Showing 20 articles starting at article 821
< Previous 20 articles Next 20 articles >
Categories: Biology: Cell Biology, Biology: Molecular
Published Shining a new light on the tug-of-war between virus and host
(via sciencedaily.com) Original source The interplay between ribonucleic acid (RNA) and proteins is not only important for maintaining cellular homeostasis but is also at the center of the tug-of-war between virus and host. Until now, there has been no method to globally map direct interactions of individual RNA regions in an unbiased fashion without the need for genetic modification of the target RNA or cell. Researchers have now developed a breakthrough tool that overcomes this limitation.
Published Discovery of a third RNA virus linage in extreme environments Jan 17, 2024
(via sciencedaily.com) Original source A research group has discovered a novel RNA viral genome from microbes inhabiting a high-temperature acidic hot spring. Their study shows that RNA viruses can live in high-temperature environments (70-80 degrees Celsius), where no RNA viruses have been observed before. In addition to the two known RNA virus kingdoms, a third kingdom may exist.
Published Groundbreaking genome editing tools unlock new possibilities for precision medicine
(via sciencedaily.com) Original source A team of researchers has achieved a major breakthrough in genome editing technology. They've developed a cutting-edge method that combines the power of designer-recombinases with programmable DNA-binding domains to create precise and adaptable genome editing tools.
Published How seahorse-like toxins kill insects
(via sciencedaily.com) Original source Insect-killing bacteria typically release toxins to slay their hosts. The bacterium Photorhabdus luminescens, for example, pumps insect larvae full of the lethal 'Makes caterpillars floppy 1' (Mcf1) toxin, leading them to first become droopy and then dead. However, it has so far been a mystery how Mcf1 unfolds its devastating effect. Researchers successfully used cryo-electron microscopy (cryo-EM) and biochemical assays to characterize the first-ever Mcf1 structure, allowing them to propose a molecular mechanism of the toxin's action. Understanding how bacterial toxins perform their deadly task in such detail is very useful for engineering novel biopesticides, thereby reducing the use of barely specific chemical agents with harmful side effects for the ecosystem.
Published Engineering viruses to kill deadly pathogens
(via sciencedaily.com) Original source Antimicrobial resistance is an urgent and growing global crisis. Researchers are exploring phages, viruses that infect bacteria, as a possible solution. In the new study, researchers successfully modified DNA from four types of phages to kill a deadly pathogen. The process can also be used to produce more phage variants for further exploration.
Published When and how immune cells decide to form pathogen memories
(via sciencedaily.com) Original source During infection, reversible switch permits flexible formation of memory T cells, long-lived blood cells that can remember pathogen encounters and respond upon reinfection.
Published Using computers to design proteins allows researchers to make tunable hydrogels that can form both inside and outside of cells
(via sciencedaily.com) Original source New research demonstrates a new class of hydrogels that can form not just outside cells, but also inside of them. These hydrogels exhibited similar mechanical properties both inside and outside of cells, providing researchers with a new tool to group proteins together inside of cells.
Published A green alternative for treating Streptococcus iniae bacteria in hybrid striped bass
(via sciencedaily.com) Original source Scientists have developed a green antibiotic alternative to treat the deadly pathogen Streptococcus iniae in hybrid striped bass, the fourth most farmed finfish in the United States, according to a recent study.
Published DNA particles that mimic viruses hold promise as vaccines
(via sciencedaily.com) Original source Using a DNA-based delivery particle, researchers created a vaccine that can induce a strong antibody response against SARS-CoV-2.
Published Asparagus and orchids are more similar than you think
(via sciencedaily.com) Original source How is a beech leaf constructed? What determines the appearance of an asparagus? A new 'encyclopaedia' helps us learn more about the building blocks of plants. The encyclopaedia, probably the largest of its kind, could be used to improve targeted plant breeding efforts, to make them both more climate-resilient and more easily digestible.
Published Using CRISPR technology, researchers succeed in growing tomatoes that consume less water without compromising yield
(via sciencedaily.com) Original source Scientists have succeeded in cultivating and characterizing tomato varieties with higher water use efficiency without compromising yield. The researchers, employing CRISPR genetic editing technology, were able to grow tomatoes that consume less water while preserving yield, quality, and taste.
Published Resin destroys coronavirus from plastic surfaces
(via sciencedaily.com) Original source Researchers are currently developing anti-viral surfaces to decrease the spread of infectious diseases. A recent study found that a resin ingredient is effective against coronaviruses and strongly decreases their infectivity on plastic surfaces.
Published Poultry scientists develop 3D anatomy technique to learn more about chicken vision
(via sciencedaily.com) Original source Poultry scientists are unraveling the complexities of bird brains and finding less expensive ways to do it. The scientists mapped the intricate neurological pathways that control vision in chickens with detailed 3D models of the connections between the eyes and four regions of the brain.
Published Tomato juice's antimicrobial properties can kill salmonella
(via sciencedaily.com) Original source New research shows that tomato juice can kill Salmonella Typhi and other bacteria that can harm people's digestive and urinary tract health.
Published 'Genomic time machine' reveals secrets of our DNA
(via sciencedaily.com) Original source Researchers reveal a novel method to uncover bits of our genetic blueprint that come from ancient genetic parasites, offering fresh insights into human evolution and health.
Published A non-allergenic wheat protein for growing better cultivated meat
(via sciencedaily.com) Original source As the world's population increases, cultivated or lab-grown meat -- animal muscle and fat cells grown in laboratory conditions -- has emerged as a potential way to satisfy future protein needs. And edible, inexpensive plant proteins could be used to grow these cell cultures. Now, researchers report that the non-allergenic wheat protein glutenin successfully grew striated muscle layers and flat fat layers, which could be combined to produce meat-like textures.
Published Probiotics promote weight loss in obese dogs
(via sciencedaily.com) Original source New research demonstrates how probiotics can reshape the gut microbiome and energy metabolism in dogs.
Published Cosmic building blocks of life discovered through the electron microscope
(via sciencedaily.com) Original source Meteorites are fragments of asteroids which find their way to Earth as shooting stars and provide information on the origins of our solar system. A team of researchers has examined the so-called Winchcombe meteorite and demonstrated the existence in it of nitrogen compounds such as amino acids and heterocyclic hydrocarbons -- without applying any chemical treatment and by using a new type of detector design.
Published How obesity dismantles our mitochondria
(via sciencedaily.com) Original source Researchers found that when mice were fed a high-fat diet, mitochondria within their fat cells broke apart and were less able to burn fat, leading to weight gain. They also found they could reverse the effect by targeting a single gene, suggesting a new treatment strategy for obesity.
Published Researchers map genome for cats, dolphins, birds, and dozens of other animals
(via sciencedaily.com) Original source Researchers mapped genetic blueprints for 51 species including cats, dolphins, kangaroos, penguins, sharks, and turtles, a discovery that deepens our understanding of evolution and the links between humans and animals. The researchers developed novel algorithms and computer software that cut the sequencing time from months -- or decades in the case of the human genome -- to a matter of days.