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Categories: Biology: Molecular, Ecology: Sea Life
Published New deep-learning model outperforms Google AI system in predicting peptide structures
(via sciencedaily.com) Original source Researchers have developed a deep-learning model, called PepFlow, that can predict all possible shapes of peptides -- chains of amino acids that are shorter than proteins, but perform similar biological functions. Peptides are known to be highly flexible, taking on a wide range of folding patterns, and are thus involved in many biological processes of interest to researchers in the development of therapeutics.
Published To protect corals from summer heatwaves, we should help their microbial symbionts evolve heat tolerance in the lab
(via sciencedaily.com) Original source Most coral reef restoration efforts involve restocking reefs with nursery-grown corals. However, if these corals are of the same stock as their wild counterparts, they will be equally vulnerable to the heat stress that caused the bleaching event in the first place. Researchers discuss the potential of improving corals' chances by inducing the evolution of heat tolerance in their symbionts -- the mutualistic microbes that provide corals with nutrients in exchange for shelter and that are expelled during coral bleaching.
Published Pacific cod can't rely on coastal safe havens for protection during marine heat waves
(via sciencedaily.com) Original source During recent periods of unusually warm water in the Gulf of Alaska, young Pacific cod in near shore safe havens where they typically spend their adolescence did not experience the protective effects those areas typically provide, a new study found.
Published A promising weapon against measles
(via sciencedaily.com) Original source What happens when measles virus meets a human cell? The viral machinery unfolds in just the right way to reveal key pieces that let it fuse itself into the host cell membrane.
Published Prehistoric 'Pompeii' discovered: Most pristine trilobite fossils ever found shake up scientific understanding of the long extinct group
(via sciencedaily.com) Original source Researchers have described some of the best-preserved three-dimensional trilobite fossils ever discovered. The fossils, which are more than 500 million years old, were collected in the High Atlas of Morocco and are being referred to by scientists as 'Pompeii' trilobites due to their remarkable preservation in ash.
Published Under pressure: How comb jellies have adapted to life at the bottom of the ocean
(via sciencedaily.com) Original source Researchers have studied the cell membranes of ctenophores ('comb jellies') and found they had unique lipid structures that allow them to live under intense pressure.
Published Potent therapy candidate for fatal prion diseases
(via sciencedaily.com) Original source Scientists have developed a gene-silencing tool that shows promise as a therapy against fatal prion diseases. The tool, a streamlined epigenetic editor, paves the way for a new class of genetic approaches to treat certain diseases.
Published New, holistic way to teach synthetic biology
(via sciencedaily.com) Original source Synthetic biology combines principles from science, engineering and social science, creating emerging technologies such as alternative meats and mRNA vaccines; Deconstructing synthetic biology across scales gives rise to new approach to uniting traditional disciplines; Case studies offer a modular, accessible approach to teaching at different institutions.
Published Why the harsh Snowball Earth kick-started our earliest multicellular ancestors
(via sciencedaily.com) Original source Why did multicellularity arise? Solving that mystery may help pinpoint life on other planets and explain the vast diversity and complexity seen on Earth today, from sea sponges to redwoods to human society. A new article shows how specific physical conditions -- especially ocean viscosity and resource deprivation -- during the global glaciation period known as Snowball Earth could have driven eukaryotes to turn multicellular.
Published From takeoff to flight, the wiring of a fly's nervous system is mapped
(via sciencedaily.com) Original source Although a fly's motor neurons are few, it performs remarkable aerial and terrestrial feats. A wiring diagram recently created of the motor circuits in the central nervous system of the fruit fly is providing detailed information on how the nerve coordination of leg movements differs from that controlling the wings. Such studies reveal the unexpected complexity of the fly's tiny motor system. They also advance the understanding of how the central nervous system in animals coordinates individual muscles to carry out a variety of behaviors.
Published Cell division: Before commitment, a very long engagement
(via sciencedaily.com) Original source Before a cell commits fully to the process of dividing itself into two new cells, it may ensure the appropriateness of its commitment by staying for many hours -- sometimes more than a day -- in a reversible intermediate state, according to a new discovery. Their revelation of this fundamental feature of biology includes details of its mechanisms and dynamics, which may inform the development of future therapies targeting cancers and other diseases.
Published Unlocking the world of bacteria
(via sciencedaily.com) Original source Bacteria possess unique traits with great potential for benefiting society. However, current genetic engineering methods to harness these advantages are limited to a small fraction of bacterial species. A team has now introduced a novel approach that can make many more bacteria amenable to genetic engineering. Their method, called IMPRINT, uses cell-free systems to enhance DNA transformation across various bacterial strains.
Published The on-and-off affair in DNA
(via sciencedaily.com) Original source Researchers have discovered that in thale cresses histone H3 lysine-9 (H3K9) methylation, conventionally thought to be a mark of turning off gene transcription, can also turn on gene expression via the interactions of two other proteins and histone marks. The molecular mechanisms demonstrate that rather than functioning as a simple 'off switch,' H3K9 methylation is more like a 'dimmer switch' that fine-tunes DNA transcription. The discovery suggests there might be similar mechanisms in other organisms, too.
Published Future risk of coral bleaching set to intensify globally
(via sciencedaily.com) Original source Researchers have projected future marine heatwaves will cause coral reefs to be at severe risk of bleaching for longer periods than previously seen.
Published Ocean's loss of oxygen caused massive Jurassic extinction: Could it happen again?
(via sciencedaily.com) Original source Researchers have found a chemical clue in Italian limestone that explains a mass extinction of marine life in the Early Jurassic period, 183 million years ago. Volcanic activity pumped out CO2, warming oceans and lowering their oxygen levels. The findings may foretell the impact climate change and oxygen depletion might have on today's oceans.
Published Slipping a note to a neighbor: The cellular way
(via sciencedaily.com) Original source Study reveals how drug molecules bind in channels between neighboring cells, changing intercellular communication.
Published Towards non-toxic antifouling agents: A novel method for total synthesis of scabrolide F
(via sciencedaily.com) Original source Norcembranolide diterpenes, isolated from the soft corals of the genus Sinularia, are important compounds for the development of new drugs, owing to their diverse biological activities. However, total synthesis methods for these compounds are scarce. Now, a team of researchers has achieved the total synthesis of scabrolide F, a norcembranolide diterpene. They also revealed its non-toxic antifouling properties. This novel method can lead to the development of new drugs and antifouling agents.
Published Plankton researchers urge their colleagues to mix it up
(via sciencedaily.com) Original source A new article encourages researchers to focus their attention on mixoplankton, providing a set of methodologies to help expand our understanding of this critically important component of the marine ecosystem.
Published Revealing the dynamic choreography inside multilayer vesicles
(via sciencedaily.com) Original source Our cells and the machinery inside them are engaged in a constant dance. This dance involves some surprisingly complicated choreography within the lipid bilayers that comprise cell membranes and vesicles -- structures that transport waste or food within cells. In a recent paper, researchers shed some light on how these vesicles self-assemble, knowledge that could help scientists design bio-inspired vesicles for drug-delivery or inspire them to create life-like synthetic materials.
Published Zebrafish reveal how bioelectricity shapes muscle development
(via sciencedaily.com) Original source New research describes how nerve cells and muscle cells communicate through electrical signals during development -- a phenomenon known as bioelectricity. The communication, which takes place via specialized channels between cells, is vital for proper development and behavior. The study identifies specific genes that control the process, and pins down what happens when it goes wrong. The finding offers clues to the genetic origins of muscle disorders in humans.