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Categories: Biology: Cell Biology, Biology: Molecular
Published Like dad and like mum ... all in one plant
(via sciencedaily.com) Original source Scientists have established a system to generate clonal sex cells in tomato plants and used them to design the genomes of offspring. The fertilization of a clonal egg from one parent by a clonal sperm from another parent led to plants containing the complete genetic information of both parents.
Published New molecule mimics the anti-clotting action of blood-sucking organisms
(via sciencedaily.com) Original source Nature gave ticks, mosquitoes and leaches a quick-acting way to keep blood from clotting while they extract their meal from a host. Now the key to that method has been harnessed by a team of researchers as a potential anti-clotting agent that could be used as an alternative to heparin during angioplasty, dialysis care, surgeries and other procedures.
Published Research on centromere structure yields new insights into the mechanisms of chromosome segregation errors
(via sciencedaily.com) Original source Researchers have made a surprising new discovery in the structure of the centromere, a structure that is involved in ensuring that chromosomes are segregated properly when a cell divides. Mistakes in chromosome segregation can lead to cell death and cancer development. The researchers discovered that the centromere consists of two subdomains. This fundamental finding has important implications for the process of chromosome segregation and provides new mechanisms underlying erroneous divisions in cancer cells. The research was published in Cell on May 13th 2024.
Published How do genetically identical water fleas develop into male or female?
(via sciencedaily.com) Original source Researchers have used a novel combination of short-read and long-read RNA sequencing to identify the different isoforms of genes expressed in the crustacean Daphnia magna. Males and females are genetically identical, but using this technique the team revealed genes that switch the predominant isoform in a male-female-dependent manner. This study may help further advance technologies in crustacean aquaculture.
Published Nature's 3D printer: Bristle worms form bristles piece by piece
(via sciencedaily.com) Original source Molecular biologists provide exciting insights into the bristles of the marine annelid worm Platynereis dumerilii. Specialized cells, so-called chaetoblasts, control the formation of the bristles. Their mode of operation is astonishingly similar to that of a technical 3D printer.
Published Research shows that 'softer' proteins can cross into the nucleus quicker
(via sciencedaily.com) Original source Researchers have discovered that how soft or rigid proteins are in certain regions can dictate how fast or slow they enter the nucleus.
Published Cellular activity hints that recycling is in our DNA
(via sciencedaily.com) Original source Introns are perhaps one of our genome's biggest mysteries. They are DNA sequences that interrupt the sensible protein-coding information in your genes, and need to be 'spliced out.'
Published Research explores ways to mitigate the environmental toxicity of ubiquitous silver nanoparticles
(via sciencedaily.com) Original source Researchers have taken a key step toward closing the silver nanoparticles knowledge gap with a study that indicates the particles' shape and surface chemistry play key roles in how they affect aquatic ecosystems.
Published Scientists unlock key to breeding 'carbon gobbling' plants with a major appetite
(via sciencedaily.com) Original source The discovery of how a critical enzyme 'hidden in nature's blueprint' works sheds new light on how cells control key processes in carbon fixation, a process fundamental for life on Earth. The discovery could help engineer climate resilient crops capable of sucking carbon dioxide from the atmosphere more efficiently, helping to produce more food in the process.
Published New light shed on carboxysomes in key discovery that could boost photosynthesis
(via sciencedaily.com) Original source A research team has discovered how carboxysomes, carbon-fixing structures found in some bacteria and algae, work. The breakthrough could help scientists redesign and repurpose the structures to enable plants to convert sunlight into more energy, paving the way for improved photosynthesis efficiency, potentially increasing the global food supply and mitigating global warming.
Published GPS-like system shows promise as HIV vaccine strategy to elicit critical antibodies
(via sciencedaily.com) Original source A team has developed a vaccine approach that works like a GPS, guiding the immune system through the specific steps to make broadly neutralizing antibodies against HIV.
Published New Rhizobia-diatom symbiosis solves long-standing marine mystery
(via sciencedaily.com) Original source Scientists have discovered a new partnership between a marine diatom and a bacterium that can account for a large share of nitrogen fixation in vast regions of the ocean. The newly-discovered bacterial symbiont is closely related to the nitrogen-fixing Rhizobia which live in partnership with many crop plants and may open up new avenues to engineer nitrogen-fixing plants.
Published High school student helps transform 'crazy idea' into innovative research tool
(via sciencedaily.com) Original source A 'crazy idea' hatched during a walk in the woods and first tested by a high school student is now an innovative research tool used by scientists worldwide to predict neurotransmitters in fruit fly connectomes.
Published New sex-determining mechanism in African butterfly discovered
(via sciencedaily.com) Original source In a study of a species of African butterfly, researchers have discovered a previously undescribed molecular mechanism of how the sex of an embryo is initially specified.
Published Fluidic systems resembling blood vascular tissues: Artificial blood vessels and biomedicine
(via sciencedaily.com) Original source Nature has consistently inspired engineering applications. Recently, a group of researchers drew new inspirations from the vascular network and developed a new type of fluidic system named VasFluidics.
Published An epigenome editing toolkit to dissect the mechanisms of gene regulation
(via sciencedaily.com) Original source A recent study led to the development of a powerful epigenetic editing technology. The system unlocks the ability to precisely program chromatin modifications at any specific position in the genome, to understand their causal role in transcription regulation. This innovative approach will help to investigate the role of chromatin modifications in many biological processes, and to program desired gene activity responses, which may prove useful in disease settings.
Published An adjuvant made in yeast could lower vaccine cost and boost availability
(via sciencedaily.com) Original source Adjuvants make vaccines more effective, though one of the best is an expensive extract from the soap bark tree. To lower the cost and avoid the laborious extraction process from bark, synthetic biologists introduced 38 separate genes into yeast to recreate the synthesis of the active molecule, a complex chemical, QS-21, that has a terpene core and numerous sugars. This may be the longest biosynthetic pathway ever inserted into yeast.
Published Limited adaptability makes freshwater bacteria vulnerable to climate change
(via sciencedaily.com) Original source Freshwater bacteria with small genomes frequently undergo prolonged periods of adaptive stagnation. Based on genomic analyses of samples from European lakes, researchers uncovered specific evolutionary strategies that shape these bacteria's lifestyles. Understanding the evolutionary dynamics of aquatic microbial communities is key to safeguarding ecosystem services.
Published Why is breaking down plant material for biofuels so slow?
(via sciencedaily.com) Original source Tracking individual enzymes during the breakdown of cellulose for biofuel production has revealed how several roadblocks slow this process when using plant material that might otherwise go to waste. The research may lead to new ways to improve the breakdown process and make the non-edible parts of plants and other plant waste, such as forestry residue, a more competitive source of biofuels.
Published Intermittent fasting protects against liver inflammation and liver cancer
(via sciencedaily.com) Original source Fatty liver disease often leads to chronic liver inflammation and can even result in liver cancer. Scientists have now shown in mice that intermittent fasting on a 5:2 schedule can halt this development. The fasting regime reduces the development of liver cancer in mice with pre-existing liver inflammation. The researchers identified two proteins in liver cells that are jointly responsible for the protective effect of fasting. An approved drug can partially mimic this effect.