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Categories: Biology: Molecular, Ecology: Endangered Species
Published A novel pathway regulating lipid biosynthesis by fatty acids



Sterol regulatory element-binding proteins (SREBPs) play a crucial role in lipid biosynthesis. In a recent study, researchers identified a novel cleavage enzyme of SREBP-1c, a key player in fatty acid biosynthesis. Moreover, the team unveiled, for the first time, that the biosynthesis process of fatty acid in the liver is activated by saturated fatty acids and inhibited by polyunsaturated fatty acids, providing new insights into the intricate workings of this cleavage system.
Published New insights into what helps Salmonella cause infections



In a new study, researchers have discovered how a system of proteins, called TamAB, helps Salmonella survive under the harsh conditions inside macrophages.
Published 3D in vitro human atherosclerosis model for high-throughput drug screening



A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease, researchers report.
Published Researchers create light-powered yeast, providing insights into evolution, biofuels, cellular aging



Researchers have engineered one of the world's first yeast cells able to harness energy from light, expanding our understanding of the evolution of this trait -- and paving the way for advancements in biofuel production and cellular aging.
Published New rice lines for Africa offer virus protection



The so-called Rice Yellow Mottle Virus (for short: RYMV) is responsible for high crop losses in Africa, particularly among small-scale farmers. A research team has now produced rice lines that are resistant to the disease by means of genome editing. The rice varieties are a preliminary step toward being able to generate resistant locally adapted elite varieties for small-scale food producers in Africa.
Published Spying on a shape-shifting protein



Researchers are using crystallography to gain a better understanding of how proteins shapeshift. The knowledge can provide valuable insight into stopping and treating diseases.
Published Human activity facilitates invasive plants' colonization in Mediterranean ecosystems



Some invasive plants can form persistent banks of seeds that remain under the soil for years, and this makes their eradication practically impossible. Over time, this invisible population of large quantities of living, buried plants -- in seed form -- will reoccupy ecosystems and displace the typical flora of the natural environment.
Published Study uncovers potential origins of life in ancient hot springs



A research team investigated how the emergence of the first living systems from inert geological materials happened on the Earth, more than 3.5 billion years ago. Scientists found that by mixing hydrogen, bicarbonate, and iron-rich magnetite under conditions mimicking relatively mild hydrothermal vent results in the formation of a spectrum of organic molecules, most notably including fatty acids stretching up to 18 carbon atoms in length.
Published Even the oldest eukaryote fossils show dazzling diversity and complexity



The sun has just set on a quiet mudflat in Australia's Northern Territory; it'll set again in another 19 hours. A young moon looms large over the desolate landscape. No animals scurry in the waning light. No leaves rustle in the breeze. No lichens encrust the exposed rock. The only hint of life is some scum in a few puddles and ponds. And among it lives a diverse microbial community of our ancient ancestors.
Published Thermal vision shows endangered numbats feel the heat of warming climate



Research using thermal imaging of numbats in Western Australia has found that during hot weather the endangered animals are limited to as little as ten minutes of activity in the sun before they overheat to a body temperature of greater than 40 C.
Published Lab-grown retinas explain why people see colors dogs can't



With human retinas grown in a petri dish, researchers discovered how an offshoot of vitamin A generates the specialized cells that enable people to see millions of colors, an ability that dogs, cats, and other mammals do not possess. The findings increase understanding of color blindness, age-related vision loss, and other diseases linked to photoreceptor cells. They also demonstrate how genes instruct the human retina to make specific color-sensing cells, a process scientists thought was controlled by thyroid hormones.
Published Protein complex discovered to control DNA repair



The repair of damage to genetic material (DNA) in the human body is carried out by highly efficient mechanisms that have not yet been fully researched. A scientific team has now discovered a previously unrecognized control point for these processes. This could lead to a new approach for the development of cancer therapies aimed at inhibiting the repair of damaged cancer cells.
Published Toxic algae blooms: Study assesses potential health hazards to humans



Water samples from 20 sites were tested using a panel of immortalized human cell lines corresponding to the liver, kidney and brain to measure cytotoxicity. Results show that each control toxin induced a consistent pattern of cytotoxicity in the panel of human cell lines assayed. Known toxins were seen only during blooms. Because cell toxicity was seen in the absence of blooms, it suggests that there might be either emergent toxins or a combination of toxins present at those times. Findings suggest that other toxins with the potential to be harmful to human health may be present in the lagoon.
Published A new type of plant metalloreductase maintains root growth under low phosphorus



Phosphorus is essential for undisturbed plant growth and development. However, in many soils, phosphorus is only poorly available. One mechanism used by plants to increase phosphorus availability is the release of malate, an organic acid, which can form complexes with iron or aluminium in the soil, thereby liberating sorbed phosphate. However, this response can also result in iron overaccumulation, which can inhibit root growth.
Published Red deer populations in Europe: More influenced by humans than by wolves and other predators



A new study shows that human hunting and land use have a decisive influence on red deer density in Europe. Red deer density is only reduced when wolves, lynx and bears co-occur at the same site.
Published Iron influences plant immunity and may promote resiliency against climate change



Researchers discovered that plants manage iron deficiency without helping 'bad' bacteria thrive by eliminating the molecular signal for iron deficiency, and that the iron deficiency signaling pathway and the plant immune system are deeply intertwined. Their findings provide a new target for boosting plant resilience in the face of climate change, and offer new insight into plant and animal microbiomes.
Published Plant warfare: The crucial function of Nrc proteins in tomato defense mechanisms



New research delves into the intricate defense mechanisms of tomatoes against the notorious bacterial pathogen, Pseudomonas syringae pv. tomato (Pst). It's a classic tale of nature's arms race: as pathogens evolve to outsmart plant defenses, plants counter with more sophisticated immune responses.
Published With only the pawprints, researchers study elusive bobcat



With DNA recovered from animal tracks, scientists revealed information about the ancestry and microbial community of bobcats without having to sample the animal directly.
Published Smart skin bacteria are able to secrete and produce molecules to treat acne



An experimental study has shown that a type of skin bacterium can efficiently be engineered to produce a protein to regulate sebum production. This application could treat acne without compromising the homeostasis of the entire skin microbiome.
Published Large-scale mapping of pig genes could pave the way for new human medicines



Researchers have carried out complex genetic analyses of hundreds of pigs and humans to identify differences and similarities. This new knowledge can be used to ensure healthier pigs for farmers and can help the pharmaceutical industry breed better laboratory pigs for testing new medicines.