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Categories: Biology: Biotechnology, Biology: Molecular
Published Calorie restriction study reveals complexities in how diet impacts aging
(via sciencedaily.com) Original source The rate at which human cells age is influenced by multiple interconnected factors. New research examined how restricting calories influences telomere length and biological aging.
Published Solving a mini mystery of cell division
(via sciencedaily.com) Original source Trying to hit a target size before dividing seems like the best strategy for maintaining a precise cell size, but bacteria don't do that. Now we know why.
Published Plant sensors could act as an early warning system for farmers
(via sciencedaily.com) Original source Using a pair of sensors made from carbon nanotubes, researchers discovered signals that help plants respond to stresses such as heat, light, or attack from insects or bacteria. Farmers could use these sensors to monitor threats to their crops, allowing them to intervene before the crops are lost.
Published Tracking a protein's fleeting shape changes
(via sciencedaily.com) Original source Researchers have developed a powerful, new technique to generate 'movies' of changing protein structures and speeds of up to 50 frames per second.
Published Researchers uncover human DNA repair by nuclear metamorphosis
(via sciencedaily.com) Original source Researchers have discovered a DNA repair mechanism that advances understanding of how human cells stay healthy, and which could lead to new treatments for cancer and premature aging.
Published Older males out-compete young males outside breeding pairs, bird study shows
(via sciencedaily.com) Original source Young male blue tits are less successful in fathering offspring outside their breeding pair, not because of a lack of experience, but because they are outcompeted by older males, researchers report.
Published How tardigrades can survive intense radiation
(via sciencedaily.com) Original source Researchers have discovered that tardigrades -- microscopic animals famed for surviving harsh extremes -- have an unusual response to radiation.
Published How blue-green algae manipulate microorganisms
(via sciencedaily.com) Original source A research team discovers previously unknown gene that indirectly promotes photosynthesis Protein regulator NirP1 influences the coordination of the nitrogen and carbohydrate metabolism 'Such protein regulators could in future be deployed in 'green' and 'blue' biotechnology for targeted control of the metabolism,' says geneticist.
Published Unlocking the 'chain of worms'
(via sciencedaily.com) Original source An international team of scientists has published a single-cell atlas for Pristina leidyi (Pristina), the water nymph worm, a segmented annelid with extraordinary regenerative abilities that has fascinated biologists for more than a century.
Published Millions of gamers advance biomedical research
(via sciencedaily.com) Original source 4.5 million gamers around the world have advanced medical science by helping to reconstruct microbial evolutionary histories using a minigame included inside the critically and commercially successful video game, Borderlands 3. Their playing has led to a significantly refined estimate of the relationships of microbes in the human gut. The results of this collaboration will both substantially advance our knowledge of the microbiome and improve on the AI programs that will be used to carry out this work in future.
Published Researchers resolve old mystery of how phages disarm pathogenic bacteria
(via sciencedaily.com) Original source Bacterial infections pose significant challenges to agriculture and medicine, especially as cases of antibiotic-resistant bacteria continue to rise. In response, scientists are elucidating the ways that bacteria-infecting viruses disarm these pathogens and ushering in the possibility of novel treatment methods.
Published Starving cells hijack protein transport stations
(via sciencedaily.com) Original source Study details how nutrient-starved cells divert protein transport stations to cellular recycling centers to be broken down, highlighting a novel approach cells use to deal with stressful conditions.
Published Cell's 'garbage disposal' may have another role: Helping neurons near skin sense the environment
(via sciencedaily.com) Original source The typical job of the proteasome, the garbage disposal of the cell, is to grind down proteins into smaller bits and recycle some of those bits and parts. That's still the case, for the most part, but researchers, studying nerve cells grown in the lab and mice, say that the proteasome's role may go well beyond that.
Published How seaweed became multicellular
(via sciencedaily.com) Original source A deep dive into macroalgae genetics has uncovered the genetic underpinnings that enabled macroalgae, or 'seaweed,' to evolve multicellularity. Three lineages of macroalgae developed multicellularity independently and during very different time periods by acquiring genes that enable cell adhesion, extracellular matrix formation, and cell differentiation, researchers report. Surprisingly, many of these multicellular-enabling genes had viral origins. The study, which increased the total number of sequenced macroalgal genomes from 14 to 124, is the first to investigate macroalgal evolution through the lens of genomics.
Published Microbial food as a strategy food production of the future
(via sciencedaily.com) Original source Scientists have summarized microbial food production strategies.
Published Decoding the language of cells: Unveiling the proteins behind cellular organelle communication
(via sciencedaily.com) Original source A collaboration unveils a novel strategy for identifying key proteins in organelle communication. This approach advances our ability to pinpoint proteins essential for organelle interactions within specific spatial and temporal contexts.
Published Innovative antiviral defense with new CRISPR tool
(via sciencedaily.com) Original source The rise of RNA viruses like SARS-CoV-2 highlights the need for new ways to fight them. RNA-targeting tools like CRISPR/Cas13 are powerful but inefficient in the cytoplasm of cells, where many RNA viruses replicate. Scientists have devised a solution: Cas13d-NCS. This new molecular tool allows CRISPR RNA molecules that are located within the nucleus of a cell to move to the cytoplasm, making it highly effective at neutralizing RNA viruses. This advancement opens doors for precision medicine and proactive viral defense strategies.
Published First step to untangle DNA: Supercoiled DNA captures gyrase like a lasso ropes cattle
(via sciencedaily.com) Original source Researchers reveal how DNA gyrase resolves DNA entanglements. The findings not only provide novel insights into this fundamental biological mechanism but also have potential practical applications. Gyrases are biomedical targets for the treatment of bacterial infections and the similar human versions of the enzymes are targets for many anti-cancer drugs. Better understanding of how gyrases work at the molecular level can potentially improve clinical treatments.
Published Brainless memory makes the spinal cord smarter than previously thought
(via sciencedaily.com) Original source Researchers have discovered the neural circuitry in the spinal cord that allows brain-independent motor learning. The study found two critical groups of spinal cord neurons, one necessary for new adaptive learning, and another for recalling adaptations once they have been learned. The findings could help scientists develop ways to assist motor recovery after spinal cord injury.
Published New approach for combating 'resting' bacteria
(via sciencedaily.com) Original source Most disease-causing bacteria are known for their speed: In mere minutes, they can double their population, quickly making a person sick. But just as dangerous as this rapid growth can be a bacterium's resting state, which helps the pathogen evade antibiotics and contributes to severe chronic infections in the lungs and blood, within wounds, and on the surfaces of medical devices. Now, scientists have discovered how long chains of molecules called polyphosphates (polyP) are needed for bacteria to slow down movements within cells and let them enter this resting state.