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Categories: Biology: Molecular, Ecology: Endangered Species
Published Proteins and fats can drive insulin production for some, paving way for tailored nutrition



When it comes to managing blood sugar levels, most people think about counting carbs. But new research shows that, for some, it may be just as important to consider the proteins and fats in their diet. The study is the first large-scale comparison of how different people produce insulin in response to each of the three macronutrients: carbohydrates (glucose), proteins (amino acids) and fats (fatty acids). The findings reveal that production of the blood sugar-regulating hormone is much more dynamic and individualized than previously thought, while showing for the first time a subset of the population who are hyper-responsive to fatty foods.
Published Study illuminates cues algae use to 'listen' to their environment



New research shows how a small group of single-celled algae are able to use chemical cues to communicate stress information. Understanding this ability, once thought unique to plants, helps illuminate the complex evolutionary history of plants and algae.
Published Degradation of cell wall key in the spread of antibiotic resistance



A study provides new clues in the understanding of how antibiotic resistance spreads. The study shows how an enzyme breaks down the bacteria's protective outer layer, the cell wall, and thus facilitates the transfer of genes for resistance to antibiotics.
Published Researchers thwart resistant bacteria's strategy



Bacteria are experts at evolving resistance to antibiotics. One resistance strategy is to cover their cell walls in sticky and gooey biofilm that antibiotics cannot penetrate. A new discovery could put a stop to this strategy.
Published The evidence is mounting: humans were responsible for the extinction of large mammals



Human hunting, not climate change, played a decisive role in the extinction of large mammals over the last 50,000 years. This conclusion comes from researchers who reviewed over 300 scientific articles from many different fields of research.
Published Choose where to plant energy crops wisely to minimise loss of biodiversity



In the fight to protect biodiversity and limit climate change, the world will reap what it sows.
Published This desert moss has the potential to grow on Mars



The desert moss Syntrichia caninervis is a promising candidate for Mars colonization thanks to its extreme ability to tolerate harsh conditions lethal to most life forms. The moss is well known for its ability to tolerate drought conditions, but researchers now report that it can also survive freezing temperatures as low as 196 C, high levels of gamma radiation, and simulated Martian conditions involving these three stressors combined. In all cases, prior dehydration seemed to help the plants cope.
Published Projected loss of brown macroalgae and seagrasses with global environmental change



Researchers predict that climate change will drive a substantial redistribution of brown seaweeds and seagrasses at the global scale. The projected changes are alarming due to the fundamental role seaweeds and seagrasses in coastal ecosystems and provide evidence of the pervasive impacts of climate change on marine life.
Published Groundbreaking discovery: Zinc can make crop yields more climate-resilient



Climate change, drought, increased temperature and other stressors challenge agricultural sustainability. Researchers have now made an unexpected discovery: zinc plays a pivotal role in the plant response to abiotic stress. This groundbreaking discovery not only sheds light on the intricate mechanisms of plant growth but also holds promise for revolutionizing crop resilience, especially in legume-based agriculture.
Published New deep-learning model outperforms Google AI system in predicting peptide structures



Researchers have developed a deep-learning model, called PepFlow, that can predict all possible shapes of peptides -- chains of amino acids that are shorter than proteins, but perform similar biological functions. Peptides are known to be highly flexible, taking on a wide range of folding patterns, and are thus involved in many biological processes of interest to researchers in the development of therapeutics.
Published Last surviving woolly mammoths were inbred but not doomed to extinction



The last population of woolly mammoths was isolated on Wrangel Island off the coast of Siberia 10,000 years ago, when sea levels rose and cut the mountainous island off from the mainland. A new genomic analysis reveals that the isolated mammoths, who lived on the island for the subsequent 6,000 years, originated from at most 8 individuals but grew to 200--300 individuals within 20 generations. The researchers report that the Wrangel Island mammoths' genomes showed signs of inbreeding and low genetic diversity but not to the extent that it can explain their ultimate (and mysterious) extinction.
Published A promising weapon against measles



What happens when measles virus meets a human cell? The viral machinery unfolds in just the right way to reveal key pieces that let it fuse itself into the host cell membrane.
Published Potent therapy candidate for fatal prion diseases



Scientists have developed a gene-silencing tool that shows promise as a therapy against fatal prion diseases. The tool, a streamlined epigenetic editor, paves the way for a new class of genetic approaches to treat certain diseases.
Published New, holistic way to teach synthetic biology



Synthetic biology combines principles from science, engineering and social science, creating emerging technologies such as alternative meats and mRNA vaccines; Deconstructing synthetic biology across scales gives rise to new approach to uniting traditional disciplines; Case studies offer a modular, accessible approach to teaching at different institutions.
Published From takeoff to flight, the wiring of a fly's nervous system is mapped



Although a fly's motor neurons are few, it performs remarkable aerial and terrestrial feats. A wiring diagram recently created of the motor circuits in the central nervous system of the fruit fly is providing detailed information on how the nerve coordination of leg movements differs from that controlling the wings. Such studies reveal the unexpected complexity of the fly's tiny motor system. They also advance the understanding of how the central nervous system in animals coordinates individual muscles to carry out a variety of behaviors.
Published Cell division: Before commitment, a very long engagement



Before a cell commits fully to the process of dividing itself into two new cells, it may ensure the appropriateness of its commitment by staying for many hours -- sometimes more than a day -- in a reversible intermediate state, according to a new discovery. Their revelation of this fundamental feature of biology includes details of its mechanisms and dynamics, which may inform the development of future therapies targeting cancers and other diseases.
Published New tool enables faster, more cost-effective genome editing of traits to improve agriculture sustainability



New research had the goal of reducing the time and cost it takes to bring an improved crop to the marketplace to improve agriculture sustainability.
Published Unlocking the world of bacteria



Bacteria possess unique traits with great potential for benefiting society. However, current genetic engineering methods to harness these advantages are limited to a small fraction of bacterial species. A team has now introduced a novel approach that can make many more bacteria amenable to genetic engineering. Their method, called IMPRINT, uses cell-free systems to enhance DNA transformation across various bacterial strains.
Published The on-and-off affair in DNA



Researchers have discovered that in thale cresses histone H3 lysine-9 (H3K9) methylation, conventionally thought to be a mark of turning off gene transcription, can also turn on gene expression via the interactions of two other proteins and histone marks. The molecular mechanisms demonstrate that rather than functioning as a simple 'off switch,' H3K9 methylation is more like a 'dimmer switch' that fine-tunes DNA transcription. The discovery suggests there might be similar mechanisms in other organisms, too.
Published Slipping a note to a neighbor: The cellular way



Study reveals how drug molecules bind in channels between neighboring cells, changing intercellular communication.