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Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Molecular
Published

New system triggers cellular waste disposal      (via sciencedaily.com)     Original source 

Established treatments for cancer and other diseases often focus on inhibiting harmful enzymes to mitigate their effects. However, a more innovative approach has emerged: harnessing the cell's natural waste disposal system not just to deactivate but to entirely eradicate these proteins. Researchers have previously demonstrated the efficacy of this approach through two distinct methods. Now they unveil a third system capable of targeting and disposing of previously inaccessible proteins.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Bridging diet, microbes, and metabolism: Implications for metabolic disorders      (via sciencedaily.com)     Original source 

Mounting evidence suggests that the secret to understanding human health and combating metabolic diseases lies hidden within the microscopic world of our gut bacteria. Recent research reveals that a specific fatty acid produced by gut bacteria directly influences fat metabolism in animals. This research is pivotal as it sheds light on the complex interplay between the diet, gut microbiota, and host metabolic health, offering insights that could open new avenues in our approach to managing metabolic disorders.

Biology: Biochemistry Biology: Botany Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Environmental: General Environmental: Water Geoscience: Environmental Issues Geoscience: Geochemistry
Published

Photosynthetic mechanism of purple sulfur bacterium adapted to low-calcium environments      (via sciencedaily.com)     Original source 

Purple sulfur bacteria (PSB) convert light energy into chemical energy through photosynthesis. Interestingly, certain species can photosynthesize even in environments with low-calcium levels. Using cryo-electron microscopy, researchers unveiled the structure of light-harvesting complexes and elucidated the mechanism that facilitates photosynthesis under low-calcium conditions.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Researchers are using RNA in a new approach to fight HIV      (via sciencedaily.com)     Original source 

A pharmacy associate professor has developed a novel nanomedicine loaded with genetic material called small interfering RNAs (siRNA) to fight human immunodeficiency virus (HIV) using gene therapy.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Biology: Zoology
Published

Eating too much protein is bad for your arteries, and this amino acid is to blame      (via sciencedaily.com)     Original source 

Consuming over 22% of dietary calories from protein can lead to increased activation of immune cells that play a role in atherosclerotic plaque formation and drive the disease risk, new study showed.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: Evolutionary Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Toxoplasmosis: Evolution of infection machinery      (via sciencedaily.com)     Original source 

Researchers have identified a protein that evolved concurrently with the emergence of cellular compartments crucial for the multiplication of the toxoplasmosis pathogen.

Biology: Biochemistry Biology: Biotechnology Biology: Botany Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Ecology: Endangered Species Geoscience: Geochemistry
Published

Asexual propagation of crop plants gets closer      (via sciencedaily.com)     Original source 

When the female gametes in plants become fertilized, a signal from the sperm activates cell division, leading to the formation of new plant seeds. This activation can also be deliberately triggered without fertilization, as researchers have shown. Their findings open up new avenues for the asexual propagation of crop plants.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: Evolutionary Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Biology: Zoology Offbeat: General Offbeat: Paleontology and Archeology Offbeat: Plants and Animals
Published

Ancient retroviruses played a key role in the evolution of vertebrate brains      (via sciencedaily.com)     Original source 

Researchers report that ancient viruses may be to thank for myelin -- and, by extension, our large, complex brains. The team found that a retrovirus-derived genetic element or 'retrotransposon' is essential for myelin production in mammals, amphibians, and fish. The gene sequence, which they dubbed 'RetroMyelin,' is likely a result of ancient viral infection, and comparisons of RetroMyelin in mammals, amphibians, and fish suggest that retroviral infection and genome-invasion events occurred separately in each of these groups.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Chemistry: Biochemistry
Published

Team creates novel rabies viral vectors for neural circuit mapping      (via sciencedaily.com)     Original source 

A research team has created 20 new recombinant rabies viral vectors for neural circuit mapping that offer a range of significant advantages over existing tools, including the ability to detect microstructural changes in models of aging and Alzheimer's disease brain neurons.

Biology: Biochemistry Biology: Biotechnology Biology: Botany Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Researchers uncover mechanisms behind enigmatic shapes of nuclei      (via sciencedaily.com)     Original source 

White blood cells known as neutrophils feature a nucleus that is structured strikingly different than most nuclei. These unique shapes permit neutrophils to travel all over the body to combat invading pathogens. Scientists have now deciphered the shapeshifting puzzle of the neutrophil nucleus.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Biology: Zoology Offbeat: Earth and Climate Offbeat: General Offbeat: Plants and Animals
Published

By growing animal cells in rice grains, scientists dish up hybrid food      (via sciencedaily.com)     Original source 

From lab-grown chicken to cricket-derived protein, these innovative alternatives offer hope for a planet struggling with the environmental and ethical impacts of industrial agriculture. Now, scientists add a new recipe to the list -- cultured beef rice -- by growing animal muscle and fat cells inside rice grains. The method results in a nutritious and flavorful hybrid food that, once commercialized, could offer a more affordable protein alternative with a smaller carbon footprint.

Biology: Biochemistry Biology: Botany Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular Ecology: Endangered Species Environmental: Water Geoscience: Earth Science Geoscience: Environmental Issues
Published

Controlling root growth direction could help save crops and mitigate climate change      (via sciencedaily.com)     Original source 

Scientists have determined how the well-known plant hormone ethylene is crucial in controlling the angle at which roots grow. The findings can be used to engineer plants and crops that withstand the environmental stresses of climate change and drought, and perhaps to create plants that remove carbon dioxide from the atmosphere and store it deep underground to help mitigate climate change.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Molecular
Published

Personalized adhesives for inner healing -- now tailored just for you      (via sciencedaily.com)     Original source 

Scientists develop novel underwater bio-adhesive patches with mussel adhesive protein.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Geoscience: Environmental Issues Geoscience: Geochemistry
Published

Low-cost microbe can speed biological discovery      (via sciencedaily.com)     Original source 

Researchers have created a new version of a microbe to compete economically with E. coli -- a bacteria commonly used as a research tool due to its ability to synthesize proteins -- to conduct low-cost and scalable synthetic biological experiments.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

New trial highlights incremental progress towards a cure for HIV-1      (via sciencedaily.com)     Original source 

A new clinical trial suggests that a combination of the drug vorinostat and immunotherapy can coax HIV-infected cells out of latency and attack them. The findings highlight how close -- yet still far -- researchers have come to developing a cure for HIV-1.

Biology: Developmental Biology: Molecular
Published

Why do flies fall in love? Researchers tease out the signals behind fruit fly courtship songs      (via sciencedaily.com)     Original source 

Researchers have pinpointed the group of neurons in the nerve cord -- a structure analogous to our spinal cord -- that produce and pattern the fly's two major courtship songs. They've also measured neuronal activity in these cells while flies were singing to understand how these neurons control each type of song.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Molecular
Published

Nutrients direct intestinal stem cell function and affect aging      (via sciencedaily.com)     Original source 

The capacity of intestinal stem cells to maintain cellular balance in the gut decreases upon aging. Researchers have discovered a new mechanism of action between the nutrient adaptation of intestinal stem cells and aging. The finding may make a difference when seeking ways to maintain the functional capacity of the aging gut.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Molecular
Published

New research uncovers biological drivers of heart disease risk      (via sciencedaily.com)     Original source 

Over the past 15 years, researchers have identified hundreds of regions in the human genome associated with heart attack risk. However, researchers lack efficient ways to explore how these genetic variants are molecularly connected to cardiovascular disease, limiting efforts to develop therapeutics. To streamline analysis of hundreds of genetic variants associated with coronary artery disease (CAD), a team of researchers combined multiple sequencing and experimental techniques to map the relationship between known CAD variants and the biological pathways they impact.