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Categories: Biology: Molecular, Ecology: Animals
Published hnRNPM, a guardian of the integrity of cellular protein production
(via sciencedaily.com) Original source Researchers have discovered that the protein hnRNPM prevents the cell from making mistakes while it is producing new proteins, which helps maintain the integrity of this vital process.
Published Editing without 'cutting': Molecular mechanisms of new gene-editing tool revealed
(via sciencedaily.com) Original source New research has determined the spatial structure of various processes of a novel gene-editing tool called 'prime editor.' Functional analysis based on these structures also revealed how a 'prime editor' could achieve reverse transcription, synthesizing DNA from RNA, without 'cutting' both strands of the double helix. Clarifying these molecular mechanisms contributes greatly to designing gene-editing tools accurate enough for gene therapy treatments.
Published Chicken feathers to deliver chemotherapy drugs and repair enzymes
(via sciencedaily.com) Original source A new method of drug delivery using proline, an amino acid found in chicken feathers and skin tissue, could be used to limit the side effects of chemotherapy and repair important enzymes, new research suggests.
Published Fatal attraction: When endangered species try to mate with domestic relatives, both wildlife and people lose
(via sciencedaily.com) Original source Sticks and stones aren't enough to thwart biological attraction, but sometimes those are the only tools available to pastoralists trying to prevent wildlife from eloping with their livestock. A new study brings awareness to both the human impacts of these encounters -- ranging from economic loss to death -- and conservation concerns for the wild animals that are often endangered.
Published Slugs and snails love the city, unlike other animals
(via sciencedaily.com) Original source Most native species avoid more urbanized areas of Los Angeles, but slugs and snails may actually prefer these environments, according to a new study.
Published Wild megalopolis: Study shows unexpected pockets of biodiversity pepper Los Angeles
(via sciencedaily.com) Original source Researchers, in partnership with the city of Los Angeles, have developed the urban association index to help identify how well or poorly individual wildlife species are doing in the city. The researchers found unexpected pockets of biodiversity deep in the city, but they say it will still be a challenge to elevate Los Angeles' overall level of biodiversity.
Published Marine Protected Areas don't line up with core habitats of rare migratory fish, finds new research
(via sciencedaily.com) Original source 62% of Marine Protected Areas (MPAs) designated to protect rare migratory fish species are outside of their core habitats, according to a new modeling study.
Published Intermittent fasting shows promise in improving gut health, weight management
(via sciencedaily.com) Original source Participants following an intermittent fasting and protein-pacing regimen, which involves evenly spaced protein intake throughout the day, saw better gut health, weight loss and metabolic responses. These benefits were notably greater than those seen with simple calorie restriction. The findings could advance our understanding of the relationship between the gut microbiome and metabolism and improve strategies for managing obesity.
Published Smarter foragers do not forage smarter
(via sciencedaily.com) Original source Why do primates have big brains? In the Panamanian rainforest, scientists pitted large-brained primates against smaller-brained mammals to find out who was the smartest forager.
Published Mechanisms for selective multiple sclerosis treatment strategy
(via sciencedaily.com) Original source Researchers have demonstrated how B cells infected with the Epstein-Barr virus (EBV) can contribute to a pathogenic, inflammatory phenotype that contributes to multiple sclerosis (MS); the group has also shown how these problematic B cells can be selectively targeted in a way that reduces the damaging autoimmune response of multiple sclerosis.
Published 'Cloaked' proteins deliver cancer-killing therapeutics into cells
(via sciencedaily.com) Original source Scientists have designed a way to 'cloak' proteins in a generalized technique that could lead to repurposing things like antibodies for biological research and therapeutic applications.
Published Tracking animals without markers in the wild
(via sciencedaily.com) Original source Researchers developed a computer vision framework for posture estimation and identity tracking which they can use in indoor environments as well as in the wild. They have thus taken an important step towards markerless tracking of animals in the wild using computer vision and machine learning.
Published Genetic mosaicism more common than thought
(via sciencedaily.com) Original source Researchers found that approximately one in 40 human bone marrow cells carry massive chromosomal alterations without causing any apparent disease or abnormality. Even so-called normal cells carry all sorts of genetic mutations, meaning there are more genetic differences between individual cells in our bodies than between different human beings. The discovery was enabled by a single-cell sequencing technology called Strand-seq, a unique DNA sequencing technique that can reveal subtle details of genomes in single cells that are too difficult to detect with other methods.
Published Entomologist sheds light on 250-year-old mystery of the German cockroach
(via sciencedaily.com) Original source Entomologists have solved the 250-year-old origin puzzle of the most prevalent indoor urban pest insect on the planet: the German cockroach. The team's research findings, representing the genomic analyses of over 280 specimens from 17 countries and six continents, show that this species evolved some 2,100 years ago from an outdoor-living species in Asia.
Published High H5N1 influenza levels found in mice given raw milk from infected dairy cows
(via sciencedaily.com) Original source Mice administered raw milk samples from dairy cows infected with H5N1 influenza experienced high virus levels in their respiratory organs and lower virus levels in other vital organs, according to new findings. The results suggest that consumption of raw milk by animals poses a risk for H5N1 infection and raises questions about its potential risk in humans.
Published Observing mammalian cells with superfast soft X-rays
(via sciencedaily.com) Original source Researchers have developed a new technique to view living mammalian cells. The team used a powerful laser, called a soft X-ray free electron laser, to emit ultrafast pulses of illumination at the speed of femtoseconds, or quadrillionths of a second. With this they could capture images of carbon-based structures in living cells for the first time, before the soft X-ray radiation damaged them.
Published Caterpillars can detect their predators by the static electricity they emit
(via sciencedaily.com) Original source Caterpillars respond defensively to electric fields similar to those emitted by their natural predators, scientists have found.
Published New 'atlas' provides unprecedented insights on how genes function in early embryo development
(via sciencedaily.com) Original source Biologists have provided new insights on a longstanding puzzle in biology: How complex organisms arise from a single fertilized cell. Producing a new 'gene atlas' with 4-D imaging, the researchers captured unprecedented insights on how embryonic development unfolds.
Published Designing a better nest to help endangered turtles
(via sciencedaily.com) Original source With Ontario's eight species of turtles considered at risk, a new nest designed by researchers has the potential to significantly bolster their struggling populations. The habitat is the first designed for turtles in rock barren landscapes, such as the research site around Georgian Bay. It uses moss and lichen. The researchers found that the design provided a more stable environment for incubating eggs compared to natural sites, where the probability of an egg hatching was only 10 per cent compared to 41 per cent in the created site.
Published Novel approach to interrogate tissue-specific protein-protein interactions
(via sciencedaily.com) Original source Multicellular organisms, like animals and plants, have complex cells with diverse functions. This complexity arises from the need for cells to produce distinct proteins that interact with each other. This interaction is crucial for cells to carry out their specific tasks and to form complex molecular machinery. However, our current understanding of such protein-protein interactions often lacks cellular contexts because they were usually studied in an in vitro system or in cells isolated from their tissue environment. Effective methods to investigate protein-protein interactions in a tissue-specific manner are largely missing.