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Categories: Biology: Molecular, Ecology: Sea Life

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New research reveals a chain of environmental disasters. These took place in what is today's South Africa, during an ancient time period called the Early-Middle Devonian. The crises led to the extinction of a unique group of marine animals called the Malvinoxhosan biota.

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Proteins are important molecules that perform a variety of functions essential to life. To function properly, many proteins must fold into specific structures. However, the way proteins fold into specific structures is still largely unknown. Researchers have developed a novel physical theory that can accurately predict how proteins fold. Their model can predict things previous models cannot. Improved knowledge of protein folding could offer huge benefits to medical research, as well as to various industrial processes.

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Yeast cells are widely used to study G protein-coupled receptors (GPCRs), a large group of cell surface proteins in humans. However, several of these proteins lose their function when introduced into yeast cells. To tackle this issue, researchers developed an innovative strategy to restore GPCR function in yeast cells by inducing random mutations. Their findings can help understand GPCRs better and could pave the way to therapeutic breakthroughs for many diseases.

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New soft, implantable fibers can deliver light to major nerves through the body. They are an experimental tool for scientists to explore the causes and potential treatments for peripheral nerve disorders in animal models.

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Many people have experienced a muddy off-flavor in farmed fish. While the aquaculture industry has known about the problem for 20 years, it continues to impact the consumption of otherwise healthy and potentially sustainable fish. Now, researchers have been able to pinpoint exactly when the off-flavors emerge. And this can make it easier to deal with the compounds that turn people away from farmed fish.

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Biodegradable plastics may not be the solution to plastic pollution many hoped for, with a new study showing they are still harmful to fish.

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A new study reveals how reduced water flows and rising atmospheric temperatures are set to heat our rivers -- creating major challenges for aquatic life, ecosystems, and society.

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A microscopic discovery will not only enable scientists to understand the microbial world around us but could also provide a new way to control CRISPR-Cas biotechnologies.

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The crown-of-thorns starfish is nature's ultimate coral predator that has a circle of life perfectly adapted to warming waters.

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The symbiotic communities of invertebrates in dead coral gravel on the shallow, warm-temperate coast of the Kii Peninsula in western Japan. New bivalve species and sideswimmer have been found to live communally with the greenish Bonellia spoonworm. Live-in symbionts share the burrows of other organisms in sand and mud on the seabed. However, studies on burrow niches in rigid substrates, such as rocks on the seabed, have been scarce.

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A research group has developed a new method for studying how cancer cells function in softer and stiffer tissue environments. This insight challenges the existing paradigm, opening up new possibilities for research in cancer biology and tissue engineering.

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A team has studied the mountainous star coral, Orbicella faveolata, to determine whether coral populations that have survived higher temperatures can pass their heat tolerance on to their offspring.  To the scientists' surprise, the results showed the opposite: The offspring from a population that is less heat-tolerant performed better when exposed to high temperatures than their counterparts from a heat-tolerant population. The findings counter the commonly held notion among scientists that if coral parents can handle the heat, so should their offspring. 

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Using cryo-electron microscopy (cryo-EM), researchers captured unprecedented images of key immune system receptors interacting with messenger proteins, elucidating how the receptors change shape upon activation and transmit signals within the cell. The findings suggest new pathways for developing therapeutic molecules for diseases such as COVID-19, rheumatoid arthritis, neurodegenerative diseases and cancer.

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Scientists measured microplastic concentrations in the highly productive Barents Sea and suggest that ocean circulation, ice melt, tourism, inadequate waste management, shipping and fishing are all likely contributors.

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Infections with cytomegalovirus (CMV) are extremely common and often pose no major threat to the vast majority of people. They can however be deadly for people whose immune system is weakened, e.g., after bone marrow transplantation. Current treatments against CMV infections are very limited and can have severe side effects. Researchers now propose a new way to protect against CMV. Instead of targeting the virus, their approach boosts the weak immune system and lets it fight the virus on its own.

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Researchers say they have found 'definitive' archaeological evidence that seaweeds and other local freshwater plants were eaten in the mesolithic, through the Neolithic transition to farming and into the Early Middle Ages, suggesting that these resources, now rarely eaten in Europe, only became marginal much more recently.

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The legendary Alexander Fleming, who famously discovered penicillin, once said 'never to neglect an extraordinary appearance or happening.' And the path of science often leads to just that. New research is turning the page in our understanding of harmful bacteria and how they turn on certain genes, causing disease in our bodies.

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Researchers have discovered how the fungus Candida albicans enters the brain, activates two separate mechanisms in brain cells that promote its clearance, and, important for the understanding of Alzheimer's disease development, generates amyloid beta (Ab)-like peptides, toxic protein fragments from the amyloid precursor protein that are considered to be at the center of the development of Alzheimer's disease.

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People overeat and become overweight for a variety of reasons. The fact that flavorful high-calorie food is often available nearly everywhere at any time doesn't help. Researchers have determined for the first time why certain chemicals in cooked or processed foods, called advanced glycation end products, or AGEs, increase hunger and test our willpower or ability to make healthy choices when it comes to food.

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Populations of charismatic animals have recovered since hunting ban but now struggle to find enough food.