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Categories: Biology: Biotechnology, Biology: Molecular

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A new biosensor offers scientists the first dynamic glimpses of manganese, an elusive metal ion that is essential for life.

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In the first step toward understanding how dogs -- and perhaps humans -- might adapt to intense environmental pressures such as exposure to radiation, heavy metals, or toxic chemicals, researchers found that two groups of dogs living within the Chernobyl Exclusion Zone showed significant genetic differences between them. The results indicate that these are two distinct populations that rarely interbreed. While earlier studies focused on the effects of the Chernobyl Nuclear Power Plant disaster on various species of wildlife, this is the first investigation into the genetic structure of stray dogs living near the Chernobyl nuclear power plant.

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Researchers have uncovered new evidence of western pygmy possums interacting with native flowers, providing an eDNA study to simultaneously detect mammal, insect and bird DNA on flowers.

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The DNA sequence of a gene in wheat responsible for resisting a devastating virus has been discovered, providing vital clues for managing more resistant crops and maintaining a healthy food supply.

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New methodology and tools provide an opportunity to watch in unprecedented detail as a phage attacks a bacterium.

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Obese fruit flies are the experimental subjects in a study of the causes of muscle function decline due to obesity. In humans, skeletal muscle plays a crucial role in metabolism, and muscle dysfunction due to human obesity can lead to insulin resistance and reduced energy levels.

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Once upon a time, prevailing scientific opinion might have pronounced recently published research as unneeded. Now, climate change implications have heightened the need for this line of research. Flowers emit scent chemicals called volatile organic compounds (VOCs). Earlier this year, a study identified a protein that plays a key role in helping petunias emit volatiles.

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An international team of bee researchers has integrated a calcium sensor into honey bees to enable the study of neural information processing including response to odors. This also provides insights into how social behavior is located in the brain.

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In early cytological studies chromatids of metaphase chromosomes were suggested to coil into a spiral called chromonema. This assumption was recently supported by chromosomce conformation capture sequencing. Still, the direct visualization of the coiled chromonema confirming the helical model was lacking. Now, an international research team provides the direct proof of the helical coiling of condensed chromatids via super-resolution microscopy of specifically labelled chromonema regions.

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Neuroscience research just got a little bit easier, thanks to the release of tens of thousands of images of fruit fly brain neurons.

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Scientists recently developed an efficient way to transplant pancreatic islets and demonstrated that the method can effectively reverse type 1 diabetes in nonhuman primates.

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Researchers have discovered a strong immunological effect of the molecule LecB -- and a way to prevent it.

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A major new study reveals a 'traffic light' mechanism controlling genetic activity within cells -- a system which could potentially be targeted by cancer drugs already in development. The research describes how 'epigenetic' changes to the structure of DNA can act as a stop-go signal in determining whether a gene should be read. Unlike our genetic make-up, which is well understood, the world of epigenetics is still largely unexplored and referred to as the 'dark matter' of the genome.

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A detailed atlas of gene expression in the zebrafish brain.

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Scientists thought a gold-throated hummingbird was a new species. DNA revealed that it's a hybrid of two different species, each with pink throats. The discovery sheds light on how birds produce feather colors and how hummingbirds evolved their dazzling hues.

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Researchers describe how gut-on-a-chip devices can bridge lab models and human biology. Modeling the microbiome is particularly difficult because of its unique environmental conditions, but through creative design, gut-on-a-chip devices can simulate many of these properties, such as the gut's anaerobic atmosphere, fluid flow, and pulses of contraction/relaxation. Growing intestinal cells in this environment means that they more closely resemble human biology compared to standard laboratory cell cultures.

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Biochemists have succeeded in resurrecting the ancestral genes of five detoxifying enzymes which are present in all tetrapods to show how their divergence in function has occurred.

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By simulating early Earth conditions in the lab, researchers have found that without specific amino acids, ancient proteins would not have known how to evolve into everything alive on the planet today -- including plants, animals, and humans.

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Textbooks will tell you that in dividing cells, production of new DNA peaks during the S-phase, while production of other macromolecules, such as proteins, lipids, and polysaccharides, continues at more or less the same level. Molecular biologists have now discovered that this is not true: protein synthesis shows two peaks and lipid synthesis peaks once.

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Haematopoietic stem cell transplantation for the treatment of severe blood cancers is the only medical intervention that has cured two people living with HIV in the past. An international group of physicians and researchers has now identified another case in which HIV infection has been shown to be cured in the same way. The successful healing process of this third patient was for the first time characterized in great detail virologically and immunologically over a time span of ten years.