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Categories: Biology: Biotechnology, Biology: Molecular
Published The 'treadmill conveyor belt' ensuring proper cell division



Researchers have discovered how proteins work in tandem to regulate 'treadmilling', a mechanism used by the network of microtubules inside cells to ensure proper cell division.
Published Researchers target lifecycle of parasite behind Chagas disease



Researchers are studying the signaling pathway that leads the parasite responsible for Chagas disease to transform and reproduce. They follow that pathway from the beginning when an uninfected kissing bug acquires the parasite by biting an infected mammal host all the way to the time the parasite develops in the insect's gut to be spread to people or animals through the bug's poop.
Published Longevity gene from naked mole rats extends lifespan of mice



In a groundbreaking endeavor, researchers have successfully transferred a longevity gene from naked mole rats to mice, resulting in improved health and an extension of the mouse's lifespan. The research opens exciting possibilities for unlocking the secrets of aging and extending human lifespan.
Published Researchers unearth a new process by which algae pass on nurtrients to their coral host


Researchers have identified a new pathway by which sugar is released by symbiotic algae. This pathway involves the largely overlooked cell wall, showing that this structure not only protects the cell but plays an important role in symbiosis and carbon circulation in the ocean.
Published Biologist gets the scoop on squash bug poop



A discovery about how a common insect acquires a microbe that is essential for its growth may help in the control of an agricultural pest.
Published Noncoding DNA explains a majority of the heritability of dairy cattle traits, like milk production and fertility



Regulatory genes -- genes that control how other genes are used -- are responsible for 69% of the heritability of dairy cattle traits such as milk production and fertility, according to a new study. This contribution is 44% more than expected and much higher than previous studies of regulatory genes in humans. The findings, reported by a team of animal and human geneticists, could improve the efficiency of agricultural breeding programs. The study also helps solve the longstanding mystery of why mammalian genomes contain so much noncoding DNA.
Published High-fat diets alter gut bacteria, boosting colorectal cancer risk in mice



Researchers have discovered how high-fat diets can change gut bacteria and alter digestive molecules called bile acids that are modified by those bacteria, predisposing mice to colorectal cancer. The findings bring scientists closer to understanding the causes of and how to prevent colorectal cancer.
Published Research team developing a nano-sized force sensor and improving high-precision microscopy technology


Recent research in cell biology highlights groundbreaking results. An international team of researchers have recently established a tool they developed to study the mechanics of the cell. The tool can be used to study the inner forces of the cell, for example, the stretching of the nuclear membrane. The microscopic force sensor, only about 0.00002 mm long, is constructed of exotic ingredients such as spider web protein parts, fluorescent proteins from jellyfish, and antibodies from alpaca. In addition, the multidisciplinary team of researchers has developed further the sensitivity of super-resolution microscopy technique.
Published 'Viral relicts' in the genome could fuel neurodegeneration



Genetic remnants of viruses that are naturally present in the human genome could affect the development of neurodegenerative diseases. Researchers come to this conclusion on the basis of studies on cell cultures.
Published Ancient metal cauldrons give us clues about what people ate in the Bronze Age



Archaeologists have long been drawing conclusions about how ancient tools were used by the people who crafted them based on written records and context clues. But with dietary practices, they have had to make assumptions about what was eaten and how it was prepared. A new study analyzed protein residues from ancient cooking cauldrons and found that the people of Caucasus ate deer, sheep, goats, and members of the cow family during the Maykop period (3700--2900 BCE).
Published Increasing legumes and reducing red meat is safe for bone health and protein intake



A study has demonstrated that the partial substitution of red and processed meat with pea- and faba bean -- based food products ensured sufficient intake of amino acids in the diet and did not negatively affect bone metabolism.
Published Scientists reveal how sensory protein changes shape with nanometer resolution


The sensory receptor PIEZO1 changes shape in response to mechanical stimuli. The super high-resolution microscopy technology used in this discovery is a breakthrough in enabling protein structures to be studied within the cellular environment.
Published Researchers develop digital test to directly measure HIV viral load



A milliliter of blood contains about 15 individual drops. For a person with human immunodeficiency virus (HIV), each drop of blood could contain anywhere from fewer than 20 copies of the virus to more than 500,000 copies. Called the viral load, this is what is measured to allow clinicians to understand how patients are responding to anti-viral medications and monitor potential progression. The time-consuming viral load testing needs to be repeated several times as a patient undergoes treatment. Now, a research team has developed a time and cost-efficient digital assay that can directly measure the presence of HIV in single drop of blood.
Published Extinct warbler's genome sequenced from museum specimens



The Bachman's warbler, a songbird that was last seen in North America nearly 40 years ago, was a distinct species and not a hybrid of its two living sister species, according a new study in which the full genomes of seven museum specimens of the bird were sequenced.
Published Drug decelerates bacterial race to antibiotic resistance



Researchers report that, in laboratory cultures and animal models, a drug significantly reduces the ability of bacteria to develop antibiotic resistance, which might prolong antibiotic effectiveness.
Published Researcher uses pressure to understand RNA dynamics



Just as space holds infinite mysteries, when we zoom in at the level of biomolecules (one trillion times smaller than a meter), there is still so much to learn. Scientists are studying the conformational landscapes of biomolecules and how they modulate cell function. When biomolecules receive certain inputs, it can cause the atoms to rearrange and the biomolecule to change shape. This change in shape affects their function in cells, so understanding conformational dynamics is critical for drug development.
Published The molecular control center of our protein factories



Researchers have deciphered a biochemical mechanism that ensures that newly formed proteins are processed correctly when they leave the cell's own protein factories. This solves a decade-old puzzle in protein sorting.
Published The clue is in the glue -- Nature's secret for holding it together



An obscure aquatic plant has helped to explain how plants avoid cracking up under the stresses and strains of growth.
Published Studying herpes encephalitis with mini-brains



The herpes simplex virus-1 can sometimes cause a dangerous brain infection. Combining an anti-inflammatory and an antiviral could help in these cases, report scientists.
Published Unraveling the connections between the brain and gut



Engineers designed a technology to probe connections between the brain and the digestive tract. Using fibers embedded with a variety of sensors, as well as optogenetic stimulation, the researchers could control neural circuits connecting the gut and the brain, in mice.