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Categories: Biology: Biotechnology, Biology: Molecular
Published Shedding new light on sugars, the 'dark matter' of cellular biology
(via sciencedaily.com) Original source Chemists have developed a new tool for detecting interactions between sugars and lectins, a discovery that could help in the fight against diseases like cancer.
Published A tale of two proteins: Fundamental research could make growing better crops like clockwork
(via sciencedaily.com) Original source Rhomboid-like protein 10, or RBL10, is thought to be an enzyme that degrades other proteins in the chloroplast membrane, but its function is largely unknown. Researchers are studying how RBL10 affects photosynthetic membrane lipid metabolism, an essential process in photosynthesis.
Published New discovery on how green algae count cell divisions illuminates key step needed for the evolution of multicellular life
(via sciencedaily.com) Original source An international research team has made an unexpected discovery of a biased counting mechanism used by the single-celled green alga Chlamydomonas to control cell division.
Published How marine bristle worms use a special protein to distinguish between sunlight and moonlight
(via sciencedaily.com) Original source A research team has presented its findings on the functioning of an atypical cryptochrome protein (Cry). These proteins are found in a variety of organisms, and they are often involved in light-controlled biological processes. The marine bristle worm Platynereis dumerilii, for example, employs a special Cry protein designated L-Cry to distinguish between sunlight and moonlight as well as between different moon phases. This is essential for the worms to synchronize their reproduction to the full moon phase via an inner monthly calendar, also called circalunar clock.
Published Ground-breaking discovery could pave the way for new therapies to prevent cardiovascular disease and stroke
(via sciencedaily.com) Original source Researchers have discovered the mechanism by which cholesterol in our diet is absorbed into our cells. This discovery opens up new opportunities for therapeutic intervention to control cholesterol uptake that could complement other therapies and potentially save lives.
Published The Goldilocks Effect: Researchers establish framework for protein regulation
(via sciencedaily.com) Original source Researchers are working to understand how protein quality control works in cells.
Published New drug-like molecule extends lifespan, ameliorates pathology in worms and boosts function in mammalian muscle cells
(via sciencedaily.com) Original source Having healthy mitochondria, the organelles that produce energy in all our cells, usually portends a long healthy life whether in humans or in C. elegans, a tiny, short-lived nematode worm often used to study the aging process. Researchers have identified a new drug-like molecule that keeps mitochondria healthy via mitophagy, a process that removes and recycles damaged mitochondria in multicellular organisms. The compound, dubbed MIC, is a natural compound that extended lifespan in C. elegans, ameliorated pathology in neurodegenerative disease models of C. elegans, and improved mitochondrial function in mouse muscle cells.
Published New work sheds light on inner working of cells
(via sciencedaily.com) Original source New research provides a deeper understanding of the way components within cells are interconnected. Through cellular visualization using SRS microscopy, researchers have addressed the challenge of attaining clear images of individual processes.
Published The mystery of phosphite -- a scientific detective story
(via sciencedaily.com) Original source Biologists have discovered a phosphorus-based bacterial metabolism that is both new and ancient. In a special role: a calculation from the 1980s, a sewage plant, a new bacterial organism, and a remnant from around 2.5 billion years ago.
Published Yeast cells can produce drugs for treatment of psychotic disorders
(via sciencedaily.com) Original source An international team of researchers has demonstrated that genetically engineered yeast cells can produce the natural plant product alstonine, which has shown positive effects in treating schizophrenia.
Published Team creates synthetic enzymes to unravel molecular mysteries
(via sciencedaily.com) Original source A bioengineer has developed synthetic enzymes that can control the behavior of the signaling protein Vg1, which plays a key role in the development of muscle, bone and blood in vertebrate embryos. The team of researchers is using a new approach, called the Synthetic Processing (SynPro) system, in zebrafish to study how Vg1 is formed. By learning the molecular rules of signal formation in a developing animal, researchers aim to engineer mechanisms -- such as giving cells new instructions -- that could play a role in treating or preventing disease.
Published New way to count microbes speeds research, cuts waste, could lead to new antibiotics
(via sciencedaily.com) Original source Researchers have developed a new way of counting microorganisms that works as much as 36 times faster than conventional methods, cuts plastic use more than 15-fold and substantially decreases the cost and carbon footprint of biomedical research. The technique could revolutionize the way microbiology experiments are conducted, allowing researchers to test potential new antibiotics in a fraction of the time.
Published Scientists use quantum biology, AI to sharpen genome editing tool
(via sciencedaily.com) Original source Scientists used their expertise in quantum biology, artificial intelligence and bioengineering to improve how CRISPR Cas9 genome editing tools work on organisms like microbes that can be modified to produce renewable fuels and chemicals.
Published A breath of fresh air keeps drug-producing cells alive longer
(via sciencedaily.com) Original source Researchers have developed a novel device that produces oxygen inside of a 'living pharmacy' implant in order to keep cells alive inside the self-contained device. The device produses oxygen through a smart, energy-efficient version of water splitting. In new experiments, the novel device kept cells (70-80%) alive for close to a month in low oxygen conditions in vitro, or weeks in vivo.
Published First live birth of a chimeric monkey using embryonic stem cell lines
(via sciencedaily.com) Original source A team of researchers has reported for the first time the live birth of a monkey that contains a high proportion of cells derived from a monkey stem cell line. This 'chimeric' monkey is composed of cells that originate from two genetically distinct embryos of the same species of monkey. This has previously been demonstrated in rats and mice but, until now, has not been possible in other species, including non-human primates.
Published Zen and the art of mitochondrial maintenance: The machinery of death makes a healthier life
(via sciencedaily.com) Original source While we all aspire for a long lifespan, what is most coveted is a long period of vigor and health, or 'healthspan,' that precedes the inevitable decline of advancing age. Researchers have discovered that instruments of death that cells use to commit suicide when things go wrong contribute to making a longer and healthier life by revitalizing the specialized cellular compartments called mitochondria.
Published Temperature increase triggers viral infection
(via sciencedaily.com) Original source Researchers have mapped on an atomic level what happens in a virus particle when the temperature is raised.
Published How animals get their stripes and spots
(via sciencedaily.com) Original source New research helps explain how sharp patterns form on zebras, leopards, tropical fish and other creatures. Their findings could inform the development of new high-tech materials and drugs.
Published Head lice evolution mirrors human migration and colonization in the Americas
(via sciencedaily.com) Original source A new analysis of lice genetic diversity suggests that lice came to the Americas twice -- once during the first wave of human migration across the Bering Strait, and again during European colonization.
Published Identifying a silicon transporter to improve the yield of rice
(via sciencedaily.com) Original source Researchers identify a membrane transporter in rice that regulates the accumulation and localization of silicon in the leaves.