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Categories: Biology: Molecular, Mathematics: General
Published Increasing legumes and reducing red meat is safe for bone health and protein intake
(via sciencedaily.com) Original source A study has demonstrated that the partial substitution of red and processed meat with pea- and faba bean -- based food products ensured sufficient intake of amino acids in the diet and did not negatively affect bone metabolism.
Published Scientists reveal how sensory protein changes shape with nanometer resolution
(via sciencedaily.com) The sensory receptor PIEZO1 changes shape in response to mechanical stimuli. The super high-resolution microscopy technology used in this discovery is a breakthrough in enabling protein structures to be studied within the cellular environment.
Published Researchers use mathematical modeling and dynamic biomarkers to characterize metastatic disease during adaptive therapy
(via sciencedaily.com) Researchers demonstrate how mathematical modeling combined with dynamic biomarkers can be used to characterize metastatic disease and identify appropriate therapeutic approaches to improve patient outcomes.
Published Scientists uncover a surprising connection between number theory and evolutionary genetics
(via sciencedaily.com) An interdisciplinary team of mathematicians, engineers, physicists, and medical scientists has uncovered an unexpected link between pure mathematics and genetics, that reveals key insights into the structure of neutral mutations and the evolution of organisms.
Published Researcher turns one of the basic rules of construction upside down
(via sciencedaily.com) Original source Structural engineers are familiar with seventeenth-century scientist Robert Hooke's theory that a hanging chain will mirror the shape of an upstanding rigid arch. However, new research now shows that this common-held belief is incorrect because, regardless of the similarities, the hanging chain and the arch are two incompatible mechanical systems.
Published GPT detectors can be biased against non-native English writers
(via sciencedaily.com) Original source Researchers show that computer programs commonly used to determine if a text was written by artificial intelligence tend to falsely label articles written by non-native language speakers as AI-generated. The researchers caution against the use of such AI text detectors for their unreliability, which could have negative impacts on individuals including students and those applying for jobs.
Published Board games are boosting math ability in young children
(via sciencedaily.com) Board games based on numbers, like Monopoly, Othello and Chutes and Ladders, make young children better at math, according to a comprehensive review of research published on the topic over the last 23 years.
Published Number cruncher calculates whether whales are acting weirdly
(via sciencedaily.com) Original source We humans can be a scary acquaintance for whales in the wild. This includes marine biologists tagging them with measuring devices to understand them better. These experiences can make whales behave erratically for a while. Such behaviour can affect research quality and highlights an animal ethics dilemma. Now, researchers have figured out how to solve the problems with math.
Published Deciphering the thermodynamic arrow of time in large-scale complex networks
(via sciencedaily.com) A solution for temporal asymmetry -- or entropy production -- in thermodynamics has been developed to further our understanding of the behavior of biological systems, machine learning, and AI tools. The researchers worked on the time-irreversible Ising model dynamics caused by asymmetric connections between neurons.
Published Combining maths with music leads to higher scores, suggests review of 50 years of research
(via sciencedaily.com) Original source Children do better at maths when music is a key part of their lessons, an analysis of almost 50 years of research on the topic has revealed.
Published Evaluating cybersecurity methods
(via sciencedaily.com) Original source Researchers created a generic framework that enables an engineer or scientist to evaluate the effectiveness of defense schemes that seek to limit a hacker's ability to learn secret information by observing the behavior of a victim computer program.
Published What math can teach us about standing up to bullies
(via sciencedaily.com) Original source New research from Dartmouth takes a fresh look at game theory to show that being uncooperative can help people on the weaker side of a power dynamic achieve a more equal outcome -- and even inflict some loss on their abusive counterpart. The findings can be applied to help equalize the balance of power in labor negotiations, international relations and everyday interactions, as well as integrate cooperation into interconnected AI systems such as driverless cars.
Published Researchers develop digital test to directly measure HIV viral load
(via sciencedaily.com) Original source A milliliter of blood contains about 15 individual drops. For a person with human immunodeficiency virus (HIV), each drop of blood could contain anywhere from fewer than 20 copies of the virus to more than 500,000 copies. Called the viral load, this is what is measured to allow clinicians to understand how patients are responding to anti-viral medications and monitor potential progression. The time-consuming viral load testing needs to be repeated several times as a patient undergoes treatment. Now, a research team has developed a time and cost-efficient digital assay that can directly measure the presence of HIV in single drop of blood.
Published Researcher uses pressure to understand RNA dynamics
(via sciencedaily.com) Original source Just as space holds infinite mysteries, when we zoom in at the level of biomolecules (one trillion times smaller than a meter), there is still so much to learn. Scientists are studying the conformational landscapes of biomolecules and how they modulate cell function. When biomolecules receive certain inputs, it can cause the atoms to rearrange and the biomolecule to change shape. This change in shape affects their function in cells, so understanding conformational dynamics is critical for drug development.
Published The molecular control center of our protein factories
(via sciencedaily.com) Original source Researchers have deciphered a biochemical mechanism that ensures that newly formed proteins are processed correctly when they leave the cell's own protein factories. This solves a decade-old puzzle in protein sorting.
Published The clue is in the glue -- Nature's secret for holding it together
(via sciencedaily.com) Original source An obscure aquatic plant has helped to explain how plants avoid cracking up under the stresses and strains of growth.
Published Studying herpes encephalitis with mini-brains
(via sciencedaily.com) Original source The herpes simplex virus-1 can sometimes cause a dangerous brain infection. Combining an anti-inflammatory and an antiviral could help in these cases, report scientists.
Published Unraveling the connections between the brain and gut
(via sciencedaily.com) Original source Engineers designed a technology to probe connections between the brain and the digestive tract. Using fibers embedded with a variety of sensors, as well as optogenetic stimulation, the researchers could control neural circuits connecting the gut and the brain, in mice.
Published Now, every biologist can use machine learning
(via sciencedaily.com) Original source Scientists have built a new, comprehensive AutoML platform designed for biologists with little to no ML experience. New automated machine learning platform enables easy, all-in-one analysis, design, and interpretation of biological sequences with minimal coding. Their platform, called BioAutoMATED, can use sequences of nucleic acids, peptides, or glycans as input data, and its performance is comparable to other AutoML platforms while requiring minimal user input.
Published DNA can fold into complex shapes to execute new functions
(via sciencedaily.com) Original source DNA can mimic protein functions by folding into elaborate, three-dimensional structures, according to a new study.