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Categories: Biology: Molecular, Ecology: Animals
Published Near-universal T cell immunity towards a broad range of bacteria
(via sciencedaily.com) Original source Typically T cells of the immune system respond to a specific feature (antigen) of a microbe, thereby generating protective immunity. Scientists have discovered an exception to this rule. Namely, a group of divergent bacterial pathogens, including pneumococci, all share a small highly conserved protein sequence, which is both presented and recognized by human T cells in a conserved population-wide manner.
Published Luring the virus into a trap
(via sciencedaily.com) Original source Viruses like influenza A and Ebola invade human cells in a number of steps. Research teams investigated the final stages of viral penetration using electron tomography and computer simulations. So-called fusion pores, through which the viral genome is released into the host cell, play a central role in these processes. If they can be prevented from forming, the virus is also blocked. The Heidelberg scientists describe previously unknown mechanisms, which might lead to new approaches to prevent infections.
Published Researchers reveal an ancient mechanism for wound repair
(via sciencedaily.com) Original source The study is the first to identify a damage response pathway that is distinct from but parallel to the classical pathway triggered by pathogens.
Published Newly sequenced hornet genomes could help explain invasion success
(via sciencedaily.com) Original source The genomes of two hornet species, the European hornet and the Asian hornet (or yellow-legged hornet) have been sequenced.
Published Researchers reveal a map to study novel form of cell-to-cell communication
(via sciencedaily.com) Original source An international team of researchers lays the foundation to examine how extracellular RNA and its carrier proteins found in bodily fluids function in a healthy as well as a diseased setting, potentially providing a means to accurately implement early detection and monitor disease processes.
Published Synthetic biology meets fashion in engineered silk
(via sciencedaily.com) Original source Engineers developed a method to create synthetic spider silk at high yields while retaining strength and toughness using mussel foot proteins.
Published Elephant seals drift off to sleep while diving far below the ocean surface
(via sciencedaily.com) Original source For the first time, scientists have recorded brain activity in a free-ranging, wild marine mammal, revealing the sleep habits of elephant seals during the months they spend at sea. The new findings show that while elephant seals may spend 10 hours a day sleeping on the beach during the breeding season, they average just 2 hours of sleep per day when they are at sea on months-long foraging trips. They sleep for about 10 minutes at a time during deep, 30-minute dives, often spiraling downward while fast asleep, and sometimes lying motionless on the seafloor.
Published Reinforcement learning: From board games to protein design
(via sciencedaily.com) Original source An AI strategy proven adept at board games like Chess and Go, reinforcement learning, has now been adapted for a powerful protein design program. The results show that reinforcement learning can do more than master board games. When trained to solve long-standing puzzles in protein science, the software excelled at creating useful molecules. In one experiment, proteins made with the new approach were found to be more effective at generating useful antibodies in mice than were previous methods. If this method is applied to the right research problems, it likely could accelerate progress in a variety of scientific fields.
Published Biologists discover bees to be brew masters of the insect world
(via sciencedaily.com) Original source Scientists have made a remarkable discovery about cellophane bees -- their microbiomes are some of the most fermentative known from the insect world. These bees, which are named for their use of cellophane-like materials to line their subterranean nests, are known for their fascinating behaviors and their important ecological roles as pollinators. Now, researchers have uncovered another aspect of their biology that makes them even more intriguing.
Published AI system can generate novel proteins that meet structural design targets
(via sciencedaily.com) Original source A new machine-learning system can generate protein designs with certain structural features, and which do not exist in nature. These proteins could be utilized to make materials that have similar mechanical properties to existing materials, like polymers, but which would have a much smaller carbon footprint.
Published Chitin from consuming insects can help both gut microbiota and global health
(via sciencedaily.com) Original source Increased insect consumption by humans may be better for both gut health and planetary health. Chitin (kai'tin) and healthy fats from insects appear to contribute to healthy gut microbiota and are strong sources of protein and nutrients, according to a recent paper.
Published Engineering the next generation of cell and gene therapies
(via sciencedaily.com) Original source Investigators are developing a novel way to treat amyotrophic lateral sclerosis (ALS) and retinitis pigmentosa using engineered stem cells that may eventually lead to personalized treatments.
Published Hungry eyes: Spiders lose vision when they're starving
(via sciencedaily.com) Original source Biologists have discovered that underfed jumping spiders lose light-sensitive cells that are key to their vision.
Published Chicken breeding in Japan dates back to fourth century BCE
(via sciencedaily.com) Original source Conclusive evidence of chicken breeding in the Yayoi period of Japan has been discovered from the Karako-Kagi site.
Published Simple addition to corn bran could boost grain's nutritional value 15-35%
(via sciencedaily.com) Original source What if, by adding a couple of cell layers inside a corn kernel, the grain could become significantly richer in essential nutrients like iron, zinc, and protein? Such an improvement could benefit people who rely on corn for a large portion of their diet, as in many parts of the global south.
Published Nature's chefs: Scientists propose food-making as means of understanding species interactions
(via sciencedaily.com) Original source An interdisciplinary group of researchers is proposing a new way to think of some interactions between species, classifying a variety of plants, animals and fungi as 'nature's chefs.' Specifically, nature's chefs are organisms that provide food -- or the illusion of food -- to other organisms. The concept offers a new perspective on species interactions, which can inform how people think about food across the tree of life as well as disparate research disciplines.
Published Study links 'stuck' stem cells to hair turning gray
(via sciencedaily.com) Original source Certain stem cells have a unique ability to move between growth compartments in hair follicles, but get stuck as people age and so lose their ability to mature and maintain hair color, a new study shows.
Published Why this bird flu is different: Scientists say new avian influenza requires urgent coordinated response
(via sciencedaily.com) Original source A new study tracks arrival and spread of highly pathogenic Avian Influenza (H5N1) decimating wild birds, impacting poultry and pushing up egg prices. The team found that the deadly impact on wild birds and a shift from seasonal to year-round infections signal dangerous changes in avian influenza in the U.S.
Published Loops, flags and tension in DNA
(via sciencedaily.com) Original source Two protein complexes carry the major responsibility for the spatial organization of chromosomes in our cell nuclei. DNA tension plays a surprising role in this. Nanoscientists now publish how they have visualized this.
Published New mechanism for DNA folding
(via sciencedaily.com) Original source A hitherto unknown mechanism for DNA folding is described in a new study. The findings provide new insights into chromosomal processes that are vital to both normal development and to prevent disease.