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Categories: Biology: Cell Biology, Biology: Molecular
Published Mammalian evolution provides hints for understanding the origins of human disease
(via sciencedaily.com) Original source Even though it is important to know where these variations are located in the genome, it's also useful to know how or why these genetic variations happened in the first place.
Published How dormant bacteria come back to life
(via sciencedaily.com) Original source Bacterial spores can survive for years, even centuries, without nutrients, resisting heat, UV radiation, and antibiotics. How inert, sleeping bacteria -- or spores -- spring back to life has been a century-long mystery. New research identifies how sensor proteins revive dormant bacteria. Discovery opens new routes to combat spore resistance to antibiotics and sterilization. Findings can inform novel strategies to prevent infections, food spoilage.
Published Scientists discover antibiotic resistance genes in clouds
(via sciencedaily.com) Original source The atmosphere is a large-scale dissemination route for bacteria carrying antibiotic-resistance genes. A research team has shown that these genes can be transported by clouds.
Published Maths unlocks molecular interactions that open window to how life evolved
(via sciencedaily.com) Original source Landmark research by mathematicians sets out the definitive picture of biological adaptation at the level of intermolecular interactions.
Published New findings indicate gene-edited rice might survive in Martian soil
(via sciencedaily.com) Original source New research suggests future Martian botanists may be able to grow gene-edited rice on Mars.
Published Brain circuits for locomotion evolved long before appendages and skeletons
(via sciencedaily.com) Original source Scientists found parallels between the neural circuitry that guides locomotion in sea slugs and in more complex animals like mammals.
Published Near-universal T cell immunity towards a broad range of bacteria
(via sciencedaily.com) Original source Typically T cells of the immune system respond to a specific feature (antigen) of a microbe, thereby generating protective immunity. Scientists have discovered an exception to this rule. Namely, a group of divergent bacterial pathogens, including pneumococci, all share a small highly conserved protein sequence, which is both presented and recognized by human T cells in a conserved population-wide manner.
Published Ocean ecosystem: Mixotrophic microorganisms play key role
(via sciencedaily.com) Original source Researchers have identified a previously unknown group of bacteria, called UBA868, as key players in the energy cycle of the deep ocean. They are significantly involved in the biogeochemical cycle in the marine layer between 200 and 1000 meters.
Published Luring the virus into a trap
(via sciencedaily.com) Original source Viruses like influenza A and Ebola invade human cells in a number of steps. Research teams investigated the final stages of viral penetration using electron tomography and computer simulations. So-called fusion pores, through which the viral genome is released into the host cell, play a central role in these processes. If they can be prevented from forming, the virus is also blocked. The Heidelberg scientists describe previously unknown mechanisms, which might lead to new approaches to prevent infections.
Published Researchers reveal an ancient mechanism for wound repair
(via sciencedaily.com) Original source The study is the first to identify a damage response pathway that is distinct from but parallel to the classical pathway triggered by pathogens.
Published 'BeerBots' could speed up the brewing process
(via sciencedaily.com) Original source Craft brewers are continuously upping the ante and coming up with innovative ways to make or flavor their newest beers. Now, researchers are adding a new twist of their own, speeding up the brewing process with beer-making mini-robots or 'BeerBots.' The team shows that these self-propelled, magnetic packages of yeast can make the fermentation phase go faster and cut out the need to filter the beverage.
Published This gel stops brain tumors in mice. Could it offer hope for humans?
(via sciencedaily.com) Original source Medication delivered by a novel gel cured 100% of mice with an aggressive brain cancer, a striking result that offers new hope for patients diagnosed with glioblastoma, one of the deadliest and most common brain tumors in humans.
Published Testing antibiotic resistance with a fast, cheap, and easy method
(via sciencedaily.com) Original source Researchers have developed a novel and highly efficient method for rapid antibiotic susceptibility testing using optical microscopy. The technique, called Optical Nanomotion Detection, is extremely rapid, single-cell sensitive, label-free, and requires only a basic traditional optical microscope, equipped with a camera or a mobile phone.
Published New biologic effective against major infection in early tests
(via sciencedaily.com) Original source A research team has shown in early tests that a bioengineered drug candidate can counter infection with Staphylococcus aureus -- a bacterial species widely resistant to antibiotics.
Published Algae in Swedish lakes provide insights to how complex life on Earth developed
(via sciencedaily.com) Original source By studying green algae in Swedish lakes, a research team has succeeded in identifying which environmental conditions promote multicellularity. The results give us new clues to the amazing paths of evolution.
Published Researchers reveal a map to study novel form of cell-to-cell communication
(via sciencedaily.com) Original source An international team of researchers lays the foundation to examine how extracellular RNA and its carrier proteins found in bodily fluids function in a healthy as well as a diseased setting, potentially providing a means to accurately implement early detection and monitor disease processes.
Published Synthetic biology meets fashion in engineered silk
(via sciencedaily.com) Original source Engineers developed a method to create synthetic spider silk at high yields while retaining strength and toughness using mussel foot proteins.
Published Reinforcement learning: From board games to protein design
(via sciencedaily.com) Original source An AI strategy proven adept at board games like Chess and Go, reinforcement learning, has now been adapted for a powerful protein design program. The results show that reinforcement learning can do more than master board games. When trained to solve long-standing puzzles in protein science, the software excelled at creating useful molecules. In one experiment, proteins made with the new approach were found to be more effective at generating useful antibodies in mice than were previous methods. If this method is applied to the right research problems, it likely could accelerate progress in a variety of scientific fields.
Published Evolution of two contagious cancers affecting Tasmanian devils underlines unpredictability of disease threat
(via sciencedaily.com) Original source Evolution of two contagious cancers affecting Tasmanian devils underlines unpredictability of disease threat. Scientists have traced the family trees of two transmissible cancers that affect Tasmanian devils and have pinpointed mutations which may drive growth of deadly diseases.
Published Fungal genetics could help develop novel biotechnologies
(via sciencedaily.com) Original source An essential pillar of Earth's ecological system, fungi have long been used to better the lives of humans. While these organisms are still vastly understudied, a new review paper suggests that their unique genomes could be used to make progress in the biotech industry.