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Categories: Biology: Cell Biology, Biology: Molecular
Published Minimalist or maximalist? The life of a microbe a mile underground



Researchers characterize nearly 600 microbial genomes collected from goldmine. The study illuminates 'microbial dark matter' residing below the surface. Microbes divide into two groups: minimalists that have one, specialized job or maximalists that are prepared to use any available resource. Study has implications for how underground activities, like mining and carbon storage, could affect or be affected by microbial life. The lifestyle of these 'intraterrestrial' microbes also provides hints to what organisms could be living on other planets.
Published Scientist discovers potential brain link between stress, emotional eating



Scientists describe how they identified a molecule that may trigger over-consumption of comfort foods after a threatening event.
Published Fish IgM structure sheds light on antibody evolution



Researchers have analyzed the antibody Immunoglobulin M in rainbow trout to shed some light on why these proteins may have evolved over time.
Published Study provides fresh insights into antibiotic resistance, fitness landscapes



A new study suggests that E. coli bacteria may have a higher capability to evolve antibiotic resistance than previously believed. Researchers mapped possible mutations in an essential E. coli protein involved in antibiotic resistance and found that 75% of evolutionary paths led to high antibiotic resistance, challenging existing theories about fitness landscapes in evolutionary biology. This discovery may have broader implications for understanding adaptation and evolution in various fields.
Published New clues into the head-scratching mystery of itch



Scientists show for the first time that bacteria can cause itch by activating nerve cells in the skin. The findings can inform new therapies to treat itch that occurs in inflammatory skin conditions like eczema and dermatitis.
Published Hybrid transistors set stage for integration of biology and microelectronics



Researchers create transistors combining silicon with biological silk, using common microprocessor manufacturing methods. The silk protein can be easily modified with other chemical and biological molecules to change its properties, leading to circuits that respond to biology and the environment.
Published Nutrient found in beef and dairy improves immune response to cancer



Trans-vaccenic acid (TVA), a long-chain fatty acid found in meat and dairy products from grazing animals such as cows and sheep, improves the ability of CD8+ T cells to infiltrate tumors and kill cancer cells, according to a new study.
Published Researchers puncture 100-year-old theory of odd little 'water balloons'



Quinoa and many other extremely resilient plants are covered with strange balloon-like 'bladders' that for 127 years were believed to be responsible for protecting them from drought and salt. Research results reveal this not to be the case. These so-called bladder cells serve a completely different though important function. The finding makes it likely that even more resilient quinoa plants will now be able to be bred, which could lead to the much wider cultivation of this sustainable crop worldwide.
Published Team discovers rules for breaking into Pseudomonas



Researchers report that they have found a way to get antibacterial drugs through the nearly impenetrable outer membrane of Pseudomonas aeruginosa, a bacterium that -- once it infects a person -- is notoriously difficult to treat.
Published Tiny beads preserve enzymes for biocatalysis



Some enzymes, such as the one derived from fungi and investigated in this study, are able to produce valuable substances such as the fragrance (R)-1-phenylethanol. To this end, they convert a less expensive substrate using a co-substrate. A research team came up with the idea of supplying them with this co-substrate using a plasma -- a somewhat crazy idea, as plasmas generally have a destructive effect on biomolecules. However, by employing several tricks, the researchers did indeed succeed. They have now refined one of these tricks and thus improved the process: They attach the enzymes to tiny beads in order to hold them in place at the bottom of the reactor, where they are protected from the damaging effects of the plasma.
Published Looking for 'LUCA' and the timing of cellular evolution



LUCA, the 'last universal common ancestor' of all living organisms, lived 4.32 to at most 4.52 billion years ago. What LUCA looked like is unknown, but it must have been a cell with among others ribosomal proteins and an ATP synthase.
Published Laser-powered 'tweezers' reveal universal mechanism viruses use to package up DNA



Researchers have used laser-powered ‘optical tweezers’ to reveal a universal motor mechanism used by viruses for packaging their DNA into infectious particles.
Published Researchers shed light on how one deadly pathogen makes its chemicals



Investigators have played a key role in deciphering a previously unidentified cluster of genes responsible for producing sartorypyrones, a chemical made by the fungal pathogen Aspergillus fumigatus, whose family causes Aspergillosis in humans.
Published How gut microbes help alleviate constipation



Scientists have identified the genes in the probiotic Bifidobacteria longum responsible for improving gut motility. A research team found that B. longum strains possessing the abfA cluster of genes can ameliorate constipation through enhanced utilization of an indigestible fiber called arabinan in the gut.
Published Unearthing how a carnivorous fungus traps and digests worms



A new analysis sheds light on the molecular processes involved when a carnivorous species of fungus known as Arthrobotrys oligospora senses, traps and consumes a worm.
Published Bacteria store memories and pass them on for generations



Scientists have discovered that bacteria can create something like memories about when to form strategies that can cause dangerous infections in people, such as resistance to antibiotics and bacterial swarms when millions of bacteria come together on a single surface. The discovery -- which has potential applications for preventing and combatting bacterial infections and addressing antibiotic-resistant bacteria -- relates to a common chemical element bacterial cells can use to form and pass along these memories to their progeny over later generations.
Published Coffee grounds may hold key to preventing neurodegenerative diseases



A team of researchers found that caffeic-acid based Carbon Quantum Dots (CACQDs), which can be derived from spent coffee grounds, have the potential to protect brain cells from the damage caused by several neurodegenerative diseases.
Published Innovative aquaculture system turns waste wood into nutritious seafood



Innovative aquaculture system turns waste wood into nutritious seafood. Researchers hoping to rebrand a marine pest as a nutritious food have developed the world's first system of farming shipworms, which they have renamed 'Naked Clams'.
Published New computer code for mechanics of tissues and cells in three dimensions



Biological materials are made of individual components, including tiny motors that convert fuel into motion. This creates patterns of movement, and the material shapes itself with coherent flows by constant consumption of energy. Such continuously driven materials are called 'active matter'. The mechanics of cells and tissues can be described by active matter theory, a scientific framework to understand shape, flows, and form of living materials. The active matter theory consists of many challenging mathematical equations. Scientists have now developed an algorithm, implemented in an open-source supercomputer code, that can for the first time solve the equations of active matter theory in realistic scenarios. These solutions bring us a big step closer to solving the century-old riddle of how cells and tissues attain their shape and to designing artificial biological machines.
Published Researchers develop comprehensive genetic map for bison, discover gene responsible for albinism



Researchers have determined the gene mutation responsible for an observable trait in bison -- albinism.