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Categories: Biology: Molecular, Ecology: Sea Life
Published New research uncovers biological drivers of heart disease risk
(via sciencedaily.com) Original source Over the past 15 years, researchers have identified hundreds of regions in the human genome associated with heart attack risk. However, researchers lack efficient ways to explore how these genetic variants are molecularly connected to cardiovascular disease, limiting efforts to develop therapeutics. To streamline analysis of hundreds of genetic variants associated with coronary artery disease (CAD), a team of researchers combined multiple sequencing and experimental techniques to map the relationship between known CAD variants and the biological pathways they impact.
Published Gut microbiome changes during pregnancy may influence immune system response
(via sciencedaily.com) Original source A new study identifies numerous pathways by which the gut microbiome may change the immune system.
Published How kelp forests persisted through the large 2014-2016 Pacific marine heatwave
(via sciencedaily.com) Original source New research reveals that denser, and more sheltered, kelp forests can withstand serious stressors amid warming ocean temperatures.
Published New approach to tackling bacterial infections identified
(via sciencedaily.com) Original source Researchers have identified a new approach to controlling bacterial infections. The team found a way to turn on a vital bacterial defense mechanism to fight and manage bacterial infections. The defense system, called cyclic oligonucleotide-based antiphage signaling system (CBASS), is a natural mechanism used by certain bacteria to protect themselves from viral attacks. Bacteria self-destruct as a means to prevent the spread of virus to other bacterial cells in the population.
Published Researchers discover key to molecular mystery of how plants respond to changing conditions
(via sciencedaily.com) Original source A team of researchers recently published a pioneering study that answers a central question in biology: how do organisms rally a wide range of cellular processes when they encounter a change -- either internally or in the external environment -- to thrive in good times or survive the bad times? The research, focused on plants, identifies the interactions between four compounds: pectin, receptor proteins FERONIA and LLG1 and the signal RALF peptide.
Published Scientists develop new biocontainment method for industrial organisms
(via sciencedaily.com) Original source Researchers have developed a new biocontainment method for limiting the escape of genetically engineered organisms used in industrial processes.
Published Remarkable cellular architecture and phylogenetic position of the mysterious arm-swinging protist meteora sporadica
(via sciencedaily.com) Original source Researchers studied in detail the strange protist Meteora sporadica, which swings its two lateral arms back and forth. The results of the study indicated that M. sporadica has a complex cytoskeleton that is closely related to Hemimastigophora, a group of organisms considered to be one of the deepest branches of eukaryotes.
Published Extra fingers and hearts: Pinpointing changes to our genetic instructions that disrupt development
(via sciencedaily.com) Original source Scientists can now predict which single-letter changes to the DNA within our genomes will alter genetic instructions and disrupt development, leading to changes such as the growth of extra digits and hearts. Such knowledge opens the door to predictions of which enhancer variants underlie disease in order to harness the full potential of our genomes for better human health.
Published Number of shark bites consistent with recent trends, with small spike in fatalities
(via sciencedaily.com) Original source There was an increase in the number of unprovoked shark attacks worldwide and an uptick in fatalities in 2023 compared to the previous year. A scientific database of global shark attacks, confirmed 69 unprovoked bites in 2023. Although this is higher than the most recent five-year average of 63 attacks, the data remain consistent with long-term trends.
Published Computer-engineered DNA to study cell identities
(via sciencedaily.com) Original source A new computer program allows scientists to design synthetic DNA segments that indicate, in real time, the state of cells. It will be used to screen for anti-cancer or viral infections drugs, or to improve gene and cell-based immunotherapies.
Published Small but mighty -- study highlights the abundance and importance of the ocean's tiniest inhabitants
(via sciencedaily.com) Original source New research sheds light on tiny plankton, which measure less than 0.02mm in diameter but can make up more than 70% of the plankton biomass found in the ocean.
Published Vitamin B12 adaptability in Antarctic algae has implications for climate change, life in the Southern Ocean
(via sciencedaily.com) Original source The algae P. antarctica has two forms of the enzyme that makes the amino acid methionine, one needing B12, and one that is slower, but doesn't need it. This means it has the ability to adapt and survive with low B12 availability. The presence of the MetE gene in P. antarctica gives the algae the ability to adapt to lower vitamin B12 availability, giving it a potential advantage to bloom in the early austral spring when bacterial production is low. P. antarctica takes in the CO2 and releases oxygen through photosynthesis. Understanding its ability to grow in environments with low vitamin B12 availability can help climate modelers make more accurate predictions.
Published Scientists see an ultra-fast movement on surface of HIV virus
(via sciencedaily.com) Original source Seeing a glycoprotein on the envelope of the HIV virus snap open and shut in mere millionths of a second is giving investigators a new handle on the surface of the virus that could lead to broadly neutralizing antibodies for an AIDS vaccine. Being able to attach an antibody specifically to this little structure that would prevent it from popping open would be key.
Published Mechanism discovered that protects tissue after faulty gene expression
(via sciencedaily.com) Original source A study has identified a protein complex that is activated by defects in the spliceosome, the molecular scissors that process genetic information. Future research could lead to new therapeutic approaches to treat diseases caused by faulty splicing.
Published Disrupted cellular function behind type 2 diabetes in obesity
(via sciencedaily.com) Original source Disrupted function of 'cleaning cells' in the body may help to explain why some people with obesity develop type 2 diabetes, while others do not. A study describes this newly discovered mechanism.
Published A clutch stretch goes a long way
(via sciencedaily.com) Original source New results reveal a new mode of force transmission in which dynamic molecular stretching bridges the extracellular matrix and flowing F-actin moving at different speeds. This discovery underscores the necessity of molecular elasticity and random coupling for sufficiently transmitting force. The findings also call for revising the role of molecular unfolding.
Published Clown anemonefish seem to be counting bars and laying down the law
(via sciencedaily.com) Original source We often think of fish as carefree swimmers in the ocean, reacting to the world around them without much forethought. However, new research suggests that our marine cousins may be more cognizant than we credit them for. Fish may be counting vertical bars on intruders to determine their threat level, and to inform the social hierarchy governing their sea anemone colonies.
Published Tidal landscapes a greater carbon sink than previously thought
(via sciencedaily.com) Original source Mangroves and saltmarshes sequester large amounts of carbon, mitigating the greenhouse effect. New research shows that these environments are perhaps twice as effective as previously thought.
Published Plant receptors that control immunity and development share a common origin
(via sciencedaily.com) Original source Researchers have traced the origin and evolutionary trajectory of plant immune receptors. Their discovery will make it easier to identify immune receptor genes from genomic information and could help in the development of pathogen-resistant crops.
Published Gut bacteria can process dietary fiber into an anti-allergy weapon
(via sciencedaily.com) Original source Short-chain fatty acids (SCFAs), which are produced by gut bacteria from dietary fiber, regulate our immune system, but the mechanism of their action remains unknown. In a recent study, researchers investigated how SCFAs interact with mast cells, a type of white blood cell that plays a central role in allergic reactions. Their findings and insights could lead to innovative and effective anti-allergy medications, supplements, and diets, paving the way for healthier lives.