Showing 20 articles starting at article 201

< Previous 20 articles        Next 20 articles >

Categories: Biology: Biotechnology, Biology: Molecular

Return to the site home page

     (via sciencedaily.com)     Original source 

Scientists used CRISPR/Cas9 to increase gene expression in rice by changing its upstream regulatory DNA. While other studies have used the technology to knock out or decrease the expression of genes, this study, is an unbiased gene-editing approach to increase gene expression and downstream photosynthetic activity. The approach is more difficult than transgenic breeding, but could potentially preempt regulatory issues by changing DNA already within the plant, allowing the plants to get in the hands of farmers sooner.

     (via sciencedaily.com)     Original source 

By studying mutations in yeast and human cells, scientists say they have found that biochemical bonds between fats and proteins in the mitochondrion, the cell's powerhouse, play a crucial role in how our cells produce energy.

     (via sciencedaily.com)     Original source 

Biomedical engineers have developed a silk-based, ultrathin membrane that can be used in organ-on-a-chip models to better mimic the natural environment of cells and tissues within the body. When used in a kidney organ-on-a-chip platform, the membrane helped tissues grow to recreate the functionality of both healthy and diseased kidneys.

     (via sciencedaily.com)     Original source 

What species live in this coral reef, and are they healthy? Chemical clues emitted by marine organisms might hold that information. But in underwater environments, invisible compounds create a complex 'soup' that is hard for scientists to decipher. Now, researchers have demonstrated a way to extract and identify these indicator compounds in seawater. They found metabolites previously undetected on reefs, including three that may represent different reef organisms.

     (via sciencedaily.com)     Original source 

Researchers have been investigating the molecular mechanisms responsible for determining sex in ants. Although the vast majority of an ant colony consists of female workers, males are essential to the continuing survival of the species. In order to uncover the mechanisms involved, the researchers decided to focus on diploid males, which occasionally occur in the Argentine ant.

     (via sciencedaily.com)     Original source 

Researchers provide the first insight into the mode of action of the lipopeptide serrawettin W2-FL10, derived from Serratia marcescens. This lipopeptide targets the cell membrane of S. aureus, causing lesions which result in the leakage of intracellular components and ultimately cell death.

     (via sciencedaily.com)     Original source 

The swirl of milk and espresso -- a small storm in your mug -- doesn't impact the dynamics of the milk proteins, according to research. Researchers took a molecular view of how milk proteins and caffeine molecules interact in water and in a coffee drink. The results suggest that the structures of milk proteins remain intact, meaning they retain their original mouthfeel and taste in your morning brew.

     (via sciencedaily.com)     Original source 

Around 100 million years ago, a remarkable evolutionary shift allowed placental mammals to diversify and conquer many cold regions of our planet. New research shows that the typical mammalian heater organ, brown fat, evolved exclusively in modern placental mammals. The research team demonstrated that marsupials, our distant relatives, possess a not fully evolved form of brown fat. They discovered that the pivotal heat-producing protein called UCP1 became active after the divergence of placental and marsupial mammals. This finding is crucial for understanding the role of brown fat in mammalian evolution, endothermy, and metabolism.

     (via sciencedaily.com)     Original source 

Strong bitterness is the main reason why people all over the world, especially children, avoid taking their medicines, putting their health, and sometimes, their lives at risk. Now, a group of scientists has identified the first temporary, universal taste blocker that works in people.

     (via sciencedaily.com)     Original source 

A new study suggests that adding common bone loss drugs to azoles can improve efficacy when treating fungal infections.

     (via sciencedaily.com)     Original source 

Researchers invented a technique that allows them to observe which genes and enhancers are active in a cell at the same time. This could help them determine which enhancers control which genes and may reveal potential new drug targets for genetic disorders.

     (via sciencedaily.com)     Original source 

A recent study provides new insights into how fathers' diets and overweight can affect their children's health even before conception. The findings of the study can help develop preventive health measures for men wishing to become fathers: The healthier the father's diet, the lower the risk for their children to develop obesity or diseases such as diabetes later in life.

     (via sciencedaily.com)     Original source 

Maternal obesity impacts the eating behaviors of offspring via long-term overexpression of the microRNA miR-505-5p, according to a new study.

     (via sciencedaily.com)     Original source 

Giant viruses found on the Greenland ice sheet probably regulate the growth of snow algae on the ice by infecting them. Knowing how to control these viruses could help us reduce the rate of ice-melt.

     (via sciencedaily.com)     Original source 

Biological processes depend on puzzle pieces coming together and interacting. Under specific conditions, these interactions can create something new without external input. This is called self-organization, as seen in a school of fish or a flock of birds. Interestingly, the mammalian embryo develops similarly. Scientists now introduce a mathematical framework that analyzes self-organization from a single cell to a multicellular organism.

     (via sciencedaily.com)     Original source 

Under certain conditions, some algae are able to produce hydrogen -- a much sought-after green energy source. Its production takes place in the unique catalytic center of the unicellular algae and is only possible if certain cofactors of the relevant proteins are present. Researchers have identified how such a cofactor, the so-called hydrogen cluster, is assembled. Specifically, they describe the previously unexplained role of the enzyme HydF, which is involved in the final steps of assembly.

     (via sciencedaily.com)     Original source 

An international team has found a new RNA virus that they believe is hitching a ride with a common human parasite. The virus is associated with severe inflammation in humans infected with the parasite Toxoplasma gondii, leading the team to hypothesize that it exacerbates toxoplasmosis disease.

     (via sciencedaily.com)     Original source 

Scientists have discovered that the most widely-used class of antifungals in the world cause pathogens to self-destruct. The research could help improve ways to protect food security and human lives.

     (via sciencedaily.com)     Original source 

Trout living in rivers polluted by metal from old mines across the British Isles are genetically 'isolated' from other trout, new research shows.

     (via sciencedaily.com)     Original source 

Researchers have developed a novel version of a key CRISPR gene-editing protein that shows efficient editing activity and is small enough to be packaged within a non-pathogenic virus that can deliver it to target cells.