciencedaily.com) Original source In a first for the condensate field, researchers have figured out how nucleolar sub-structures are assembled. This organization gives rise to unique pH profiles within nucleoli, which they measured and compared with the pH of nearby non-nucleolar condensates including nuclear speckles and Cajal bodies.
Published Machine learning classifier accelerates the development of cellular immunotherapies
(via sciencedaily.com) Original source Making a personalized T cell therapy for cancer patients currently takes at least six months. Scientists have shown that the laborious first step of identifying tumor-reactive T cell receptors for patients can be replaced with a machine learning classifier that halves this time.
Published Small amounts of licorice raise blood pressure, study finds
(via sciencedaily.com) Original source It is known that large amounts of licorice cause high blood pressure. A new study now shows that even small amounts of licorice raise blood pressure. The individuals who react most strongly also show signs of strain on the heart.
Published Alzheimer's drug fermented with help from AI and bacteria moves closer to reality
(via sciencedaily.com) Original source Researchers combined artificial intelligence and chemical biosensors to ferment the precursor of an Alzheimer's drug in bacteria.
Published New bioengineered protein design shows promise in fighting COVID-19
(via sciencedaily.com) Original source A recent scientific breakthrough has emerged from the work of researchers aiming to combat SARS-CoV-2, the virus responsible for COVID-19. The study focuses on the design and development of a novel protein capable of binding to the spike proteins found on the surface of the coronavirus. The goal behind this innovative approach is twofold: first, to identify and recognize the virus for diagnostic purposes, and second, to hinder its ability to infect human cells.
Published Sleep-wake rhythm: Fish change our understanding of sleep regulation
(via sciencedaily.com) Original source Researchers have discovered that some fish -- unlike humans -- do not need orexin to stay awake. This molecule was thought to be necessary for normal wake and sleep rhythms in vertebrates. Humans without orexin suffer from narcolepsy.
Published New discovery reveals how the egg controls sperm entry
(via sciencedaily.com) Original source After the egg has been fertilized by a sperm, the surrounding egg coat tightens, mechanically preventing the entry of additional sperm and the ensuing death of the embryo, a new study finds. The work also explains how mutations in egg coat proteins can cause female infertility and may eventually lead to new contraceptive methods.
Published Even cells know the importance of recycling
(via sciencedaily.com) Original source Researchers uncovered the mechanistic details behind how several proteins interact to help cells recognize and remove damaged mitochondria. Optineurin (OPTN) and its interactions are needed to provide a contact site for another protein, Tank-binding kinase 1 (TBK1), during this process. The OPTN-TBK1 relationship is necessary for these mitochondria to be recognized and eliminated from the cell. This mechanism may have relevance for developing drugs to treat Parkinson's disease.
Published Sulfur and the origin of life
(via sciencedaily.com) Original source A new study shines a spotlight on sulfur, a chemical element that, while all familiar, has proved surprisingly resistant to scientific efforts in probing its role in the origin of life.
Published Tryptophan in diet, gut bacteria protect against E. coli infection
(via sciencedaily.com) Original source Gut bacteria and a diet rich in the amino acid tryptophan can play a protective role against pathogenic E. coli, which can cause severe stomach upset, cramps, fever, intestinal bleeding and renal failure.
Published New computational strategy boosts the ability of drug designers to target proteins inside the membrane
(via sciencedaily.com) Original source Hitting targets embedded within the cell membrane has long been difficult for drug developers due to the membrane's challenging biochemical properties. Now, chemists have demonstrated new custom-designed proteins that can efficiently reach these 'intramembrane' targets.
Published Staying in the loop: How superconductors are helping computers 'remember'
(via sciencedaily.com) Original source To advance neuromorphic computing, some researchers are looking at analog improvements -- advancing not just software, but hardware too. Research shows a promising new way to store and transmit information using disordered superconducting loops.
Published Satellites for quantum communications
(via sciencedaily.com) Original source Through steady advances in the development of quantum computers and their ever-improving performance, it will be possible in the future to crack our current encryption processes. To address this challenge, researchers are developing encryption methods that will apply physical laws to prevent the interception of messages. To safeguard communications over long distances, the QUICK space mission will deploy satellites.
Published Milk to the rescue for diabetics? Cow produces human insulin in milk
(via sciencedaily.com) Original source An unassuming brown bovine from the south of Brazil has made history as the first transgenic cow capable of producing human insulin in her milk. The advancement could herald a new era in insulin production, one day eliminating drug scarcity and high costs for people living with diabetes.
Published A simple and robust experimental process for protein engineering
(via sciencedaily.com) Original source A protein engineering method using simple, cost-effective experiments and machine learning models can predict which proteins will be effective for a given purpose, according to a new study.
Published Scientists find weak points on Epstein-Barr virus
(via sciencedaily.com) Original source Studies of interactions between two lab-generated monoclonal antibodies (mAbs) and an essential Epstein-Barr virus (EBV) protein have uncovered targets that could be exploited in designing treatments and vaccines for this extremely common virus.
Published How a natural compound from sea squirts combats cancer
(via sciencedaily.com) Original source Trabectedin, a promising drug derived from the sea squirt Ecteinascidia turbinata, has shown potential in combating cancers resistant to conventional treatments. However, its precise mechanism of action has remained elusive -- until now.
Published Powerful new tool ushers in new era of quantum materials research
(via sciencedaily.com) Original source Research in quantum materials is paving the way for groundbreaking discoveries and is poised to drive technological advancements that will redefine the landscapes of industries like mining, energy, transportation, and medtech. A technique called time- and angle-resolved photoemission spectroscopy (TR-ARPES) has emerged as a powerful tool, allowing researchers to explore the equilibrium and dynamical properties of quantum materials via light-matter interaction.
Published Design rules and synthesis of quantum memory candidates
(via sciencedaily.com) Original source In the quest to develop quantum computers and networks, there are many components that are fundamentally different than those used today. Like a modern computer, each of these components has different constraints. However, it is currently unclear what materials can be used to construct those components for the transmission and storage of quantum information.