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Categories: Biology: Molecular, Mathematics: General
Published Researchers reveal mechanism of protection against breast and ovarian cancer
(via sciencedaily.com) Original source Researchers have outlined the structure and function of a protein complex which is required to repair damaged DNA and protect against cancer.
Published Scientists discover new embryonic cell type that self-destructs to protect the developing embryo
(via sciencedaily.com) Original source Scientists have uncovered a new quality control system that removes damaged cells from early developing embryos.
Published The speed of life: A zoo of cells to study developmental time
(via sciencedaily.com) Original source Researchers have used an unprecedented stem cell zoo to compare six different mammalian species and their developmental time.
Published Tethering of shattered chromosomal fragments paves way for new cancer therapies
(via sciencedaily.com) Original source Scientists discover shattered chromosomal fragments are tethered together during cell division before being rearranged; destroying the tether may help prevent cancerous mutations.
Published Close up on aging reveals how different cell types in the body age at different pace
(via sciencedaily.com) Original source A team or researchers reports the first Aging Fly Cell Atlas (AFCA), a detailed characterization of the aging process in 163 distinct cell types in the laboratory fruit fly. Their in-depth analysis revealed that different cell types in the body age differently, each cell type following a process involving cell type-specific patterns. AFCA provides a valuable resource for researchers in the fruit fly and aging communities as a reference to study aging and age-related diseases and to evaluate the success of anti-aging strategies.
Published High-quality child care contributes to later success in science, math
(via sciencedaily.com) Original source Children who receive high-quality child care as babies, toddlers and preschoolers do better in science, technology, engineering and math through high school, and that link is stronger among children from low-income backgrounds, according to new research.
Published Scientists discover small RNA that regulates bacterial infection
(via sciencedaily.com) Original source Researchers have identified the major mechanism behind the transition between chronic and acute P. aeruginosa infections. Their research findings can inform the development of future treatments for life-threatening acute infections.
Published First illustration of the molecular machinery that makes cilia beat
(via sciencedaily.com) Original source The first image of the structures that power human cilia -- the tiny, hairlike projections that line our airways -- has now been produced and it could lead to much-needed treatments for people with rare cilial diseases.
Published A step toward safe and reliable autopilots for flying
(via sciencedaily.com) Original source Researchers developed a machine-learning technique that can autonomously drive a car or fly a plane through a very difficult 'stabilize-avoid' scenario, in which the vehicle must stabilize its trajectory to arrive at and stay within some goal region, while avoiding obstacles.
Published When water temperatures change, the molecular motors of cephalopods do too
(via sciencedaily.com) Original source Working with live squid hatchlings, scientists find the animals can tune their proteome on the fly in response to changes in ocean temperature via the unique process of RNA recoding. The findings inspire new questions about basic protein function.
Published Study unravels the mysteries of actin filament polarity
(via sciencedaily.com) Original source An electron microscopy study revealed key details of actin filaments, which are essential structural elements of cells and muscles.
Published Octopuses rewire their brains to adapt to seasonal temperature shifts
(via sciencedaily.com) Original source Octopuses don't thermoregulate, so their powerful brains are exposed to -- and potentially threatened by -- changes in temperature. Researchers report that two-spot octopuses adapt to seasonal temperature shifts by producing different neural proteins under warm versus cool conditions. The octopuses achieve this by editing their RNA, the messenger molecule between DNA and proteins. This rewiring likely protects their brains, and the researchers suspect that this unusual strategy is used widely amongst octopuses and squid.
Published A compound from fruit flies could lead to new antibiotics
(via sciencedaily.com) Original source Research shows that the natural peptide, called drosocin, protects fruit flies from bacterial infections by binding to ribosomes in bacteria. Once bound, drosocin prevents the ribosome from making new proteins.
Published Muscle fibers: An unexpected organization revealed
(via sciencedaily.com) Original source Researchers have just made the unexpected discovery of a novel organization of muscle fibers in Parophidion vassali, a fish that lives in the Mediterranean Sea and, like many fish, uses specialized muscles to produce sounds. This is an important discovery that could well change our understanding of muscle contraction.
Published New class of antibiotics to fight resistant bacteria
(via sciencedaily.com) Original source Health professionals are in urgent need of new antibiotics to tackle resistant bacteria. Researchers have now modified the chemical structure of naturally occurring peptides to develop antimicrobial molecules that bind to novel targets in the bacteria's metabolism.
Published Symbiotic and pathogenic fungi may use similar molecular tools to manipulate plants
(via sciencedaily.com) Original source Symbiotic and pathogenic fungi that interact with plants are distantly related and don't share many genetic similarities. Comparing plant pathogenic fungi and plant symbiotic fungi, scientists at the Sainsbury Laboratory Cambridge University (SLCU) have discovered that these remote relatives are using a similar group of proteins to manipulate and live within plants.
Published DNA damage repaired by antioxidant enzymes
(via sciencedaily.com) Original source In crisis, the nucleus calls antioxidant enzymes to the rescue. The nucleus being metabolically active is a profound paradigm shift with implications for cancer research.
Published Reading between the cracks: Artificial intelligence can identify patterns in surface cracking to assess damage in reinforced concrete structures
(via sciencedaily.com) Original source Researchers are trying to make the process more efficient and definitive by using artificial intelligence, combined with a classic mathematical method for quantifying web-like networks, to determine how damaged a concrete structure is, based solely on its pattern of cracking.
Published Engineers report low-cost human biomarker sensor designs
(via sciencedaily.com) Original source Researchers have developed a low-cost, RNA-based technology to detect and measure biomarkers, which can help decode the body's physiology. The presence of protein biomarkers can indicate chronic or acute conditions, from arthritis to cancer to bacterial infections, for which conventional tests can cost anywhere from $100 to upwards of $1,000. The new technology can perform the same measurement for about a dollar.
Published A protein mines, sorts rare earths better than humans, paving way for green tech
(via sciencedaily.com) Original source Rare earth elements, like neodymium and dysprosium, are a critical component to almost all modern technologies, from smartphones to hard drives, but they are notoriously hard to separate from the Earth's crust and from one another. Scientists have discovered a new mechanism by which bacteria can select between different rare earth elements, using the ability of a bacterial protein to bind to another unit of itself, or 'dimerize,' when it is bound to certain rare earths, but prefer to remain a single unit, or 'monomer,' when bound to others.