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Categories: Biology: Biochemistry, Biology: Molecular
Published Machine learning method reveals chromosome locations in individual cell nucleus
(via sciencedaily.com) Original source Researchers have made a significant advancement toward understanding how the human genome is organized inside a single cell. This knowledge is crucial for analyzing how DNA structure influences gene expression and disease processes.
Published Bacteria in cancer unmasked
(via sciencedaily.com) Original source Researchers have compiled a detailed catalogue of bacteria living in cancer metastases. Having analyzed over 4000 tumors, they shed light on the diversity of these co-inhabitants and how they might interact with cancer cells and their surroundings. For example, certain bacteria were linked to a worse response to immunotherapy. This study paves the way to a better understanding of how bacteria help or hinder cancer (therapy), and how we can use this for patients' advantage.
Published Different means to the same end: How a worm protects its chromosomes
(via sciencedaily.com) Original source Researchers have discovered that a worm commonly used in the study of biology uses a set of proteins unlike those seen in other studied organisms to protect the ends of its DNA.
Published Scientists grow 'mini kidneys,' revealing new insights into metabolic defects and potential therapy for polycystic kidney disease
(via sciencedaily.com) Original source Scientists have successfully grown 'mini kidneys' in the lab and grafted them into live mice, revealing new insights into the metabolic defects and a potential therapy for polycystic kidney disease.
Published Toothed whale echolocation organs evolved from jaw muscles
(via sciencedaily.com) Original source Genetic analysis finds evidence suggesting that acoustic fat bodies in the heads of toothed whales were once the muscles and bone marrow of the jaw.
Published Bringing multidrug-resistant pathogens to their knees
(via sciencedaily.com) Original source Multidrug-resistant bacterial infections that cannot be treated by any known antibiotics pose a serious global threat. A research team has now introduced a method for the development of novel antibiotics to fight resistant pathogens. The drugs are based on protein building blocks with fluorous lipid chains.
Published How plants adjust their photosynthesis to changing light
(via sciencedaily.com) Original source Light supplies the energy plants need to build up biomass. A research team is researching how plants adapt their photosynthesis to changing light. They describe a key molecular mechanism that synchronizes the processes involved.
Published How mosquito larva guts could help create highly specific insecticides
(via sciencedaily.com) Original source Did you know that the world's deadliest animal is the mosquito? And Aedes aegypti is one of the most dangerous. This bug spreads viruses that cause dengue fever, which was recently declared as an epidemic in Puerto Rico. Research reports new molecules that label proteins in the unique, alkaline environment of the Ae. aegypti digestive system that could help scientists develop insecticides to fight back.
Published Mediterranean marine worm has developed enormous eyes
(via sciencedaily.com) Original source Scientists are amazed at the discovery of a bristle worm with such sharp-seeing eyes that they can measure up to those of mammals and octopuses. The researchers suspect that these marine worms may have a secretive language, which uses UV light only seen by their own species. The advanced vision of such a primitive creature helps to finally settle an epic debate about the evolution of eyes.
Published Integrated dataset enables genes-to-ecosystems research
(via sciencedaily.com) Original source A new dataset bridging molecular information about the poplar tree microbiome to ecosystem-level processes has been released. The project aims to inform research regarding how natural systems function, their vulnerability to a changing climate, and ultimately how plants might be engineered for better performance as sources of bioenergy and natural carbon storage.
Published In the evolution of walking, the hip bone connected to the rib bones
(via sciencedaily.com) Original source A new reconstruction of the 375-million-year-old fossil fish Tiktaalik -- a close relative of limbed vertebrates -- used micro-CT to reveal bones still embedded in matrix. The reconstruction shows that the fish's ribs likely attached to its pelvis, an innovation thought to be crucial to supporting the body and for the eventual evolution of walking.
Published Can language models read the genome? This one decoded mRNA to make better vaccines
(via sciencedaily.com) Original source Researchers developed a foundational language model to decode mRNA sequences and optimize those sequences for vaccine development. The tool shows broader promise as a means for studying molecular biology.
Published eDNA methods give a real-time look at coral reef health
(via sciencedaily.com) Original source The study underscores the crucial role of microbes in maintaining coral reef health, akin to the human gut microbiome. Hurricanes and disease outbreaks affect coral reef water microbial communities, leading to changes that may support further reef decline. Microbial analysis enables prompt assessment of disturbances' impacts on coral reefs, facilitating timely interventions to support reef ecosystems. Environmental DNA (eDNA) analysis offers a noninvasive approach to study coral microbial communities and diagnose reef health.
Published Heat stress from ocean warming harms octopus vision
(via sciencedaily.com) Original source While climate change has led to an increase in the abundance of octopuses, heat stress from projected ocean warming could impair their vision and impact the survivability of the species.
Published The life aquatic: A game changer for frog vision, but little difference between night and day
(via sciencedaily.com) Original source Frogs display a remarkable diversity of species as a whole, but does the same hold true for their visual abilities? A new study sought to answer this question by collaborating with researchers in Australia, Belgium, Brazil, Cameroon, Ecuador, Equatorial Guinea, French Guiana, Gabon, Seychelles, Sweden, United Kingdom and the United States, to get a sample of a diverse array of frogs to study the visual pigments found in their eyes. The researchers found this diversity is largely 'reflected' in the pigments, especially for aquatic frogs versus those living on the ground or in trees. They found little difference with the small groups of frogs that have adapted to daytime conditions as opposed to their nocturnal cousins.
Published Rusty-patched bumblebee's struggle for survival found in its genes
(via sciencedaily.com) Original source The rusty-patched bumblebee, once common in the United States, has declined from about 90% of its former range. Researchers conducted the first range-wide genetic study of the endangered species to inform recovery efforts.
Published Prairie voles display signs of human-like depression
(via sciencedaily.com) Original source Researchers make the case that prairie voles, small rodents that are found throughout the central United States and Canada, can be effectively used as animal models to further the study of clinical depression.
Published Shy sea anemones are more likely to survive heatwaves
(via sciencedaily.com) Original source A study shows that sea anemones that react more slowly to change can survive a heatwave better than individuals that change their behavior quickly.
Published New research offers insight into the future understanding of MS and its treatments
(via sciencedaily.com) Original source Researchers have developed a new and unique blood test to measure the immune response to the Epstein Barr Virus (EBV) which is the leading risk factor for developing multiple sclerosis (MS). Their findings have implications for future basic research in further understanding the biology of EBV in MS, but also has the potential to be applied in clinical trials that target the virus.
Published Heat flows the secret to order in prebiotic molecular kitchen
(via sciencedaily.com) Original source Biophysicists have demonstrated how heat flows through rock fissures could have created the conditions for the emergence of life.