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Categories: Biology: Molecular, Ecology: Sea Life
Published Machine learning reveals sources of heterogeneity among cells in our bodies
(via sciencedaily.com) Original source A team of scientists discovered the secrets of cell variability in our bodies. The findings of this research are expected to have far-reaching effects, such as improvement in the efficacy of chemotherapy treatments, or set a new paradigm in the study of antibiotic-resistant bacteria.
Published Tiny AI-based bio-loggers revealing the interesting bits of a bird's day
(via sciencedaily.com) Original source Researchers have developed a bio-logger for seabirds that enables long-term observation of rare behaviors. The bio-logger employs low-power depth sensors and accelerometers to identify rare behavior using a light-weight outlier detection model and records the behavior in a 5-min video. Observations using the bio-loggers on Streaked Shearwaters revealed novel aspects of head-shaking and foraging strategies. This approach will enable a wider range of animal behaviors in various environments to be observed.
Published Glowing COVID-19 diagnostic test prototype produces results in one minute
(via sciencedaily.com) Original source Cold, flu and COVID-19 season brings that now-familiar ritual: swab, wait, look at the result. But what if, instead of taking 15 minutes or more, a test could quickly determine whether you have COVID-19 with a glowing chemical? In a new study, researchers describe a potential COVID-19 test inspired by bioluminescence. Using a molecule found in crustaceans, they have developed a rapid approach that detects SARS-CoV-2 protein comparably to one used in vaccine research.
Published Study uncovers mechanics of machete-like 'tail-whipping' in thresher sharks
(via sciencedaily.com) Original source Like Indiana Jones, thresher sharks have mastered the art of the whip using their tails. Now, new research provides intricate details showing that vertebrae anatomy might support the mechanics of extreme body bending in thresher sharks, enabling these expert hunters to weaponize their tails. Using micro-CT scanning similar to CAT scans in humans, and two-dimensional shape analysis, results of the study suggest vertebral anatomy and mineralized microstructure meet the demands required for fast swimming and tail-whipping behavior seen in these species.
Published New technology for conducting deep-sea research on fragile organisms
(via sciencedaily.com) Original source Scientists have successfully demonstrated new technologies that can obtain preserved tissue and high-resolution 3D images within minutes of encountering some of the most fragile animals in the deep ocean.
Published Pacific kelp forests are far older that we thought
(via sciencedaily.com) Original source Fossils of kelp along the Pacific Coast are rare. Until now, the oldest fossil dated from 14 million years ago, leading to the view that today's denizens of the kelp forest -- marine mammals, urchins, sea birds -- coevolved with kelp. A recent amateur discovery pushes back the origin of kelp to 32 million years ago, long before these creatures appeared. A new analysis suggests the first kelp grazers were extinct, hippo-like animals called desmostylians.
Published Unraveling the role of supersulfides in regulating mitochondrial function and longevity
(via sciencedaily.com) Original source Supersulfides, many of which are produced by cysteinyl-tRNA synthetase (CARS), are essential compounds across many different lifeforms. However, the precise physiological roles of CARS-produced supersulfide are unclear. Now, using a strategically engineered yeast mutant with a deficient CARS gene, researchers from Japan have shown that supersulfides control cell longevity by mediating mitochondrial energy metabolism and regulating protein quality.
Published Key moment in the evolution of life on Earth captured in fossils
(via sciencedaily.com) Original source New research has precisely dated some of the oldest fossils of complex multicellular life in the world, helping to track a pivotal moment in the history of Earth when the seas began teeming with new lifeforms -- after four billion years of containing only single-celled microbes.
Published Bioinformatics: Researchers develop a new machine learning approach
(via sciencedaily.com) Original source To combat viruses, bacteria and other pathogens, synthetic biology offers new technological approaches whose performance is being validated in experiments. Researchers applied data integration and artificial intelligence (AI) to develop a machine learning approach that can predict the efficacy of CRISPR technologies more accurately than before.
Published A novel pathway regulating lipid biosynthesis by fatty acids
(via sciencedaily.com) Original source Sterol regulatory element-binding proteins (SREBPs) play a crucial role in lipid biosynthesis. In a recent study, researchers identified a novel cleavage enzyme of SREBP-1c, a key player in fatty acid biosynthesis. Moreover, the team unveiled, for the first time, that the biosynthesis process of fatty acid in the liver is activated by saturated fatty acids and inhibited by polyunsaturated fatty acids, providing new insights into the intricate workings of this cleavage system.
Published New insights into what helps Salmonella cause infections
(via sciencedaily.com) Original source In a new study, researchers have discovered how a system of proteins, called TamAB, helps Salmonella survive under the harsh conditions inside macrophages.
Published Scientists uncover ocean's intricate web of microbial interactions across depths
(via sciencedaily.com) Original source An international team of scientists has uncovered the ocean's intricate web of microbial interactions across depths. Their research provides crucial insights into the functioning of ocean ecosystems.
Published 3D in vitro human atherosclerosis model for high-throughput drug screening
(via sciencedaily.com) Original source A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease, researchers report.
Published Researchers create light-powered yeast, providing insights into evolution, biofuels, cellular aging
(via sciencedaily.com) Original source Researchers have engineered one of the world's first yeast cells able to harness energy from light, expanding our understanding of the evolution of this trait -- and paving the way for advancements in biofuel production and cellular aging.
Published Spying on a shape-shifting protein
(via sciencedaily.com) Original source Researchers are using crystallography to gain a better understanding of how proteins shapeshift. The knowledge can provide valuable insight into stopping and treating diseases.
Published Study uncovers potential origins of life in ancient hot springs
(via sciencedaily.com) Original source A research team investigated how the emergence of the first living systems from inert geological materials happened on the Earth, more than 3.5 billion years ago. Scientists found that by mixing hydrogen, bicarbonate, and iron-rich magnetite under conditions mimicking relatively mild hydrothermal vent results in the formation of a spectrum of organic molecules, most notably including fatty acids stretching up to 18 carbon atoms in length.
Published Even the oldest eukaryote fossils show dazzling diversity and complexity
(via sciencedaily.com) Original source The sun has just set on a quiet mudflat in Australia's Northern Territory; it'll set again in another 19 hours. A young moon looms large over the desolate landscape. No animals scurry in the waning light. No leaves rustle in the breeze. No lichens encrust the exposed rock. The only hint of life is some scum in a few puddles and ponds. And among it lives a diverse microbial community of our ancient ancestors.
Published A global study reveals pathways to save threatened sharks, despite rising mortality trends
(via sciencedaily.com) Original source Sharks have persisted as powerful ocean predators for more than 400 million years. They survived five mass extinctions, diversifying into an amazing variety of forms and lifestyles. But this ancient lineage is now among the world's most threatened species groups due to overexploitation in poorly regulated fisheries and the proliferation of wasteful finning practices.
Published Lab-grown retinas explain why people see colors dogs can't
(via sciencedaily.com) Original source With human retinas grown in a petri dish, researchers discovered how an offshoot of vitamin A generates the specialized cells that enable people to see millions of colors, an ability that dogs, cats, and other mammals do not possess. The findings increase understanding of color blindness, age-related vision loss, and other diseases linked to photoreceptor cells. They also demonstrate how genes instruct the human retina to make specific color-sensing cells, a process scientists thought was controlled by thyroid hormones.
Published Protein complex discovered to control DNA repair
(via sciencedaily.com) Original source The repair of damage to genetic material (DNA) in the human body is carried out by highly efficient mechanisms that have not yet been fully researched. A scientific team has now discovered a previously unrecognized control point for these processes. This could lead to a new approach for the development of cancer therapies aimed at inhibiting the repair of damaged cancer cells.