Showing 20 articles starting at article 281

< Previous 20 articles        Next 20 articles >

Categories: Biology: Molecular, Mathematics: Puzzles

Return to the site home page

     (via sciencedaily.com)     Original source 

Trabectedin, a promising drug derived from the sea squirt Ecteinascidia turbinata, has shown potential in combating cancers resistant to conventional treatments. However, its precise mechanism of action has remained elusive -- until now.

     (via sciencedaily.com)     Original source 

Researchers have identified the protein that enables mammals to sense cold, filling a long-standing knowledge gap in the field of sensory biology.

     (via sciencedaily.com)     Original source 

New research describes the science behind a promising technique to treat infertility by turning a skin cell into an egg that is capable of producing viable embryos. The technique could be used by women of advanced maternal age or for those who are unable to produce viable eggs due to previous treatment for cancer or other causes. It also raises the possibility of men in same-sex relationships having children who are genetically related to both parents.

     (via sciencedaily.com)     Original source 

Researchers have discovered a mechanism steering the evolution of multicellular life. They identified how altered protein folding drives multicellular evolution.

     (via sciencedaily.com)     Original source 

A team deciphers complicated mechanism underlying genetic diversity.

     (via sciencedaily.com)     Original source 

For the first time, scientists have developed artificial nucleotides, the building blocks of DNA, with several additional properties in the laboratory.

     (via sciencedaily.com)     Original source 

Retinoic acid, the active state of Vitamin A, appears to regulate how stem cells enter and exit a transient state central to their role in wound repair.

     (via sciencedaily.com)     Original source 

All modern Plasmodium falciparum, the deadliest malaria parasite in humans, are descendants of one initial infection and so are very closely related, with relatively limited genetic differences. A long-standing mystery in the field has revolved around a very few locations in the P. falciparum genome where there are 'spikes' of mutations -- far more than anywhere else. Researchers have identified two genes in which these unusual mutation spikes result from DNA being copied and pasted from one gene to another.

     (via sciencedaily.com)     Original source 

A research team has recently made a significant breakthrough in understanding how the DNA copying machine helps pass on epigenetic information to maintain gene traits at each cell division. Understanding how this coupled mechanism could lead to new treatments for cancer and other epigenetic diseases by targeting specific changes in gene activity.

     (via sciencedaily.com)     Original source 

Entropy is often associated with disorder and chaos, but in biology it is related to energy efficiency and is closely linked to metabolism, the set of chemical reactions that sustain life. An international research team has now developed a novel methodology for the measurement of entropy production at the scale of a nanometer, meaning one-billionth of a meter. The new approach enabled the scientists to measure the heat flow, known as the entropy production rate, of single red blood cells.

     (via sciencedaily.com)     Original source 

An updated method for directly observing physical interactions between cells, could allow scientists to one day map every possible cell interaction.

     (via sciencedaily.com)     Original source 

'Random DNA' is naturally active in the one-celled fungi yeast, while such DNA is turned off as its natural state in mammalian cells, despite their having a common ancestor a billion years ago and the same basic molecular machinery, a new study finds.

     (via sciencedaily.com)     Original source 

Epigenetic changes play important roles in cancer, metabolic and aging-related diseases, but also during loss of resilience as they cause the genetic material to be incorrectly interpreted in affected cells. A major study now provides important new insights into how complex epigenetic modification signatures regulate the genome. This study will pave the way for new treatments of diseases caused by faulty epigenetic machineries.

     (via sciencedaily.com)     Original source 

Researchers shed light on archaea, intriguing microbes found in extreme environments but also in the human gut microbiome.

     (via sciencedaily.com)     Original source 

A globally distributed single-celled organism that occurs in harmful algal blooms has been found to exhibit an unusual organisation of photosynthesis. Researchers have taken a closer look at the unusual cell biology of the species Prorocentrum cordatum from the group of dinoflagellates. The results of their study could help to better understand the role of the species in the environment and the increased occurrence of algal blooms at higher water temperatures.

     (via sciencedaily.com)     Original source 

Scientists provide fresh insights on the origins of life, presenting compelling evidence supporting the 'RNA World' hypothesis. The study unveils an RNA enzyme that can make accurate copies of other functional RNA strands, while also allowing new variants of the molecule to emerge over time. These remarkable capabilities suggest the earliest forms of evolution may have occurred on a molecular scale in RNA, and also bring scientists one step closer to re-creating autonomous RNA-based life in the laboratory.

     (via sciencedaily.com)     Original source 

Secrets of photosynthesis have been discovered at atomic level, shedding important new light on this plant super-power that greened the earth more than a billion years ago.

     (via sciencedaily.com)     Original source 

Researchers identified the proteins of a CO2-fixing organelle, namely, 'pyrenoid,' in the marine algal group Chlorarachniophyta and revealed various pyrenoid-associated proteins among algal groups, suggesting the independent evolution of pyrenoids in different algal groups.

     (via sciencedaily.com)     Original source 

Researchers succeed at generating 3D visualizations of chloroplasts' copying machines.

     (via sciencedaily.com)     Original source 

Researchers have discovered a key mechanism used by Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV8), to induce cancer. The research points to effective new treatment options for KSHV-associated cancers, including Kaposi's sarcoma, primary effusion lymphoma, and HHV8-associated multicentric Castleman disease.