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Categories: Biology: Molecular, Mathematics: General
Published Father's diet before conception influences children's health
(via sciencedaily.com) Original source A recent study provides new insights into how fathers' diets and overweight can affect their children's health even before conception. The findings of the study can help develop preventive health measures for men wishing to become fathers: The healthier the father's diet, the lower the risk for their children to develop obesity or diseases such as diabetes later in life.
Published Exercising during pregnancy normalizes eating behaviors in offspring from obese mice
(via sciencedaily.com) Original source Maternal obesity impacts the eating behaviors of offspring via long-term overexpression of the microRNA miR-505-5p, according to a new study.
Published New model allows a computer to understand human emotions
(via sciencedaily.com) Original source Researchers have developed a model that enables computers to interpret and understand human emotions, utilizing principles of mathematical psychology. In the future, the model can help the computer to adapt its own behavior and guide an irritated or anxious user in different ways. The implications of such technology are profound, offering a glimpse into a future where computers are not merely tools, but empathetic partners in user interaction.
Published New open-source platform allows users to evaluate performance of AI-powered chatbots
(via sciencedaily.com) Original source Researchers have developed a platform for the interactive evaluation of AI-powered chatbots such as ChatGPT. A team of computer scientists, engineers, mathematicians and cognitive scientists developed an open-source evaluation platform called CheckMate, which allows human users to interact with and evaluate the performance of large language models (LLMs).
Published Unraveling the physics of knitting
(via sciencedaily.com) Original source A team used experiments and simulations to quantify and predict how knit fabric response can be programmed. By establishing a mathematical theory of knitted materials, the researchers hope that knitting -- and textiles in general -- can be incorporated into more engineering and manufacturing applications.
Published The embryo assembles itself
(via sciencedaily.com) Original source Biological processes depend on puzzle pieces coming together and interacting. Under specific conditions, these interactions can create something new without external input. This is called self-organization, as seen in a school of fish or a flock of birds. Interestingly, the mammalian embryo develops similarly. Scientists now introduce a mathematical framework that analyzes self-organization from a single cell to a multicellular organism.
Published Groundbreaking progress in quantum physics: How quantum field theories decay and fission
(via sciencedaily.com) Original source An international research team has sparked interest in the scientific community with results in quantum physics. In their current study, the researchers reinterpret the Higgs mechanism, which gives elementary particles mass and triggers phase transitions, using the concept of 'magnetic quivers.'
Published Paving the way for hydrogen from algae enzymes
(via sciencedaily.com) Original source Under certain conditions, some algae are able to produce hydrogen -- a much sought-after green energy source. Its production takes place in the unique catalytic center of the unicellular algae and is only possible if certain cofactors of the relevant proteins are present. Researchers have identified how such a cofactor, the so-called hydrogen cluster, is assembled. Specifically, they describe the previously unexplained role of the enzyme HydF, which is involved in the final steps of assembly.
Published AI-controlled stations can charge electric cars at a personal price
(via sciencedaily.com) Original source As more and more people drive electric cars, congestion and queues can occur when many people need to charge at the same time. A new study shows how AI-controlled charging stations, through smart algorithms, can offer electric vehicle users personalized prices, and thus minimize both price and waiting time for customers. But the researchers point to the importance of taking the ethical issues seriously, as there is a risk that the artificial intelligence exploits information from motorists.
Published The world's most powerful anti-fungal chemistries cause fungal pathogens to self-destruct
(via sciencedaily.com) Original source Scientists have discovered that the most widely-used class of antifungals in the world cause pathogens to self-destruct. The research could help improve ways to protect food security and human lives.
Published New, modified CRISPR protein can fit inside virus used for gene therapy
(via sciencedaily.com) Original source Researchers have developed a novel version of a key CRISPR gene-editing protein that shows efficient editing activity and is small enough to be packaged within a non-pathogenic virus that can deliver it to target cells.
Published Researchers apply quantum computing methods to protein structure prediction
(via sciencedaily.com) Original source Researchers recently published findings that could lay the groundwork for applying quantum computing methods to protein structure prediction.
Published hnRNPM, a guardian of the integrity of cellular protein production
(via sciencedaily.com) Original source Researchers have discovered that the protein hnRNPM prevents the cell from making mistakes while it is producing new proteins, which helps maintain the integrity of this vital process.
Published Editing without 'cutting': Molecular mechanisms of new gene-editing tool revealed
(via sciencedaily.com) Original source New research has determined the spatial structure of various processes of a novel gene-editing tool called 'prime editor.' Functional analysis based on these structures also revealed how a 'prime editor' could achieve reverse transcription, synthesizing DNA from RNA, without 'cutting' both strands of the double helix. Clarifying these molecular mechanisms contributes greatly to designing gene-editing tools accurate enough for gene therapy treatments.
Published Chicken feathers to deliver chemotherapy drugs and repair enzymes
(via sciencedaily.com) Original source A new method of drug delivery using proline, an amino acid found in chicken feathers and skin tissue, could be used to limit the side effects of chemotherapy and repair important enzymes, new research suggests.
Published Intermittent fasting shows promise in improving gut health, weight management
(via sciencedaily.com) Original source Participants following an intermittent fasting and protein-pacing regimen, which involves evenly spaced protein intake throughout the day, saw better gut health, weight loss and metabolic responses. These benefits were notably greater than those seen with simple calorie restriction. The findings could advance our understanding of the relationship between the gut microbiome and metabolism and improve strategies for managing obesity.
Published Mechanisms for selective multiple sclerosis treatment strategy
(via sciencedaily.com) Original source Researchers have demonstrated how B cells infected with the Epstein-Barr virus (EBV) can contribute to a pathogenic, inflammatory phenotype that contributes to multiple sclerosis (MS); the group has also shown how these problematic B cells can be selectively targeted in a way that reduces the damaging autoimmune response of multiple sclerosis.
Published 'Cloaked' proteins deliver cancer-killing therapeutics into cells
(via sciencedaily.com) Original source Scientists have designed a way to 'cloak' proteins in a generalized technique that could lead to repurposing things like antibodies for biological research and therapeutic applications.
Published Genetic mosaicism more common than thought
(via sciencedaily.com) Original source Researchers found that approximately one in 40 human bone marrow cells carry massive chromosomal alterations without causing any apparent disease or abnormality. Even so-called normal cells carry all sorts of genetic mutations, meaning there are more genetic differences between individual cells in our bodies than between different human beings. The discovery was enabled by a single-cell sequencing technology called Strand-seq, a unique DNA sequencing technique that can reveal subtle details of genomes in single cells that are too difficult to detect with other methods.
Published Observing mammalian cells with superfast soft X-rays
(via sciencedaily.com) Original source Researchers have developed a new technique to view living mammalian cells. The team used a powerful laser, called a soft X-ray free electron laser, to emit ultrafast pulses of illumination at the speed of femtoseconds, or quadrillionths of a second. With this they could capture images of carbon-based structures in living cells for the first time, before the soft X-ray radiation damaged them.